Research works
The research papers we track — the newest first. Works with a plain-language summary link to it.
128635 work(s)
- Health & Medicine
Background: Rheumatoid arthritis (RA) is a chronic autoimmune inflammatory disorder characterised by persistent synovitis, progressive cartilage and subchondral bone destruction, functional disability and systemic complications. Current disease-modifying therapy has substantially...
- Biology
TPS10 contributes to linalool emission in rice in response to brown planthopper infestation
Abstract BACKGROUND Terpenoids, a prominent class of herbivore‐induced plant volatiles, play a crucial role in plant responses to insect attacks. However, the precise ecological functions of individual terpene synthases in rice defense mechanisms remain unclear. RESULTS The level...
- BiologyOpen access
Aligning protein-generative models to experimental fitness with ProteinDPO
Abstract Biological generative models can predict biological functions without task-specific training data but often under-perform specialized models. This is due to a fundamental ‘alignment gap’, where the rules learned during unsupervised training are not related to the functio...
- BiologyOpen access
Aspergillus flavus, a ubiquitous phytopathogen, produces mycotoxins, especially aflatoxin B1 (AFB1), and infects crops worldwide. Glycerol-3-phosphate dehydrogenase (G3PDH) is a key enzyme in the glycerol synthesis and metabolic pathway catalyzing the reversible conversion reacti...
- Health & MedicineOpen access
Abstract Background SARS-CoV-2 remains a global health threat because ongoing viral evolution and immune evasion reduce the effectiveness of existing therapies. SNS812 is an inhaled small interfering RNA targeting a highly conserved region of the viral RNA-dependent RNA polymeras...
- Engineering & TechnologyOpen access
Hemodynamic integration in extracorporeal membrane oxygenation anticoagulation
Despite progressive advances in circuit design, material biocompatibility, and anticoagulation monitoring, bleeding and thrombosis remain common during extracorporeal membrane oxygenation and are closely associated with adverse outcomes. Current practice still relies mainly on he...
- Materials & Energy
지구온난화로 인해 이상기후 현상이 심화되면서 화석연료를 대체할 에너지원으로 수소에너지가 주목받고 있다. 하지만, 기체수소는 높은 위험성으로 인해 배터리에 비해 대중화가 더딘 실정이다. 본 연구에서는 기체수소의 고압 위험성을 개선한 액체수소 저장시스템에 적용되는 압력해소밸브에 대하여...
- Health & MedicineOpen access
To develop and validate machine learning models for predicting match outcomes in elite kickboxing based on technical-tactical performance indicators and to identify the key variables distinguishing winners from defeated athletes. Video analysis was conducted on 142 elite kickboxi...
- Engineering & TechnologyOpen access
To investigate the mechanical response of anchorage bearing structures in deep roadways under dynamic loading, a physical simulation test was conducted to analyze the evolution of the strain field under combined static and dynamic loads. A mechanical load-transfer model of the an...
- Health & MedicineOpen access
This randomized controlled trial evaluated the efficacy of home-based treatment programs for chronic radiation associated dysphagia (CRAD) in head and neck cancer (HNC) patients, comparing high-volume strength training to combined strength-skill training with either real or sham...
- Materials & EnergyOpen access
Hybridizing MXenes with MOFs: a pathway to smart sensing platforms and efficient water remediation
The need for the efficient platforms creating innovative applications in the field of sensing, wastewater treatment, and industrial safety has resulted in the development of novel and advanced hybrid materials with unique morphological structures and superior performance. Hybrid...
- Health & MedicineOpen access
Objectives: This study assessed the economic value of 2 major initiatives within the national infectious disease response system of the Korea Disease Control and Prevention Agency (KDCA): the Training Programs for Public Health Workforce (TPPHW) and the Infectious Disease Informa...
- AI & Computing
화성은 태양계 행성 중 높은 생명체 존재 가능성을 가지고 있다. 또한, 지구 외 새로운 거주지로서 화성 탐사에 대한 시도가 지속되고 있다. 최근에는 화성 탐사를 위한 로버뿐 아니라 유인 탐사선을 보내기 위해 탐사선 크기는 커지고 있다. 이에 따라 탐사선의 성공적인 착륙을 위한 감속 시스템이...
- Health & MedicineOpen access
Needle-free jet injectors are a promising alternative to conventional dental needles, particularly for patients with injection-related fear. However, the actuation mechanism can substantially affect jet formation, delivery consistency, and tissue penetration. This study compared...
- Health & MedicineOpen access
Patients undergoing laparoscopic cholecystectomy (LC) may experience severe postoperative pain. Peripheral nerve blocks, as a component of multimodal analgesia, are now widely employed in postoperative pain management. This study investigated the effects of modified thoracoabdomi...
- Climate & EnvironmentOpen access
The use of climate reference regions is a common practice in climate change research and impact assessment studies 1 , 2 , 3 , 4 , having been utilized especially within the context of the Intergovernmental Panel on Climate Change (IPCC)’s Assessment Reports (ARs) over the past 2...
- Engineering & TechnologyOpen access
Nonflammable electrolytes are pivotal for improving the safety of potassium-ion batteries. However, their broad adoption has been hindered by the inadequate electrode compatibility of conventional nonflammable electrolytes, which typically result from strong solvation and excessi...
- Health & MedicineOpen access
Perforated acute appendicitis on computed tomography revealing underlying tuberculosis
Tuberculous appendicitis is an extremely rare manifestation of gastrointestinal tuberculosis and is often clinically and radiologically indistinguishable from conventional acute appendicitis. We report the case of a 27-year-old man who presented with fever and pain in the right l...
- Health & MedicineOpen access
Interdisciplinary team-based rheumatology care models are a promising solution for improving access to high quality, equitable care for people with rheumatic and musculoskeletal disorders. There is limited understanding on health professionals’ perspectives on their needs to deli...
- Health & MedicineOpen access
Endometrial polyps (EP) are common, and hysteroscopic polypectomy is the reference treatment, but recurrence is frequent. This study aimed to identify risk factors for recurrence and to develop and internally validate a nomogram for individual postoperative risk stratification. I...