Research works

Bis-Nitrene Prevails: Ligand-Controlled Divergence from the Conventional Mononitrene Pathway in Dirhodium Catalysis

Abstract Dirhodium paddlewheel complexes are widely used in C–H amination, yet whether bis-nitrene intermediates participate in catalysis remains an open question. Through systematic DFT calculations at the M06L/dgdzvp/SMD level, we show that both axial and bridging ligands exert...

A qualitative examination of the content validity and acceptability of the EQ-5D-Y-3L and EQ-5D-Y-5L in adolescents with type 1 diabetes mellitus in Ethiopia

Abstract Background The EQ-5D-Y-3L and EQ-5D-Y-5L are widely used generic measures of health-related quality of life (HRQoL), including among children and adolescents with Type 1 Diabetes Mellitus (T1DM). However, evidence on the measures’ content validity and acceptability in lo...

Transient cartilages and interdigital vasculature organization in the embryonic duck foot

Abstract The evolution of webbed limbs represents a recurrent adaptation to aquatic life in tetrapods, facilitated by the dynamics of embryonic digit development. Digits form at the distal tip of the limb bud as cartilage condensations surrounded by mesenchymal cells, a process d...

Quadratic Sample Complexity for Strictly Replicable Realizable Learning with Unknown Marginals

Under the quantifier "there exists A for all D", where the realizable distribution and its marginal are unknown, we determine the finite-class sample-complexity exponent for strict replicability: two independent samples and one shared seed must produce identical functions. For ep...

Gastric Mucosa Cancer Risk: The Operative Link on Gastritis Assessment Staging System

Gastric mucosa atrophy is the cancerization field for gastric cancer development. Atrophic changes in the gastric mucosa can be assessed endoscopically and histologically. Gastric serology (e.g., pepsinogens and their ratio, and gastrin) may provide information on the functional...

Mortars and plasters at Herod's Caesarea Maritima: integration of imported and local construction technologies

Abstract Building materials from different architectural elements at Herodian Caesarea Maritima (22–4 BCE ) provide evidence for a variety of compositions tailored to specific construction functions, demonstrating the extent of Roman technological influence on Herod's architectur...

Molecular divergence and genomic composition of B chromosomes in the fish Cyphocharax modestus (Characiformes, Curimatidae)

Abstract B chromosomes are supernumerary elements that evolve from standard A chromosomes and are primarily composed of repetitive DNAs, yet their origin, diversification, and molecular composition remain poorly understood in most vertebrates. We investigated two allopatric popul...

Efficiency of the cationic porphyrin, TMPyP4, in inducing cytotoxicity in mouse melanoma cells in vitro : Subcellular localization and photodynamic activity

As a minimally invasive modality, photodynamic therapy achieves selective tumor eradication through the synergistic action of a photosensitizing agent, visible light illumination, and cellular oxygen. Porphyrin-based compounds remain among the most extensively studied photosensit...

Bioorthogonal Polymer Nanozymes for Effective Treatment of Bacterial Wound Biofilm Infections

Multidrug-resistant (MDR) bacterial infections are a rapidly emerging healthcare crisis. The challenge of MDR bacteria is further exacerbated through biofilm formation that limits effective drug penetration and hinders the ability of the host immune system to clear the infection....

How does nitrogen application impact soil respiration and CH4 emissions? An experiment in an oil palm plantation on tropical peat

Abstract Oil palm cultivation on peatlands causes severe environmental damage, yet its greenhouse gas (GHG) footprint and underlying biogeochemical drivers remain poorly quantified. This study assessed how nitrogen fertilizer application impacts soil respiration and CH4 emissions...

Reversing the pipeline: a ‘human-first’ multi-omics approach to cardiovascular discovery

Despite significant biomedical advances, cardiovascular disease remains a leading cause of global mortality. The traditional 'bench-to-bedside' research pipeline, which heavily relies on animal models to guide clinical translation, is often hampered by species-specific physiologi...

Association of organisational culture and internal participation with job satisfaction among physiotherapists: a cross-sectional study

Abstract This cross-sectional study aimed to examine the independent and combined relationships of organisational culture and internal participation with job satisfaction of physiotherapists. Data was collected through an online survey of licenced physiotherapists in Saudi Arabia...

An All-in-One Optical Emission Platform for On-Site Sensitive Detection of Selenium in Selenium-Enriched Food: Integrating Digestion, HS-SPME, and Microplasma OES

Abstract The narrow margin between selenium (Se) deficiency and toxicity demands rapid and reliable methods for monitoring Se levels in Se-enriched foods. In this work, we present an all-in-one optical emission platform that integrates in situ sample digestion, derivatization wit...

A Unique Operator-Topological Decomposition Framework for Lℬ-Valued General Fuzzy Automata

[Formula: see text]-valued general fuzzy automata provide a rich algebraic–topological framework for modeling systems with uncertainty and graded dynamics. This paper investigates the structural decomposition of [Formula: see text]-valued GFA through the lens of three fundamental...

Photothermal-Induced In Situ Crystallization of Perovskite Nanocrystals and the Application on Micro–Nano Defect Detection

Abstract Micro–nano defects on the optical elements are critical factors limiting the maximum light intensity tolerance and system reliability. Developing an accurate and efficient method for defect detection remains a significant technical challenge. Notably, under laser irradia...

Sustainable Au (III) adsorption using greenly Fe-BTC/PpPDA synthesized composite: kinetic and isothermal studies

Abstract A novel porous composite material, Fe-BTC/PpPDA, was synthesized via a green solvothermal route by integrating polyparaphenylenediamine (PpPDA) into the Fe-BTC metal–organic framework. The material was characterized by X-ray diffraction, FTIR, ultraviolet-visible and sca...

Persistent estrus signs in a spayed bitch following coexistence of ovarian remnant syndrome and exposure to exogenous estrogen: a case report

Ovarian remnant syndrome represents the most frequent diagnosis in young bitches that present estrous signs some time after ovariectomy/ovariohysterectomy. However, other differential diagnoses should be considered and ruled out, including exogenous estrogen exposure and hormone-...

Electric appliance usage measured by a sensor and frailty in Japan

Abstract Background The measurement of in-home activity for frailty is limited by poor adherence, recall bias in self-reported measurements, and difficulties with long-term tracking. Data on electrical appliance usage can estimate in-home activities and be measured every minute,...

Maxwell's Equations in Spherically Symmetric Black Holes with Phantom Global Monopoles

In this paper, we investigate the electromagnetic field tensor inside a spherically symmetric space-time. In particular, we are interested in a metric that describes both ordinary and phantom global monopoles in a black hole with phantom global monopoles. In this curved spacetime...

Solvent-Engineered Fe-Doped CuCo Prussian Blue Analogue Nanozyme with Enhanced Catalytic Activity for Dual-Mode Colorimetric and Electrochemical Immunoassays

Abstract Early and accurate determination of human epidermal growth factor receptor 2 (HER2) is of great significance for the diagnosis and prognosis evaluation of breast cancer. Herein, a structurally transformed Fe-doped hexagon-like CuCo Prussian blue analogue (FeCuCoPBAH) wit...