Research works

FORMULATION AND CHARACTERIZATION OF CONTROLLED SELF PORE FORMING TABLET OF ROSIGLITAZONE

Controlled self-pore forming osmotic tablet systems are advanced oral drug delivery systems designed to provide predictable and sustained drug release, independent of gastrointestinal pH and motility. The present study aimed to formulate and characterize a controlled self-pore fo...

PHYSICOCHEMICAL ANALYSIS OF SHANKHDRAV RASA AND ITS IN-VITRO CYTOTOXIC ACTIVITY ON HT – 29 HUMAN COLORECTAL ADENOCARCINOMA CELL LINE

Ayurveda emphasizes the maintenance of health through the balance of Dosha, Agni, and Dhatu, while Rasa Shastra and Bhaishajya Kalpana describe pharmaceutical techniques for preparing safe and effective medicines. Shankhadrav Rasa is a classical distillation-based formulation pos...

DESIGN SYNTHESIS AND EVALUATION OF IMIDAZOLE [4,5 -B] PYRIDINE BENZO-HYDRAZONE

“The present research focuses on the design, synthesis, and biological evaluation of novel hybrid molecules comprising imidazo[4,5-b] pyridine and benzo-hydrazone scaffolds, aiming to explore their therapeutic potential as antimicrobial, antioxidant, and anticancer agents. A seri...

DEVELOPMENT AND VALIDATION OF UV SPECTROPHOTOMETRIC METHODS FOR SIMULTANEOUS ESTIMATION OF DEXLANSOPRAZOLE AND DOMPERIDONE IN PHARMACEUTICAL DOSAGE FORM

A simple and precise UV spectroscopic method was developed for simultaneous estimation of Dexlansoprazole (DXL) and Domperidone (DOM) using methanol as a solvent. The simultaneous estimation was carried out by developing an Absorbance Correction Method wherein at 283 nm, both the...

A REVIEW ON GREEN HPLC METHOD DEVELOPMENT FOR DISSOLUTION PROFILING OF PHARMACEUTICAL DRUGS

The development of Green High-Performance Liquid Chromatography (Green HPLC) offers the prospect of an environmentally sustainable method of pharmaceutical analysis. Traditional HPLC techniques have been associated with the use of harmful organic solvents and production of large...

THE ANALYTICAL METHOD DEVELOPMENT AND VALIDATION FOR SIMULTANEOUS ESTIMATION OF FEXOFENADINE HYDROCHLORIDE COMBINATION WITH PHENYLEPHRINE HYDROCHLORIDE (API) AND LIQUID DOSAGE FORM BY RP-HPLC

The present study focuses on the development and validation of a simple, precise, and reliable analytical method for the estimation of fexofenadine hydrochloride combination with phenylephrine hydrochloride (API) and liquid dosage form using reverse phase high-performance liquid...

DEVELOPMENT AND VALIDATION OF RP-HPLC METHOD FOR ATOMOXETINE HYDROCHLORIDE AND SODIUM BENZOATE IN PHARMACEUTICAL DOSAGE FORM

A simple, precise, and stability-indicating reversed-phase high-performance liquid chromatographic (RP-HPLC) method was developed and validated for the simultaneous estimation of Atomoxetine Hydrochloride and Sodium Benzoate in pharmaceutical oral liquid dosage form. Chromatograp...

ARTIFICIAL INTELLIGENCE IN DRUG RESPONSE PREDICTION AND PHARMACOLOGICAL THERAPY OPTIMIZATION: ADVANCES, CHALLENGES, AND FUTURE PERSPECTIVES

Driven by artificial intelligence, or AI, today's medicinal science has the potential of rapidly transforming a doctor's knowledge of patient reactions to a variety of medications. In clinical practice, one has seen that sometimes a given medication is effective and sometimes ine...

HYDROCOLLOIDS AND EMULSIFIERS IN FOOD AND ITS SYNERGISTIC EFFECTS

Hydro collides and emulsifiers are the major multipurpose food ingredient, often used in the food system for its improvement, foods when subjected to major processing technologies which require the heat, light, and energy, to function. However, the use of these processing technol...

LITERARY REVIEW ON RAKTAPRADAR

Raktapradar is a common gynecological disorder described in Ayurveda, characterized by excessive or prolonged menstrual bleeding, with or without bleeding between menstrual cycles. It is referred to as Asrigdara or Raktapradar, where abnormal uterine bleeding occurs either during...

A REVIEW ON GREEN HPLC METHOD DEVELOPMENT FOR DISSOLUTION PROFILING OF PHARMACEUTICAL DRUGS

The development of Green High-Performance Liquid Chromatography (Green HPLC) offers the prospect of an environmentally sustainable method of pharmaceutical analysis. Traditional HPLC techniques have been associated with the use of harmful organic solvents and production of large...

CLINICAL EVALUATION OF TOPICAL ASHWATHA (FICUS RELIGIOSA LINN.) OINTMENT IN THE MANAGEMENT OF PARIKARTIKA (ACUTE FISSURE-IN-ANO): A SINGLE CLINICAL CASE REPORT

Background: Parikartika (Acute Fissure-in-Ano) is a distressing anorectal disorder characterized by severe cutting pain (Parikartanavat Vedana), intense burning sensation (Daha), fresh rectal bleeding (Rakta Srava), and persistent internal anal sphincter spasm. Modern conservativ...

AVABAHUKA (FROZEN SHOULDER) IN AYURVEDA: A CRITICAL REVIEW WITH SPECIAL REFERENCE TO MARMA CHIKITSA AND CLINICAL OUTCOMES

Avabahuka is a Vata Vyadhi characterised by pain, stiffness, and restricted movements of the shoulder joint. Classical Ayurvedic texts describe the condition as resulting from aggravated Vata localised in the Amsa Pradesh, causing shoshana of Amsa Bandhana and akunchana of sira,...

VERNAKALANT HYDROCHLORIDE FOR THE RAPID CONVERSION OF RECENT-ONSET ATRIAL FIBRILLANTION: PHARMACOLOGY, CLINICAL EFFICACY, AND SAFETY

Background: Atrial fibrillation is a common arrhythmia associated with stroke risk. Vernakalant hydrochloride is an intravenous, atrial-selective antiarrhythmic developed for the rapid conversion of recent-onset AF, offering an alternative to amiodarone, which may cause systemic...

AGNI DUSHTI AND ITS ROLE IN THE ETIOPATHOGENESIS OF PSORIASIS: AN INTEGRATIVE REVIEW OF AYURVEDIC AND MODERN PERSPECTIVES

Background: Psoriasis is a chronic, immune-mediated inflammatory dermatosis with complex etiopathogenesis. Ayurveda classifies it under Kushtha (predominantly Kitibha and Ekakushtha), where Agni Dushti — impairment of digestive and metabolic fire — is identified as a central upst...

SATTVA SARATA IN TODAY'S YOUTH: A REVIEW OF THE CLASSICAL AYURVEDIC CONCEPT AND ITS RELEVANCE TO MODERN BEHAVIOURAL PROBLEMS

Young people today are often called restless, easily distracted, and quick to feel confused. Along with this, daily routines have become irregular, home-cooked food has reduced, and time spent on screens has gone up a great deal. This paper looks at these problems through an old...

LIFESTYLE MODIFICATION, SLEEP HYGIENE AND PHARMACOTHERAPY OF CHRONIC INSOMNIA

Chronic insomnia is one of the most common sleep disorders, characterized by persistent difficulty in initiating sleep, maintaining sleep, or experiencing restorative sleep despite adequate opportunity for sleep. It affects physical health, mental well-being, cognitive performanc...

Cross-Regional Visual Reconfigurations in Contemporary Chinese Zhong Kui New Year Prints

Zhong Kui, as a deity with strong symbolic significance in traditional Chinese visual culture, continues to be reconstructed within the contemporary folk New Year print system, presenting diverse visual variations across regions. Existing studies have mostly focused on tracing th...

A COMPREHENSIVE REVIEW OF CHAVYADI GHRIT: AYURVEDIC PHARMACOLOGY AND THERAPEUTIC APPLICATION

Chavyadi Ghrit is an ayurvedic medicated herbal formulation mentioned in Bhaishajya Ratnavali for the management of anorectal and gastrointestinal diseases. The formulation comprises of herbs with properties like Deepan, Pachana, Vatanulomana, Grahi and Shoolahara. Ghee medium as...

EVALUATION OF ANESTHETIC DRUG USE IN OPHTHALMIC PROCEDURES AT PRINCE ZAID BIN AL HUSSEIN HOSPITAL

Introduction: While topical, local, and regional anesthesia are commonly used in ophthalmic surgery, general anesthesia may be necessary for children, uncooperative patients, or complex situations, selecting the incorrect anesthetic can result in systemic or ocular side effects,...