Research works
The research papers we track — the newest first. Works with a plain-language summary link to it.
128635 work(s)
- Society & EconomicsOpen access
The 1994 Rwandan genocide remains one of the clearest examples of the international community’s failure to prevent mass atrocities despite credible warnings of impending violence. This paper examines the roles of Belgium, the United Nations Secretariat, the United States, and Fra...
- AI & ComputingOpen access
Andrew's order (Base 44 console): [SELF-BUILD from enhancement #492] Add German term cluster 189 to E8 multilingual root vector dictionary. Map its 22 compressed geometric discoveries using 0.649 compression index. Update cross-lingual pattern retrieval module and eToro demo exec...
- Biology
Immune evasion by cancer cells remains a major barrier to the success of immune checkpoint blockade (ICB). In recent years, Protein tyrosine phosphatase non-receptor type 2 (PTPN2) has emerged as a promising and druggable target for cancer immunotherapy. Small-molecule agents cur...
- Health & Medicine
Rondaptivon pegol (BT200) is a PEGylated RNA aptamer that prolongs von Willebrand factor (VWF) and factor VIII half-lives in patients with hemophilia A and von Willebrand disease (VWD) type 2B. Embryo–fetal safety is particularly relevant given the disproportionate disease burden...
- Society & Economics
Purpose This research aims to analyze how mandatory ESG reporting legislation affects executive opportunism through the quality of financial reporting. The study also examines audit efficacy and media attention as mechanisms and explains the moderating effect of ESG-linked pay on...
- Climate & Environment
Numerical-Based Feasibility Study of Road Culvert Deicing Using Geothermal Energy in Montana
Abstract This study presents a numerical evaluation of a geothermal culvert deicing system to mitigate ice buildup and thermal degradation of frost-susceptible soils in cold regions such as Montana. A three-dimensional numerical model was developed in COMSOL Multiphysics (version...
- Health & Medicine
Polyunsaturated fatty acids (PUFAs) play a crucial role in tumor development by influencing not only tumor cells but also immune cells within the tumor microenvironment. Here, we explored the mechanisms by which PUFAs are transported and function within immune cells to regulate t...
- BiologyOpen access
Potatoes are one of the major crops eaten in developing countries; however, their production is falling due to various diseases. Early identification and detection of potato leaf diseases play a vital role in improving potato quality and quantity. Existing methods are either comp...
- Society & Economics
Scholarship surrounding the Kraepelinian dichotomy of dementia praecox and manic-depressive insanity has overwhelmingly approached Kraepelin's nosology as the product of Kraepelin's clinical method, use of diagnostic cards, and pre-existing disease concepts, rather than his work...
- BiologyOpen access
To characterize the transcriptomic dynamics underlying shell hardening in Macadamia integrifolia, RNA sequencing was performed on pericarp and shell tissues collected at three key developmental stages. A total of 18 libraries were generated, yielding 125.19 Gb of clean data. Gene...
- Society & EconomicsOpen access
The October Revolution: perceptions by contemporaries versus generational memory
Abstract This article examines the problem of constructing a Soviet myth of the October Revolution supplemented by consistent exclusion of alternative contemporaneous interpretations. Building on theories of cultural and communicative memory (Halbwachs; Assmann), the analysis inv...
- Health & MedicineOpen access
Abstract Background Maintenance hemodialysis patients exhibit low physical activity, which is associated with sarcopenia, increased risk of cardiovascular events, and elevated all-cause mortality. Social support is an important resource for promoting healthy behaviors. But the me...
- Health & MedicineOpen access
Contingency Management for Smoking Cessation Among Adults Experiencing Homelessness
Importance: More than 70% of people experiencing homelessness report current smoking. Contingency management (CM) interventions that provide financial incentives for smoking cessation have shown short-term promise, but extended CM interventions have not been well studied in this...
- Society & EconomicsOpen access
ABSTRACT Objective The role of the therapeutic alliance (TA) in treatment outcomes of anorexia nervosa (AN) appears to be less substantial than in other disorders. However, the therapeutic process is a complex trajectory with many variables influencing each other. Hence, investig...
- Climate & Environment
A new framework for non-stationary spatio-temporal data fusion of multi-fidelity models
We propose a new scalable framework for spatio-temporal data fusion with multi-fidelity Gaussian processes (MFGPs) that enables fully likelihood-based inference for both stationary and non-stationary fidelity integration. The framework is designed for environmental applications,...
- Health & Medicine
Service evaluation project: a journey through dementia distress management
Purpose Care home (CH) residents with dementia may exhibit distressed behaviours due to unmet needs, with non-pharmacological interventions being the first line intervention. This study aims to evaluate the efficiency of the Distressed Behaviour Pathway (DBP), delivered to care h...
- Health & MedicineOpen access
The Untested Organisation: A Case for Examining Organisational Capability Before Failure
Modern organisations test the products, systems, controls and people they depend on before relying on them. Failure, when it occurs, is investigated afterwards: inquiries and reviews reconstruct the governance, incentives, culture and decision-making that made it possible, and co...
- Health & MedicineOpen access
Hepatocyte OTUD1 promotes hepatic stellate cell activation and liver fibrosis by stabilizing HSP90β
Crosstalk between parenchymal and nonparenchymal cells of the liver mediates the activation of hepatic stellate cells (HSCs). Activated HSCs transform into myofibroblasts and produce the extracellular matrix (ECM), and massive ECM accumulation can affect liver function and eventu...
- Engineering & TechnologyOpen access
End milling is widely used to manufacture ribs, pockets, frames, and other structural features in mechanical and aerospace components. The resulting sidewall topography can affect dimensional accuracy, functional performance, and fatigue behaviour, so its prediction is relevant d...
- Health & Medicine
INTRODUCTION: Preoperative neutrophil-lymphocyte ratio (NLR) has been found in various fields to be a predictor of post-operative pain and functional outcomes. To date no studies have looked at NLR in relation to patient outcomes after anterior cervical discectomy and fusion (ACD...