Research works

Spec-Driven Development with AI Agents: A Brownfield Walkthrough

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Bordering Sex Work: Everyday Policing and Migration Control in Zurich’s Sex Industry

Abstract Methods Using the “state from below” approach, this article examines how law enforcement operates in the context of sex work in the city of Zurich, drawing on 25 semi-structured interviews with police officers, sex workers and social workers, as well as participant obser...

A Three-Layer Dependency-and-Logic Audit for Mathematical Proofs and AI-Generated Claims: The S/M/P × D/L Framework

We introduce a structured audit framework for mathematical proofs, conjectures, and AI-generated mathematical claims. The framework operates on three layers—Semantic, Mathematical, and Programming—and for each layer examines two complementary dimensions: internal Dependency relat...

Management of pregnancy in women with transfusion-dependent β-thalassemia: An evidence-based narrative review with clinical recommendations

Abstract Transfusion-dependent β-thalassemia (TDT) is a severe hereditary hemoglobin disorder requiring lifelong regular blood transfusions, which inevitably result in iron overload and multiple organ complications. Advances in transfusion therapy, iron chelation, and multidiscip...

A status update on the coordination of flying-fox monitoring in New South Wales

Monitoring populations of flying-foxes is challenging considering their nomadic habits but is needed for conservation status assessments and tracking movement trends to inform management issues. National censuses involving synchronous counts at as many flying-fox roosts as possib...

Risk prediction and probabilistic inference of carotid atherosclerosis based on machine learning algorithms and Bayesian network analysis

Abstract Background Carotid atherosclerosis, an important subclinical manifestation of vascular injury, is closely associated with stroke, cardiovascular events, and systemic atherosclerotic burden. This study aimed to identify stable predictive factors for carotid atherosclerosi...

Behavior-Driven Development for AI: Cucumber and Gherkin Patterns for LLM Systems

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MUC5B orchestrates tobacco-driven metabolic rewiring and immunosuppression in head and neck squamous cell carcinoma

Abstract Background Tobacco exposure is a major risk factor for HPV-unrelated head and neck squamous cell carcinoma (HNSCC) and is associated with poor clinical outcomes; however, the molecular regulators through which tobacco exposure drives tumor aggressiveness and immunosuppre...

Beyond reconstruction: minimally invasive aesthetic and regenerative medicine in postoperative oral and maxillofacial surgery

Abstract Purpose Oral and maxillofacial reconstruction restores anatomical continuity and function after tumor resection, trauma and congenital deformity, yet patients frequently remain affected by fibrosis, scar tethering, impaired oral competence, asymmetry and altered dynamic...

Association between the 2022 FIFA world cup and pediatric emergency department attendance during a winter respiratory virus surge: a retrospective multicenter study

Abstract Background Escalating pediatric emergency department (PED) visits raise concerns about crowding and low-acuity attendance. We aimed to assess whether live broadcasts of the 2022 FIFA World Cup were associated with changes in PED attendance and left-without-being-seen (LW...

AI, Human Judgment, And Decision Reliability In High Tempo Military Operations

Artificial intelligence is increasingly embedded in modern military operations, influencing how commanders interpret sensor data, assess threats, and make rapid decisions under pressure. While AI improves situational awareness and accelerates operational tempo, it also introduces...

Community Connectedness and Its Association with Stigma and Viral Suppression Among MSM with HIV: Findings from HPTN 078

Abstract Gay, bisexual, and other men who have sex with men (MSM) continue to be disproportionately affected by HIV in the United States, with viral suppression rates among MSM across varied racial and ethnic groups remaining below national targets. Stigma is a major barrier to v...

Whole-Genome and Functional Potential Analysis of Pu'er Tea-Associated Heyndrickxia coagulans

This project investigates the Pu'er tea-associated strain Heyndrickxia coagulans TEA1 through whole-genome sequencing, genome assembly, structural and functional annotation, comparative genomics, and phylogenetic analysis. The study evaluates stress-response capacity, carbohydrat...

Deciphering Cellular and Spatial Regulatory Identities from Sparse Chromatin Accessibility Landscapes

Abstract Chromatin accessibility profiling provides a powerful view of regulatory landscapes across heterogeneous biological systems, enabling the investigation of cell-state diversity and spatially organized regulatory programs. However, deciphering meaningful regulatory identit...

Real-Time XAI Specifications: Performance Requirements for Production Explanations

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What a Grenade Is For: An Annotation Schema and a Pre-registered Human-LLM Test for Utility Lineups in Professional Counter-Strike

Grenade use in professional Counter-Strike follows community conventions written neither in the game's rules nor in its physics. We present an annotation schema for utility lineups, defined by an origin zone, a landing zone and a grenade type, and a de_dust2 lineup dataset built...

Counterinsurgency and Violence Against Indigenous Peoples in Chiapas (1994–1995): The Chiapas 94 Campaign Plan and the Open Investigation into the So-Called Earth-Mars Plan

This essay examines the counterinsurgency strategy deployed by the Mexican State in Chiapas between 1994 and 1995, focusing on the documented "Chiapas 94 Campaign Plan" and the unresolved question of the so-called "Earth-Mars Plan." Drawing on Inter-American Court of Human Rights...

Optimizing Antibiotic Duration for Pneumonia and Sinusitis in the Pediatric Emergency Department

OBJECTIVE Updates to national and international guidelines now recommend shortening antibiotic durations to 3 to 5 days for uncomplicated community-acquired pneumonia (CAP) and 5 to 7 days for acute bacterial rhinosinusitis (ABRS). We aimed to increase the percentage of children...

BT-PEC Theory: Analysis of Omega=0 Critical Topology and Phase Structure of Open Quantum Systems

Within a trace-class operator framework on a separable Hilbert space and based on three fundamental axioms, this paper derives the Ω = 0 steady-state condition for stable observable systems under the BT-PEC tri-coupling fundamental theory. Five classes of unstable configurations...

Exact Minimum Distance of a [[832,10]] Quantum LDPC Code: d = 15 by Exact Fold and Lift Enumeration

We determine the exact minimum distance of a two block quasi cyclic CSS code with 832 physical and 10 logical qubits. Earlier work had shown 10 ≤ d ≤ 15. We close the interval and prove d = 15. In each CSS sector the classical kernel has no nonzero word of weight 1 to 14 and exac...