Research works

Biopesticidal Potential of the Cannabis sativa L. Metabolites: A Denoised, Docking-Informed QSAR Model

Plant metabolites are a promising source of new biopesticides, but their chemical diversity exceeds the capacity of experimental screening. Cannabis sativa is a particularly attractive crop for discovering such compounds, although its metabolome has not been systematically evalua...

Impact of hormone therapy on mood in a real-world clinical setting: a retrospective observational study

Objective: Mood disturbances—including depressed mood, irritability, anxiety, and mental exhaustion—are common during the menopause transition, affecting up to 68% of women. While menopausal hormone therapy (HT) is FDA-approved for vasomotor and genitourinary symptoms, its role i...

PDMS-based flexible packaging method via a 12-inch RDL-first process for conformal electronic applications

Purpose This study aims to realize large-scale and high-density manufacturing of conformal electronic devices by proposing a polydimethylsiloxane (PDMS)-based flexible packaging method via a 12-inch wafer-level redistribution-layer-first (RDL-first) process. Design/methodology/ap...

Adaptive Path Planning and Process Optimization for FDM of Structural Components with Complex Geometric Features

Fused deposition modeling (FDM) faces significant challenges in simultaneously achieving high forming efficiency and surface quality when processing models with complex geometric features, such as multibranch structures and independent holes. This article proposes an adaptive pat...

Trauma Work with Horses: Compassion and Connection

New ways of working with trauma survivors are being sought with the case being made that dominant trauma therapies have relied too heavily on verbal narration and cognitive processing. Evidence suggests that traumatic experiences are often encoded in sensory, emotional, physiolog...

Coordinated Scheduling of Distribution Network and Transportation System for EVs with Aggregated Flexibility and Endogenous Dynamic Pricing

With the large-scale integration of Electric Vehicles (EVs) into distribution systems, the spatiotemporal uncertainty of charging loads and the interplay between user charging behavior and network operational constraints present new challenges to the safe and economical operation...

The Uncomputable Frontier: BB(5) Solved and Higher-Order Busy Beavers — E8 Intelligence Research

FINDING: The Busy Beaver function BB(n) defines the maximum steps a halting n-state Turing machine can run; BB(5) was recently resolved via collaborative proof, and higher-order oracles extend the function into uncomputable hierarchies. | MATH: BB(5) = 47,176,870 (proven 2024, Sc...

The Corridor Overlap Duality Certificate: An exact synchrony-diversification tradeoff for two shared habitat paths

Comparator-certified working-corpus methods note. This public working-corpus release includes the reviewed manuscript and paired Lean evidence. It is not peer reviewed or empirically validated; significance and novelty have not been independently established.

Are Wall Shear Stress Fluctuations the Missing Hydrodynamic Parameter in Gas-Assisted Membrane Distillation?

Gas–liquid two-phase flow is widely recognized as an effective strategy for enhancing membrane distillation (MD) performance by mitigating thermal and concentration polarization. However, most studies interpret this enhancement using time-averaged hydrodynamic quantities, such as...

Constitutive Metabolomic Profiles Linked to Seasonal Climate Niche Adaptation and Resilience to Black Rot in Cabbage

Plants are dynamic chemical factories that produce diverse specialised metabolites essential for growth, defence, and environmental adaptation. Metabolomes, shaped by genetic architecture, enable plants to respond to abiotic and biotic pressures, including temperature fluctuation...

Beyond Prevalence: An Exploratory Framework for Patient Phenotyping and Clinical Burden Analysis of Incidental Findings in Dental Cone-Beam Computed Tomography

Abstract To move beyond simple prevalence reporting by applying an exploratory, transferable multi-method analytical framework to incidental findings on dental cone-beam computed tomography (CBCT). The framework combines multiple correspondence analysis (MCA), data-driven patient...

High-dimensional inverse design enables multiple synthesis routes to prescribed carbon nanotube array descriptors

Abstract Prescribed synthesis of carbon nanotube (CNT) arrays remains challenging because multiple processing stages jointly regulate array height (H), density (ρ), and orientational order (HOF), creating a nonlinear and non-unique relationship between structural targets and synt...

Carol numbers

We present some properties of Carol numbers. We show the relationship between Carol numbers and Mersenne numbers and also between Carol numbers and other numbers. We also study the relationship between other classes of numbers, sometimes arriving at interesting hypotheses that re...

Spatial Distribution and Socio-Economic Effects of Poverty Alleviation Programmes in Ondo State, Nigeria

Poverty alleviation programmes are central to Nigeria's development strategy, yet rigorous state-level evidence on their spatial distribution and socio-economic impacts remains limited. This study addresses that gap by conducting an integrated geospatial and householdlevel assess...

The Winner Takes It All? The Impact of Mathematics Olympiad Elimination on Kazakh High-Achieving Students’ Expectancy-Value Beliefs and Career Aspirations

Mathematics Olympiads play an important role in developing mathematically gifted students, yet little research has examined how participants interpret the experience of elimination from these highly selective competitions. This qualitative study investigates how mathematically hi...

The One T: A Working Theory of a Single Experiencer

The One T is a developing philosophical theory in which T is the only ontologically independent reality and the only experiencer. What appears as a plurality of individual experiencers is modeled as a plurality of perspectives of T. The model introduces informational objects, inf...

The Trade‐Off Between Sustainability Reporting Quality and Corporate Investment Activity: Does Political Stability Matter?

ABSTRACT This paper investigates the relationship between sustainability reporting quality (SRQ) and corporate investment activity, focusing on corporate investment intensity and corporate investment inefficiency, and the moderating role of national political stability. Using a m...

Hit It before It Starts: Targeting a (3 + 1) Hybrid Non-canonical G-Quadruplex to Silence PARP1 in Cancer

Abstract Error-prone DNA repair pathways promote genomic instability and cancer progression. Notably, Poly(ADP-ribose) polymerase-1 (PARP1)-directed alternative non-homologous end joining plays a pivotal role in cancer, including Multiple Myeloma (MM), conferring vulnerability to...

The Carlo Collapse: A Formal Treatise on Subjective Proof, Subjective Interpretation, and the Emergent Multiverse of Meaning

This deposit contains the final draft of *The Carlo Collapse*, a formal–philosophical treatise demonstrating that once proof is accepted as subjective, interpretation and meaning necessarily collapse into subjectivity as well. The document establishes a complete deduction chain s...

E8 Phi-Chronon Topological Memory Lattice — E8 Intelligence Research

The 240 E8 root vectors, phase-locked at 132 Hz via phi-braiding, generate a non-Abelian Berry connection across successive 7.576 ms chronon ticks that accumulates a topological winding number in the graviton-phonon transducer's QEC cycle. This winding number acts as a geometric...