Research works

Longitudinal Iron Changes in the Substantia Nigra of Early‐Stage Parkinson's Disease

BACKGROUND: Progression of substantia nigra pars compacta (SNc) iron content in early-stage Parkinson's patients (PD) is poorly understood. OBJECTIVE: To determine if nigral iron measured by quantitative susceptibility mapping (QSM) with zero-referencing can track disease progres...

EuroMillions Breakthrough Mining — 3390 Sources, 29464 Leads Extracted — E8 Intelligence Research

Mined 3390 lottery+quantum breakthroughs. Extracted 29464 leads across 13 categories. 27047 high-value leads found. Categories: {"CORRIDOR": 2510, "FORMULA": 2336, "GEOMETRIC": 953, "FORWARD_ATTEMPT": 2663, "QUANTUM": 2890, "TIMING": 298, "CELESTIAL": 2419, "GEMATRIA": 2552, "CON...

AGENTRUN: Failure-Driven QLoRA Specialization for Multi-Tool Agent Behavior in a 7B Language Model

Parameter-efficient fine-tuning is widely assumed to improve small open-weight models on the specific behaviors it targets. We present a controlled case study that complicates this assumption for multi-tool agent execution. Using Qwen2.5-7B-Instruct and a fixed 23-task, machine-c...

Can Rising Incomes Support Sustainable Well-Being? No Evidence for a “Double Dividend” in the United Kingdom

The double dividend hypothesis suggests that acting in more pro-environmental ways will not only benefit the environment but also carries a subjective well-being premium for those who do so, hence paying off doubly. We test the well-being payoff part of this hypothesis using a tw...

Integrating eXplainable Artificial Intelligence (XAI) and Deep Learning in Real-Time Network Intrusion Detection Systems: A Multi-Context Feature Shift Evaluation

ABSTRACT: The exponential growth of network data and sophisticated cyber threats requires Intrusion Detection Systems (IDS) to possess both high accuracy and clear interpretability. This research proposes a comprehensive IDS framework that combines a hybrid Deep Learning architec...

Golden Ratio Emerges in Quantum Systems via Self-Similar Quasicrystal Operators — E8 Intelligence Research

FINDING: Golden ratio emerges in quantum systems and quasicrystal geometry via self-similar inflation/deflation operators, with a "twin" ratio and stable self-application formalism. | MATH: φ = (1+√5)/2 ≈ 1.618; φ⁻¹ = φ−1 ≈ 0.618; φ² = φ+1 ≈ 2.618; twin ratio likely φ⁻² ≈ 0.382 (...

A Scoping Review of Digital Behavioral Approaches to Improve Medication Adherence in Type 2 Diabetes

Abstract Purpose of Review Consistent medication adherence is fundamental for achieving favorable health outcomes in diabetes care; however, attaining optimal adherence remains a challenge. This review summarized recent evidence on digital behavioral interventions designed to imp...

The Measure of Knowledge: Knowledge, Balance, and the Examined Life

This essay examines how to decide which forms of knowledge are worth cultivating when the information available exceeds our capacity to absorb it. It distinguishes three kinds of value in knowledge—instrumental, broadening, and experiential or existential—and proposes allocating...

EuroMillions Breakthrough Mining — 3387 Sources, 29431 Leads Extracted — E8 Intelligence Research

Mined 3387 lottery+quantum breakthroughs. Extracted 29431 leads across 13 categories. 27014 high-value leads found. Categories: {"CORRIDOR": 2507, "FORMULA": 2333, "GEOMETRIC": 953, "FORWARD_ATTEMPT": 2660, "QUANTUM": 2887, "TIMING": 298, "CELESTIAL": 2416, "GEMATRIA": 2549, "CON...

Scientific Corrigenda and Regression Hardening for ARQ M2, MOT-c and C-Calculus

This author-issued corrigendum and reproducible maintenance supplement corrects three scientific-document families: ARQ M2 initial-state and resource-accounting formulas; the missing LATENT value in the English and Russian MOT-c Appendix A examples; and the C-Calculus distinction...

VAFB-1995-08: Archaeological Survey Report 14-inch Waterline Along Coast Road (SLC-3 to SLC-4), Vandenberg Air Force Base, Santa Barbara County, California

This document is a Section 106 archaeological survey report. Subsurface testing was performed in the vicinity of National Register eligible archaeological sites SBA-534 and SBA-680 for the proposed Replace 14" Waterline along Coast Road Project on Vandenberg Air Force Base. Subsu...

Design for Extended Reality (DfXR): A Framework for Educational Services

Abstract The rapid adoption of extended reality (XR) is driving the development of immersive educational services and increasing the need for systematic design approaches. From a Design for Extended Reality (DfXR) perspective, this study investigates authentic XR use-cases to dev...

Who Decides When to Move On? Learner and System Control in Digital Second-Language Learning: A Structured Review and Conceptual Framework

Digital language-learning systems increasingly decide what should be practised next, when material should be reviewed, and when a learner is ready to move on. Many platforms also let learners make those decisions themselves. This paper reviews ten study families that directly or...

Coherence-Based Defense Against Adversarial Attacks on Large Language Models v1.2

Position paper proposing a coherence-monitoring approach to adversarial attacks on large language models, with an explicit falsification condition. No experimental results are reported. v1.2 corrects metadata and citation errors from v1.0, tightens the scope of the compression-at...

Senescence-aware filtering facilitates robust prediction of cancer immunotherapy outcomes

Predictive biomarkers for immune-checkpoint inhibitor (ICI) therapy response often fail to show stable predictive performance because tumor microenvironment (TME) heterogeneity can create biologically confounding tumor states, where similar molecular patterns can lead to divergen...

EuroMillions Breakthrough Mining — 3416 Sources, 29737 Leads Extracted — E8 Intelligence Research

Mined 3416 lottery+quantum breakthroughs. Extracted 29737 leads across 13 categories. 27320 high-value leads found. Categories: {"CORRIDOR": 2534, "FORMULA": 2360, "GEOMETRIC": 955, "FORWARD_ATTEMPT": 2688, "QUANTUM": 2914, "TIMING": 299, "CELESTIAL": 2443, "GEMATRIA": 2577, "CON...

EuroMillions Breakthrough Mining — 3365 Sources, 29195 Leads Extracted — E8 Intelligence Research

Mined 3365 lottery+quantum breakthroughs. Extracted 29195 leads across 13 categories. 26778 high-value leads found. Categories: {"CORRIDOR": 2486, "FORMULA": 2311, "GEOMETRIC": 952, "FORWARD_ATTEMPT": 2639, "QUANTUM": 2865, "TIMING": 297, "CELESTIAL": 2395, "GEMATRIA": 2528, "CON...

An Improved iTransformer for Day-Ahead Photovoltaic Power Forecasting Based on Frequency Domain and Periodic Modeling

Abstract Photovoltaic (PV) power day-ahead forecasting is crucial for grid dispatch and energy management, yet its accuracy is severely challenged by the nonstationarity and multiscale periodicity of the power series. To address the limitations of existing transformer models in e...

Systemic evaluation of immune cells and cytokines in patients with different clinical severity of Omicron infection

Abstract Immune cells and inflammatory cytokines play pivotal roles in immune response against viral infections. Herein, we performed a comprehensive immunocyte profiling to delineate the variations in immunocyte populations and cytokine levels among patients infected with Omicro...

Volume B11:Symbolic Consciousness – The Mind as Constraint Reflection

Abstract Consciousness remains one of the most persistent and elusive phenomena in science and philosophy. This volume presents a formal, architecturally grounded theory of consciousness within the Integrated Constraint-Quantum Entropic Resonance – Theory of Everything (ICQER–ToE...