Research works

Streaming Molecular Dynamics Simulation Data for On-the-Fly Processing and Analysis

Abstract Only a small fraction of the data generated in state-of-the-art all-atom multimicrosecond molecular dynamics (MD) simulations is typically analyzed. With femtosecond integration steps, microsecond simulations generate billions of time steps with a complete set of atomic...

Widespread circulation of West Nile and Usutu viruses in sedentary and migratory avifauna: A two-year study (2024–2025) of active surveillance in South of France

Abstract West Nile virus (WNV) and Usutu virus (USUV) are neurotropic Orthoflaviviruses sharing a similar enzootic transmission cycle primarily involving Culex pipiens mosquitoes as vectors and birds as amplifying hosts. First identified in Africa, both viruses established endemi...

Development and comparative analysis of predictive length of stay models using machine learning in Malaysian tertiary hospitals

Abstract Hospital length of stay (LOS) is a critical indicator of healthcare efficiency and resource allocation. While predictive modelling has escalated globally, there is a notable sparsity of literature utilising large-scale, real-world data from the Malaysian public health fr...

Rate–Distortion Optimised Image Compression with Directional Intra Prediction, Adaptive Transforms and Context-Adaptive Arithmetic Coding

This paper presents a complete still-image codec built onrate–distortion (RD) optimised block coding. The design combines aquadtree partition over 16×16 to 4×4 coding units, thirty-five directionalintra prediction modes with most-probable-mode signalling, adaptiveselection betwee...

TSPO PET selectively detects the denervated skeletal muscle district remodeling after experimental peripheral nerve injury

Abstract Background Peripheral nerve injury induces inflammatory and stress-related remodeling in downstream skeletal muscle before overt atrophy develops, yet non-invasive approaches capable of detecting and anatomically localizing early muscle involvement remain limited. The 18...

Experimental investigation on the effect of thermal ageing on mechanical characteristics of polyamide12 processed using selective laser sintering

Abstract This study investigates the variation in mechanical characteristics of Polyamide-12 (PA-12) specimens on account of thermal ageing. PA-12 has high tensile strength, long life, high chemical resistance, and excellent electrical insulation elements for use in various indus...

Horizon-Like Emission from Curvature-Bound Coherence Fields

Version 2.0 is a substantive corrected revision of the original Horizon-Like Emission from Curvature-Bound Coherence Fields study. The paper investigates horizon-like emission from a deterministic, curvature-bound coherence field within the Coherence Geometry framework. A reduced...

Reproducible human reward imaging phenotypes exhibit differential sensitivity to dopamine D2 receptor antagonism

Abstract Human reward processing varies along cue-centric and outcome-centric axes, but a reproducible mechanistic account of individual variation in incentive salience attribution has been lacking. Using fMRI across five cohorts (N-total=1,251; N1=890; N2=245; N3=34; N4=48; N5=3...

The structure of infrastructure adoption: competition of hydrogen and electric for long-haul freight decarbonization

Long-haul freight decarbonization requires deploying hydrogen refueling stations (HRSs) across networks designed around incumbent diesel supply. Existing planning tools treat node-level demand as uniform, ignoring how it emerges from the coupling between freight flows and technol...

Modeling Higher Pairs in Spherical Mechanisms

The kinematics of spherical mechanisms (SMs) shares many features with that of planar mechanisms (PMs). Specifically, both types of mechanisms can be studied by projecting their geometry onto a reference surface: a plane (the motion plane) for PMs and a sphere (the reference sphe...

Pixel-Level Sentinel-2 Modeling Reveals Scale-Dependent Edge Effects and Structural Heterogeneity in Semideciduous Seasonal Forest Fragments of the Brazilian Cerrado

Forest edge effects are commonly interpreted as radial gradients from the edge toward the interior, but this assumption may oversimplify the spatial organization of heterogeneous tropical forest fragments. Here, we integrated field-based phytosociological data with Sentinel-2 spe...

Sensitivity Analysis of Perceptual Stabilization under Historical Compression

This paper examines parameter sensitivity in a toy computational realization of perceptual stabilization under historical compression. The analysis varies state coordinates, coupling coefficients, thresholds, and selector–dominance relations while preserving the declared computat...

Conjunctive dynamic searchable symmetric encryption

Abstract A practical searchable symmetric encryption (SSE) should allow users to privately store documents on untrusted servers with the abilities to (1) search with multiple keywords, and (2) add or delete documents dynamically. The oblivious cross tag () construction from Crypt...

Sequence-defined Digital Bottlebrush Polymers for Programmable Oligonucleotide Delivery

Oligonucleotide therapeutics hold transformative potential, yet their clinical translation is hindered by delivery barriers, including rapid renal/hepatic clearance and poor organ specificity. Bottlebrush polymers conjugates have emerged as a promising vector to address these lim...

Hybrid Integral Transform Solution of a Nonlinear Core-Flooding Model with Capillary Pressure and End Effects

Abstract Oil-water displacement in coreflooding experiments is governed by a nonlinear convection-diffusion equation derived from the extended Buckley-Leverett formulation that accounts for capillary pressure effects. When realistic constitutive relations are combined with nonlin...

Infection prevention and control practices among audiologists in Ghana using survey evidence, direct observation and microbial analysis

Abstract Background: Infection prevention and control (IPC) is critical in healthcare, yet the unique risks in audiology practice remain underexplored, particularly in Ghana. Audiologists use shared equipment in close patient contact, posing cross-contamination risks. This study...

Digital twin-driven edge–cloud collaborative remote fault diagnosis and intelligent predictive maintenance for critical hydropower equipment

Abstract To address the problems of lagging remote monitoring, complex fault mechanisms, and inefficient maintenance decisions for key equipment in hydropower stations, this paper proposes a remote diagnosis and intelligent maintenance method based on edge-cloud collaboration and...

Structural Frontiers in Constructed Systems: Domains of Validity and Emergent Structural Effects

ABSTRACT Persistent patterns of confinement, sensitivity to initialization and diminishing qualitative returns from increasingly sophisticated tuning strategies are widely reported across heuristic search and optimization contexts. These phenomena are commonly interpreted as algo...

High-Alkalinity Algal Cultivation with Direct Air Capture: An Economic Feasibility Analysis

Weather variability and CO2 supply costs remain key barriers to the commercial viability of algal biofuel production. Recent experimental work has demonstrated that the algae Chlorella sp. strain SLA-04 achieves high productivity in extreme alkaline growth media (pH > 10), where...

Insulin-like growth factor 1 (IGF1) over-expression on a phycocyanin carrier protein in cyanobacteria

Abstract The Insulin-like Growth Factor 1 (IGF1) is a small (~ 7.6 kDa) protein-hormone primarily generated in the liver of mammals. It has a similar structure to insulin, and functions to support cell growth and development. As a result, IGF1 is in high demand in the biopharmace...