Research works

Time-Varying Effects of Valacyclovir Prophylaxis in the Zoster Eye Disease Study

Importance The Zoster Eye Disease Study (ZEDS) supports consideration of suppressive valacyclovir for 1 year to reduce risk of recurrent keratitis or iritis in patients with herpes zoster ophthalmicus (HZO). Although the primary outcome did not show benefit of suppressive valacyc...

The Decentralized Fraud Matrix (DFM)

Through this independent concept, the study introduces a fresh new perspective to the world of modern forensic accounting via a theory called “The Decentralized Fraud Matrix” (DFM). This conceptual research was developed specifically as an analytical tool to dissect the modus ope...

Designing and evaluating a neuroanatomy learning experience using multiple external representations

Abstract Neuroanatomy is challenging, requiring multiple external representations (MER) for comprehension. While studies have examined individual representations of neuroanatomy, a gap remains in understanding how students link across MER, especially between technology‐generated...

En Bloc Resection of Inferior Vena Cava Leiomyosarcoma with Prosthetic Caval Reconstruction and Renal Autotransplantation: A Case Report

Background: Inferior vena cava (IVC) leiomyosarcoma is a rare vascular malignancy for which complete surgical resection remains the only potentially curative treatment. Surgical management is technically demanding, particularly when the tumor involves the renal veins and retrohep...

On the Convergence of JPEG Multiple Compression for Digital Forensics

Convergence means that the limit of the sequence will tend to a certain value. In some forensic scenarios, if the same manipulation is repeatedly performed on an image, the resulting image sequence tends to converge. Credible forensics can be achieved by utilizing this convergenc...

Experimental investigation and optimization of 3D-printed circumferentially corrugated multi-cell polygonal structures

Purpose This study aims to investigate the crashworthiness of 3D-printed multi-cell thin-walled polylactic acid plus (PLA+) tubes under quasi-static axial compression. The objective is to explore the influence of inner geometry, radius application and diameter variations on crash...

Hesperetin-Loaded PLGA Nanoparticles Ameliorate Cisplatin-Induced Oxidative Stress and Testicular Dysfunction in Rats: Association with NRF2/HO-1, NF-κB, and ACSL4/GPX4/SLC7A11 Signaling Modulation

Background: Cisplatin is a widely used chemotherapeutic agent whose gonadotoxic effects, largely driven by oxidative stress and inflammation, pose a major threat to male reproductive health. This study evaluated whether hesperetin (HES) and hesperetin-loaded poly (lactic-co-glyco...

آدم والإنسان المسؤول | Adam and the Answerable Being — Islam, Evolution, and the Constitution of Moral Humanity

Adam and the Answerable Being | آدم والإنسان المسؤول is a standalone scholarly work examining Adam, Islam and evolution, human origins, Qur'anic anthropology, and the constitution of moral responsibility. It asks a question deeper than the biological history of Homo sapiens: what...

Mechanochemically Prepared Supported Ionic Liquids for Efficient Glycerol Valorization to Glycerol Carbonate

Abstract The valorization of glycerol, a major byproduct of the biodiesel industry, into high value chemicals offers a sustainable pathway to support circular economy objectives within biorefineries. Among various transformation routes, the transesterification of glycerol with di...

Sustainable Leadership, Workplace Integration, and Resilience Among Staff Nurses: A Cross-Sectional Correlational Study

Background: Sustainable leadership has emerged as a critical approach for promoting long-term organizational effectiveness and workforce well-being in healthcare settings. However, empirical evidence linking sustainable leadership to workplace integration and resilience among nur...

ODARRL: Obstacle- and Disturbance-Aware End-to-End Residual Reinforcement Learning for Underwater Robot Trajectory Tracking with Obstacle Avoidance

ROVs are essential for marine exploration and underwater operations, yet conventional teleoperation relies heavily on skilled human operators, and many autonomous methods stop at high-level planning rather than low-level actuation, limiting robustness in disturbed and cluttered e...

Photoinduced Atom Transfer Radical Addition for the Functionalization of Carbon–Carbon Multiple Bonds

Photoinduced atom transfer radical addition (ATRA) has become a powerful strategy for the vicinal functionalization of carbon–carbon multiple bonds in alkenes and alkynes, garnering significant attention due to its high efficiency, mild conditions, operational simplicity, and exc...

Deep Learning‐Based Enhancement of Already Diagnostic‐Quality MRI for Alzheimer's Disease Classification: Effects on Model Performance and Training Data Requirements

ABSTRACT Background Deep learning (DL)‐based image enhancement is widely used to improve suboptimal medical imaging. Whether it also benefits diagnostic‐quality MRI in downstream task performance and data‐efficiency remains unclear. Purpose To investigate the impact of DL‐based e...

Explicit and refined QUBO modeling of anomalously reflective metasurfaces for annealing-assisted design optimization

This paper presents an annealing-assisted optimization framework for anomalously reflective metasurface design based on quadratic unconstrained binary optimization (QUBO) modeling. First, an explicit QUBO formulation is derived under the physical optics (PO) approximation, enabli...

Unraveling the molecular Nexus of Alzheimer’s Disease and HIV encephalitis: The role of cellular senescence and transcriptional regulation

Alzheimer’s disease (AD) and HIV-associated neurocognitive disorder (HAND) share progressive cognitive decline. Their common molecular mechanisms remain poorly understood. Current therapeutic approaches lack effective biomarkers for early diagnosis and intervention. We integrated...

Single-cell profiling of peripheral blood mononuclear cells in diverse men with prostate cancer reveals a fatal disease-associated immune signature

Abstract Alterations in peripheral immunity may contribute to fatal prostate cancer and the excessive disease burden among African American (AA) men. Thus, we investigated peripheral immunity in prostate cancer patients in association with disease outcome and AA descent. We perfo...

LAB #986 PROMISING: LEDGER BENCH: Apply filter: XAUUSD LONG @ ASIAN with 5 conf — improves win rate from 31.6% to 66.7% — E8 Intelligence Research

IDEA: Adjustment made to the live model — verify against the backtests: Apply filter: XAUUSD LONG @ ASIAN with 5 conf — improves win rate from 31.6% to 66.7% (+35.0pp, n=21) SAME-WINDOW EFFECT: Over the current trade window, applying the XAUUSD LONG @ ASIAN with 5 conf filter wou...

Joint high level of low-density lipoprotein and high-sensitivity C-reactive protein are associated with early neurological deterioration after thrombolysis in patients with mild stroke

Low-density lipoprotein (LDL) and high-sensitivity C-reactive protein (hs-CRP) play important roles in cardiovascular and cerebrovascular diseases through pathways such as inflammation and oxidative stress. We aimed to explore whether LDL and hs-CRP were associated with early neu...

Failure Modes of Total Wrist Arthroplasty: Cross-Sectional Analysis of FDA MAUDE Adverse Event Reports (2015-2025)

Background: Total wrist arthroplasty (TWA) is a motion-preserving alternative to wrist fusion for end-stage wrist arthritis, but concerns regarding long-term durability continue to limit broader use. Reported 10-year survivorship ranges from 70% to 80%, although real-world failur...

Prevalence and Antimicrobial Resistance of Pseudomonas aeruginosa Recovered from Respiratory and Urinary Specimens in a Lebanese Hospital (2020–2025)

Background: Respiratory tract infections (RTIs) and urinary tract infections (UTIs) are among the most common infections in humans. It is estimated that millions of deaths occur each year worldwide due to these infections. Pseudomonas aeruginosa (P. aeruginosa), in particular, re...