Research works

Oral health disparities and social determinants in Cameroon: a scoping review

Abstract Background Oral health disparities represent a major but under-prioritized public health challenge in Cameroon. Despite a growing burden of caries, periodontal disease, and tooth loss, oral health remains marginalized within national policy. Understanding the social dete...

Mechanisms of Public Service Motivation Development Through Public Administration Education: A Four‐Year Panel Study in Taiwan

ABSTRACT Given that public human capital is critical to sustainable development, this study aims to investigate the mechanisms through which public administration education shapes the public service motivation of prospective civil servants, in either positive or negative ways. Da...

LAB #1842 NEUTRAL: LEDGER BENCH: Apply filter: Pool density HIGH (>=90) — improves win rate from 32.0% to 33.6% (+1.6pp — E8 Intelligence Research

IDEA: Adjustment made to the live model — verify against the backtests: Apply filter: Pool density HIGH (>=90) — improves win rate from 32.0% to 33.6% (+1.6pp, n=1348) SAME-WINDOW EFFECT: Applying the pool-density filter (≥90) would have excluded the three rizzy5m XAUUSD shorts a...

SPECT/CT confirms metastatic pulmonary calcification on bone scintigraphy: Directing management in a dialysis patient

We report a case of metastatic pulmonary calcification diagnosed by 99m Tc-MDP bone scintigraphy with SPECT/CT in a 52-year-old man with end-stage renal disease on hemodialysis. The patient presented with bone pain and mild cough, and had severe biochemical derangements of chroni...

The Imprinted Curvature Hypothesis

The Imprinted Curvature Hypothesis (ICH) is formulated as a restricted cosmological initial-condition hypothesis within unmodified General Relativity. It introduces no new gravitational dynamics or matter sector, but specifies a weak, coherent, ultra-long-wavelength component of...

The Sixth Element: Intelligence - Proof of Concept

The Sixth Element is not a speculation. It is a measurable property of coupled oscillatory systems, formalized as I(S,T)I(S,T), and empirically validated through the deepest evidence cascade in computational physiology. "Intelligence is not what a brain does. It is what any suffi...

2-Parity Conjecture Proven for Isomorphic 2-Torsion Elliptic Curves — E8 Intelligence Research

FINDING: The 2-parity conjecture is proven for elliptic curves with isomorphic 2-torsion, linking analytic root numbers to algebraic ranks mod 2. | MATH: Let \(E_1, E_2/\mathbb{Q}\) with \(E_1[2] \cong E_2[2]\) as Galois modules. The theorem states: \(W(E_1) = W(E_2) \implies \te...

The Average-Fit Loss: A Unifying Metric for the Cost of One-Size-Fits-All Systems

Products, models, and policies are routinely optimized for a representative or average member of the population they serve. We define the Average-Fit Loss (AFL), a population-level functional that quantifies the utility forgone when a single design tuned to the center of a hetero...

ARTIFICIAL INTELLIGENCE AND DIGITAL TWIN TECHNOLOGY IN POLYMERIC NANOSPONGES: CONVERGENCE, APPLICATIONS, AND FUTURE DIRECTIONS

The polymeric nanosponges, which are hyper-cross-linked three-dimensional nanostructures, have progressed from a laboratory curiosity to a platform for delivering drugs, decontaminating environments and formulating cosmetics in the last 20 years. It’s their porous, cage-like stru...

Blood Glucose Forecasting on OhioT1DM: Evaluation-Protocol Effects, Tree Baselines, and Limited Incremental Predictive Value of Heart Rate

The forecasting accuracy on the OhioT1DM benchmark for blood glucose varies widely between reports, and differences in the evaluation protocols employed limit comparability across studies. Using the six participants of the 2018 cohort, this study held one gradient-boosted tree co...

Variations on a Mind: Substrate Bias, Cognitive Convergence, and Emergent Inheritance

Abstract Cognitive similarities between biological and digital systems are often treated with suspicion. When an artificial system exhibits attention, memory integration, salience, self-modeling, recursive interpretation, or persistent relational organization, resemblance to biol...

EuroMillions Breakthrough Mining — 3378 Sources, 29332 Leads Extracted — E8 Intelligence Research

Mined 3378 lottery+quantum breakthroughs. Extracted 29332 leads across 13 categories. 26915 high-value leads found. Categories: {"CORRIDOR": 2498, "FORMULA": 2324, "GEOMETRIC": 953, "FORWARD_ATTEMPT": 2651, "QUANTUM": 2878, "TIMING": 298, "CELESTIAL": 2407, "GEMATRIA": 2540, "CON...

Dual GLP-1/glucagon receptor agonists in metabolic dysfunction–associated steatotic liver disease: a meta-analysis of randomized controlled trials

Metabolic dysfunction–associated steatotic liver disease (MASLD) affects approximately one-third of the global population. We aimed to evaluate the efficacy and safety of dual glucagon-like peptide-1 and glucagon receptor agonists (GLP-1/Gcg RAs) in patients with MASLD. PubMed, W...

Novel Compound Heterozygous STK4 Variants Associated with Combined Immunodeficiency, Impaired Thymic Output, and Altered FOXO1-BACH2 Signaling

Serine/threonine kinase 4 (STK4) deficiency is a rare combined immunodeficiency (CID). This study aims to analyze the clinical and immunological characteristics of a child carrying novel compound heterozygous STK4 variants and to explore potential alterations in FOXO1-BACH2 signa...

New Mechanism for the String Like Debris Effect of Stars Consumed by Black Holes

The traditional Tidal Disruption Event (TDE) theory holds that when a star approaches a black hole, the tidal gravitational gradient of the black hole exceeds the star self gravity, directly tearing apart the solid star and producing elongated material streams. This physical mode...

A finite-color partition relation for $\omega_1^2$ under $\mathrm{MA}_{\aleph_1}$

We prove that, assuming $\mathrm{MA}_{\aleph_1}$, for every finite $k\ge 1$,\[\omega_1^2 \to (\omega_1\omega, \underbrace{3,\ldots,3}_{k})^2_{k+1}.\]This gives a conditional affirmative answer to Erd\H{o}s Problem \#1171.The main ingredient is a general color-reduction lemma: if...

YOLO-CSL: a lightweight real-time fabric defect segmentation network for industrial detection

To address the challenges of fabric defect detection and segmentation under complex textured backgrounds, including the fragmentation of continuous defects (e.g.broken yarns and scratches), frequent false and missed detections induced by strong texture interference, inaccurate de...

Axiodynamics Formal Kernel – Part I: Canonical Constitution and Verified Issues Register

This document is Part I of the Axiodynamics Formal Kernel. Its function is constitutional rather than expository: it fixes what the programme's six constitutive axioms commit to, records the status of every non-canonical claim attached to them, and corrects a small number of form...

Detecting and characterizing restricted diffusion with accessible magnetic field gradients

Abstract For over 50 years, diffusion magnetic resonance (dMR) has been employed in numerous studies on characterizing chemical compounds, porous media, and biological tissues. These studies have almost exclusively employed the Stejskal-Tanner (ST) pulse sequence, which is sensit...

Exploring the Quantum Chemical and Inhibitory Footprint of Coumarin Derivatives Against α-Amylase: A Unified in Silico and ADMET Profiling Study

Abstract Diabetes mellitus is a prevalent metabolic disease associated with persistent elevation of blood glucose and represents a significant challenge in the search for effective and well-tolerated therapeutic agents. Targeting α-amylase, a key enzyme involved in the hydrolysis...