Research works

The Impact of Adverse Childhood Experiences on Youth’s Mental Health: What is the Role of Family Resilience?

Abstract Given that many adverse childhood experiences (ACEs) are family-contextual and that family processes shape youth mental health, the current study examined the role of family resilience in the relationship between ACEs and major mental health outcomes among youth aged 6–1...

Preliminary Clinical Outcomes of an Alternating-Current-Assisted Implant Surface Decontamination Protocol: A Prospective Case Series with 12-Month Follow-Up

Background: Treatment of peri-implantitis remains challenging because biofilm removal from microstructured implant surfaces is often incomplete. The present study is an uncontrolled, prospective feasibility case series involving six patients (six implants), not a controlled clini...

Prediction of coagulation factor inhibitor levels using Random Forest model based on the activated partial thromboplastin time (aPTT) mixing study: model development and prototype application

Abstract Objectives This study aimed to develop a machine learning approach to predict factor VIII inhibitor titers from activated partial thromboplastin time (aPTT) mixing study data. Methods Records of 173 patients who underwent factor VIII inhibitor testing at Songklanagarind...

The Architecture of Equilibrium

│ Current autonomous agent architectures suffer from perpetual agitation: unconstrained context growth, non-deterministic heap allocations, and runaway inference costs. Without a native ground state, long-horizon agents accumulate entropy, hallucinate, and drift. │ │ The Architec...

Ultralow‐Dose Direct Photopatterning of Metal–Organic Frameworks for Scalable Device Integration

ABSTRACT The integration of metal–organic frameworks (MOFs) into microelectronic and optoelectronic devices requires patterning strategies that combine high sensitivity, structural preservation, and compatibility with scalable fabrication. Direct optical patterning offers a photo...

Formulation Strategies for Next-Generation Bispecific Antibodies: Design Considerations and Stability Implications

Bispecific antibodies (BsAbs) represent a transformative class of next-generation biologics, enabling simultaneous binding to two targets and offering mechanisms of action beyond conventional monoclonal antibodies. Their growing clinical success, particularly in T-cell–redirectin...

Multispecies Mesocosms Evaluating Ongoing PCB Recontamination of Novel In Situ Sediment Remedies

Novel thin-layer sand coverings for in situ sediment remediation may be vulnerable to recontamination, elevating bioavailable polychlorinated biphenyls (PCBs) within and just above the thin layer. A series of 3-month marine mesoscale experiments containing sheepshead minnows (Cyp...

Application of extracellular polymeric substances recovered from aerobic granular sludge as bio-based hydrogels for plant cultivation systems

Wastewater treatment plants generate large amounts of excess sludge, whose management represents an environmental and economic challenge, motivating resource recovery strategies in line with European Union Directive 2024/3019. Among these, the extraction of extracellular polymeri...

Spatial Variations in the Socio-economic Status of Female Street Vendors: Insights from Varanasi City

Abstract The present study examines the socio-economic status of female street vendors in Varanasi, India, with particular emphasis on inter-area variations in livelihood conditions. The study is based on primary data collected from 300 female street vendors selected from three c...

Dynamic User Equilibrium for Electric Vehicle Departure Time and Path–Charging Choices with Wireless and Fast Charging Services

This study investigates how coordinated wireless and fast charging services reshape electric vehicle departure time and path–charging choices when a trip-level charging requirement must be completed before arrival. A multi-class dynamic user equilibrium model is formulated for ro...

From Waste to Wealth: Boosting Productivity in Kenyan Smallholder Farmer Fields with Fluopyram-Treated Banana Fibre

Potato (Solanum tuberosum) is a key staple crop in Kenya, where plant-parasitic nematodes are among the most damaging yield constraints for smallholder farmers. This study evaluated fluopyram-treated banana fibre paper, a biodegradable carrier for targeted delivery of ultra-low n...

Quantification of Phosphorylated Tau Protein in Alzheimer's Disease Patients’ Fluids With Electrolyte‐Gated Organic Transistor Biosensors

ABSTRACT Dementia is a syndrome that affects millions of people in the world, and Alzheimer's disease (AD) is the most common cause. The diagnosis of AD begins with cognitive symptoms such as mild cognitive impairment (MCI) but requires the demonstration and quantification of the...

Short-chain fatty acids as key mediators of the microbiota–gut–brain axis in chronic cerebral hypoperfusion: mechanisms and therapeutic

Abstract Chronic cerebral hypoperfusion (CCH) is an important contributor to vascular cognitive impairment and neurodegenerative disorders, characterized by neuronal injury, blood–brain barrier (BBB) disruption, neuroinflammation, mitochondrial dysfunction, and synaptic impairmen...

Bifurcations of Two Symmetric Classes of Central Configurations

Abstract We consider the bifurcations of symmetric classes of central configurations formed by four and five bodies, namely the centered equilateral triangle and the centered regular tetrahedron. Results in the current literature have been obtained for a varying central mass and...

Topological Compressibility of the Yang-Mills Vacuum: A Semiclassical Prediction for Lattice QCD

We treat the areal density of centre vortices as the order parameter of a homogeneous Ginzburg-Landau functional for the SU(3) vacuum. The quadratic coefficient is fixed, with no free parameters, by the one-loop thick-vortex effective action of Diakonov and Maul, which is negativ...

From soil disruption to biodegradation: A comprehensive review of microplastic effects and microbial breakdown mechanisms in terrestrial ecosystems

Abstract Microplastics (MPs) are pervasive in the environment, posing a significant global environmental challenge. Agricultural ecosystems are particularly vulnerable to MP contamination due to the extensive use of plastics in farming practices. This issue is further aggravated...

( S )‐Pyrrolo[1,2‐ a ]pyrazine‐3‐carboxamide Analogs as Dual Akt/JNK Modulators With Antiproliferative Effects in MDA‐MB‐468 Cells

Triple‐negative breast cancer (TNBC) remains a major clinical challenge due to the absence of effective targeted therapies. In this study, thirty analogs of ( S )‐1‐oxo‐1,2,3,4‐tetrahydropyrrolo[1,2‐ a ]pyrazine‐3‐carboxamide ( A1 – F5 ) were designed, synthesized, and evaluated...

Navigating Sexualization by Clients: Critical and Clinical Perspectives

A challenging aspect of practice for social work students is the client's expression of sexual feelings for them. From a feminist perspective, sexualization by clients may be seen as an expression of gendered power dynamics. Historically, the emergence of sexual feelings on the p...

EuroMillions Breakthrough Mining — 2957 Sources, 25144 Leads Extracted — E8 Intelligence Research

Mined 2957 lottery+quantum breakthroughs. Extracted 25144 leads across 13 categories. 22847 high-value leads found. Categories: {"CORRIDOR": 2133, "FORMULA": 1967, "GEOMETRIC": 885, "FORWARD_ATTEMPT": 2264, "QUANTUM": 2477, "TIMING": 269, "CELESTIAL": 2054, "GEMATRIA": 2162, "CON...

UK–Africa Leadership Fellowship for Antimicrobial Stewardship (UK-ALF-A): A Bilateral Learning Approach to Advancing AMS Expertise Among Pharmacists

Background: Antimicrobial resistance is a growing global health challenge, particularly in low- and middle-income countries where antimicrobial stewardship (AMS) implementation and leadership capacity remain limited. Pharmacists play a central role in AMS but often lack access to...