Research works

Organ and tumor dosimetry of [161Tb]Tb-PSMA-617 radioligand therapy in patients with mCRPC

Abstract Purpose Terbium-161 ( 161 Tb) has emerged as a promising radionuclide for radioligand therapy (RLT) due to its emission of Auger and conversion electrons, which may support therapeutic efficacy through increased local energy deposition. Despite growing research efforts a...

Alveolar Bone Regeneration Using 3D‐Printed, Patient‐Specific, Resorbable PCL Scaffold: Prospective Cohort Study

ABSTRACT Aim To evaluate clinical feasibility of 3D‐printed, patient‐specific, polycaprolactone (PCL) resorbable scaffolds for staged alveolar ridge augmentation. Materials and Methods Ten patients requiring staged bone augmentation underwent digital planning to virtually reconst...

Circular Consumption and Sustainability Transitions: Why Favorable Product Experiences Do Not Always Generate Advocacy

ABSTRACT The transition toward Sustainable Development increasingly depends on the ability of circular economy systems to prolong product lifecycles and reduce premature waste generation. However, the success of such systems relies not only on whether consumers adopt circular pro...

Generalized Zulfia Ziwave Equation Beyond Failure Domain

In Zulfia’s Certified Probability Theory (ZBPT Framework [1]), we define theFailure Domain as Df = Ω \ Dc, where Ω is the total probability space and Dc is thecertified domain with C(Dc) = 1. The classical wave equation [3] fails in Df becauseit assumes Ω = Dc. We show that failu...

Production and Characterization of a Lipopeptide Biosurfactant from Bacillus velezensis SHB.28 Using Date Syrup for Heavy Metal Removal

Biosurfactants are environmentally friendly surface-active compounds with promising applications in environmental remediation. In this study, a biosurfactant-producing bacterium, Bacillus (B.) velezensis SHB.28, was isolated from heavy metal-contaminated soil and evaluated for it...

Unsolved Mathematical Problems: Collatz, Riemann, Goldbach, and P vs NP — E8 Intelligence Research

FINDING: The corpus centers on the Collatz Conjecture, the Riemann Hypothesis, the Goldbach Conjecture, and the P vs NP problem — all unsolved, with Collatz being the most visually "simple" yet intractable. | MATH: Collatz map: \( f(n) = n/2 \) if \( n \) even, \( 3n+1 \) if \( n...

Structure and Propagation of Mesoscale Cyclonic Eddies in the Brazil–Malvinas Confluence

ABSTRACT We present a comprehensive characterization of 1386 cyclonic eddies generated in the Brazil–Malvinas Confluence (BMC) between 1993 and 2022, using satellite altimetry and the META3.2_DT eddy trajectory atlas. By isolating locally generated cyclones over a record spanning...

Evaluation of a Zika virus-like particle-based vaccine in a highly penetrant non-human primate model of congenital infection

Zika virus (ZIKV) is an arthropod-borne Orthoflavivirus that caused a major outbreak in Central and South America in 2015–16. During that outbreak, ZIKV infection during pregnancy was associated with high rates of adverse outcomes, including miscarriage and a spectrum of neurolog...

Hydrologic Change in Seasonal Flood Pulse Dynamics Influences Fish Community Composition in a Freshwater Wetland

Abstract Seasonal flooding is a defining feature of freshwater wetlands, shaping ecological dynamics and influencing community structure. In large lake systems, fringing wetlands provide critical habitat for many fish species, yet these communities remain largely understudied, pa...

Pachymic acid exhibits synergistic antitumor efficacy with lenvatinib in hepatocellular carcinoma by targeting PPARγ to inhibit glycolysis

Lenvatinib is a first-line treatment for hepatocellular carcinoma (HCC), though drug resistance may develop with long-term use. to investigate the potential of pachymic acid to enhance lenvatinib’s anti-tumor efficacy. HepG2 and LM3 cells were exposed to pachymic acid and/or lenv...

Novel Stress‐Evolution Model for NaNi 1/3 Fe 1/3 Mn 1/3 O 2 Cathodes: Determining Localized Accumulation and Diffusive Transfer Based on Tension‐Compression Asymmetry

ABSTRACT O3‐NaNi 1/3 Fe 1/3 Mn 1/3 O 2 (NFM) is a promising high‐energy‐density cathode for sodium‐ion batteries. However, the long‐term cycling performance is hindered by particle fracture caused by non‐uniform stress distribution. The mechanisms of non‐mechanical stress accumul...

Multimodal optical positron characterization of radiation-induced defects and their evolution in β-Ga2O3

Abstract Gallium oxide (Ga 2 O 3 ) is an emerging candidate for next-generation radiation detectors due to its ultrawide bandgap, high-temperature stability, and large breakdown field, making its radiation tolerance and defect behavior critical to advancing device performance. To...

Age- and sex-adjusted genomic differences between Korean and Beat AML cohorts

Genomic profiling plays a central role in risk stratification and therapeutic decision-making in acute myeloid leukemia (AML), yet the clinical implications of population-specific genomic architectures remain incompletely defined. We conducted a prospective, multicenter study of...

A framework-driven cross-case analysis of pedagogical innovation in Indonesian chemistry education dissertations

Purpose This study examines structural patterns in pedagogical innovation across six Indonesian doctoral dissertations, five in chemistry education and one in physics education, using the Glocal Myths-Facts Analysis Framework (GMFAF) to diagnose whether an innovation is contextua...

Ready or Hesitant? Pediatric Sedation Confidence Among Senior OMS Residents

PURPOSE/OBJECTIVES: To describe self-reported confidence of final-year oral and maxillofacial surgery (OMS) residents in managing pediatric sedation and to explore associated training-related factors. METHODS: A prospective, cross-sectional, multicenter electronic survey was dist...

Coupled analysis of tire slip and longitudinal vehicle response using a parameterized tire model under different torque conditions

This study presents a computational investigation of longitudinal tire slip dynamics and their influence on vehicle motion using a parameterized tire model within an integrated four-wheel vehicle framework. Existing analytical, reduced-order, and experimental studies frequently t...

Association between Korean medicine use and analgesic and opioid utilization among patients with gastric cancer

Abstract Background Cancer-related pain is commonly managed with analgesics, including opioids; however, concerns regarding long-term use have underscored the need for complementary approaches. This study investigated the association between Korean medicine (KM) use and subsequen...

The Carlo Continuation: Navigation, Direction, and Progress After Universal Subjectivity

This deposit contains the full sequel to *The Carlo Collapse*, extending the framework of subjective proof, subjective interpretation, and model‑dependent meaning into a complete methodology for navigating subjective fields. *The Carlo Continuation* addresses the central post‑col...

When Knowledge Production No Longer Requires Knowing: Rethinking Gewu Zhizhi (Investigating Things and Extending Knowledge) in the Age of AI

This essay reconsiders gewu zhizhi (investigating things and extending knowledge) under a technological condition in which propositions, explanations, distinctions, questions, and even apparently reflective trajectories of inquiry can be produced before an equivalent process of h...

Hierarchical versus flat machine learning model for intrusion detection in secure IoT healthcare environment

Abstract Attack surface for cyber threats in healthcare environments is expanding rapidly with the increasing adoption of Internet of Things (IoT) devices. These devices are typically resource-constrained and possess limited security features, making them highly vulnerable to a w...