Research works

PACLITAXEL-INDUCED ECZEMATOUS DERMATITIS PRESENTING AS NUMMULAR DERMATITIS: A RARE CUTANEOUS REACTION

Paclitaxel is a taxane derivative widely used in the treatment of various solid tumors, particularly breast cancer, and is associated with a range of dermatologic adverse effects. However, there are no reports in the literature describing eczematous reactions presenting in the fo...

A BASELINE MICROBIAL STABILITY EVALUATION OF GUDUCHYADI RASAYANA BY DIFFERENT MICROBIOLOGICAL TECHNIQUES ADMINISTERED IN A CLINICAL STUDY ON MENTAL WELL-BEING

Introduction: Middle-aged adults are increasingly prone to oxidative stress and deterioration in mental well-being due to aging, lifestyle modifications, and psychological stress. Guduchyadi Rasayana is a classical Ayurvedic polyherbal formulation selected as the investigational...

SCREENING FOR RISK OF HYPERTENSION AMONG THE BANK EMPLOYEES OF KALABURAGI CITY

Background: Hypertension (HTN) is a modifiable and major risk factor for coronary artery disease, heart failure, cerebrovascular disease and chronic renal failure. With sedentary lifestyles, commendable work stress, unhealthy food and personal habits these people are at a high ri...

ROLE OF KALA BASTI IN THE MANAGEMENT OF GRIDHRASI (SCIATICA): A NARRATIVE REVIEW

Sciatica is one of the most common causes of radiating low back pain and is a major contributor to musculoskeletal disability worldwide. In Ayurveda, this condition is described under Gridhrasi, a Vata-predominant, or occasionally Vata-Kapha-predominant, disorder in which pain, s...

ROLE OF ARTIFICIAL INTELLIGENCE METHODS IN BCG RESPONSE PREDICTION IN NON-MUSCLE INVASIVE BLADDER CANCER

Background: Non-muscle invasive bladder cancer (NMIBC) constitutes the majority of bladder cancer cases and is primarily treated with intravesical Bacillus Calmette-Guérin (BCG) immunotherapy. However, up to 40% of patients do not respond to BCG, highlighting the need for reliabl...

GREEN SYNTHESIS OF PYRANO [2, 3-D] PYRAZOLE DERIVATIVES USING SPINACH (SPINACIA OLERACEA) LEAF EXTRACT AS A NATURAL CATALYST: SYNTHESIS, CHARACTERIZATION, AND EVALUATION OF ANTI-DIABETIC ACTIVITY

A highly efficient, eco-friendly, and straightforward multi-component synthesis of biologically potent pyrano [2, 3-d] pyrazole derivatives (4a–4j) has been developed using an aqueous extract of fresh spinach leaves (Spinacia oleracea) as a natural, recyclable, and biodegradable...

ANALYTICAL METHOD DEVELOPMENT AND VALIDATION OF FAMOTIDINE: REVIEW

Analytical method development and Validation are the continuous and inter-dependent task associated with the research & development, quality control and quality assurance departments. Analytical procedures play a critical role in equivalence and risk assessment, management. It he...

DELAYED VACCINATION AND ASSOCIATED FACTORS AMONG CHILDREN LESS THAN 2 YEARS IN A SAMPLE ATTENDING PRIMARY HEALTH CARE CENTERS IN BAGHDAD CITY

Background: Vaccination is one of the most cost-effective preventive interventions, helping to prevent 2–3 million deaths per year; however, infectious diseases still affect Iraqi children, even though they receive vaccines free of charge. Objectives of study: To determine the ra...

RECURRENT POST-TRANSPLANT COMPLICATIONS CULMINATING IN MYCOPHENOLATE MOFETIL-INDUCED COLOPATHY IN A YOUNG RENAL ALLOGRAFT RECIPIENT: A CASE REPORT

Gastrointestinal complications are common after renal transplantation and pose a diagnostic challenge because infective, drug-induced, and rejection-related causes overlap in presentation. We report a 26-year-old female who underwent live-related renal transplantation (mother don...

A CASE STUDY: EFFICACY OF TAKRARISHTA IN THE MANAGEMENT OF ABHYANTAR ARSHA (INTERNAL HAEMORRHOIDS)

Background: Arsha (haemorrhoids) is a common anorectal disorder afflicting mankind, classified among the Ashta Maharogas due to its chronicity and difficulty in management. Ayurveda emphasizes Aushadha (medication) as the first line of treatment to correct the underlying Agnimand...

QUANTIFICATION OF CARBON DIOXIDE EMISSIONS FROM DIESEL-POWERED ELECTRICITY GENERATOR USING THE IPCC FUEL CONSUMPTION-BASED EMISSION FACTOR METHOD

The widespread use of diesel-powered generators as alternative electricity sources in higher institutions across developing countries has increased significantly due to unreliable public power supply. While these generators ensure energy availability, they are major contributors...

CLEANING VALIDATION- CHALLENGES, ACCEPTANCE CRITERIA AND REGULATORY COMPLIANCE: A REVIEW ARTICLE

Cleaning validation is a critical component of pharmaceutical manufacturing that ensures equipment and production systems are consistently cleaned to predetermined acceptable levels, thereby preventing cross-contamination and ensuring product quality, safety, and regulatory compl...

COMPARATIVE ANALYSIS OF UROPATHOGEN PREVALENCE AND ANTIBIOTIC TREATMENT PATTERNS IN E. coli VERSUS non-E. coli URINARY TRACT INFECTIONS AT A TERTIARY CARE CENTRE IN SOUTH INDIA

Urinary tract infections (UTIs) cause substantial morbidity globally, and rising multidrug resistance complicates empirical therapy. Local data on uropathogen prevalence and antibiotic prescribing is vital for stewardship. Aim: To determine the prevalence of causative uropathogen...

ROLE OF KAYAKARPAM DRUGS IN THE MANAGEMENT OF MALE INFERTILITY: A REVIEW FROM THE ANNAMAYA KOSAM PERSPECTIVE

Background: Male infertility is an increasing health concern worldwide with Siddha system of medicine offering a unique holistic approach through Kayakarpam (rejuvenation therapy) drugs. In Siddha philosophy, the human body is conceptualized through the Panchakosam theory, wherei...

ANUVĀSANA BASTI IN THE PREPARATION FOR SUKHAPRASAVA: A CRITICAL REVIEW

The third trimester is a crucial period of fetal growth, cervical maturation, increasing pelvic pressure and preparation for labour. Ayurveda describes Garbhini Paricharya for maintaining maternal and fetal health and promoting Sukhaprasava. In the ninth month, Acharya Charaka re...

LIFESTYLE MODIFICATION, SLEEP HYGIENE AND PHARMACOTHERAPY OF CHRONIC INSOMNIA

Chronic insomnia is one of the most common sleep disorders, characterized by persistent difficulty in initiating sleep, maintaining sleep, or experiencing restorative sleep despite adequate opportunity for sleep. It affects physical health, mental well-being, cognitive performanc...

THERAPEUTIC EFFECT OF YUSHA KALPANA AND LIFESTYLE MODIFICATION IN AMLAPITTA: A CASE REVIEW

In today’s lifestyle, the improper diet habit, stress, spicy irritant food, oily food, alcohol beverages etc play an important role in etiopathogenesis of Amlapita, a chronic recurring annavahastrotasroga. Amlapita is primarily characterized by aruchi(anorexia), utklesh(nausea),...

MACROSCOPIC EVALUATION OF THE IDENTITY OF VIDANGA, ITS ADULTERANTS AND MARKET SAMPLES

Plant occurs wild in Assam, Meghalaya and other provinces in North-East region of country. A large scandent shrub, branches long slender, terete, with long internodes, the bark studded with lenticels. Leaves coriaceous, fruit berries (globose) 3-4 mm diameter, smooth, succulent,...

HIDDEN POLLUTION IN IRRIGATION SYSTEMS: MICROPLASTICS IN SURFACE AND GROUNDWATER OF THE PAZHAYAR RIVER BASIN, SOUTH INDIA

Microplastic (MP) contamination from anthropogenic sources has been repeatedly proposed as an environmental threat based on its possible ecological and human health impacts, due to its persistent nature. The research aimed to explore the occurrence, distribution, characteristics...

EFFECT OF CORONAL MASS EJECTIONS ON NEAR EARTH SPACE WEATHER DURING SOLAR CYCLE 25

Coronal Mass Ejections (CMEs) inject large amounts of magnetized plasma and magnetic fields into the heliosphere. CMEs play an important role in influencing space weather conditions and can affect various technological systems on Earth, including communication and navigation syst...