Research works

When Empiric Therapy Fails: Clinical and Economic Consequences in uUTIs Among US Women

Uncomplicated urinary tract infection (uUTI) management is increasingly challenging due to antibiotic treatment failure (TF). This retrospective, observational cohort study used Optum’s de-identified Electronic Health Record dataset (January 2017–September 2022) to investigate th...

Surface roughness characterization for hygiene tissue products via contact profilometry

Abstract Surface roughness is an important factor affecting the surface properties of hygienic tissue products. However, standardized methods for measuring the surface roughness of hygienic tissue products are lacking. In this study, a stylus-contact profilometry method was devel...

Efficient Waveform Capture without Absorption with Synthesis of Complex Frequencies

Abstract An optical waveform can be synthesized using complex-frequency waves as well as real-frequency harmonic waves. While a single complex-frequency wave with exponentially rising waveform can be perfectly absorbed in lossless structures. Here, we propose that diverse optical...

Monoclonal antibodies inhibiting MMP-9 activity alleviate peripheral neuropathy in diabetic mice

Diabetic peripheral neuropathy (DPN) is a debilitating medical condition that affects millions of individuals, causing neuropathic pain and chronic wounds. Despite its substantial impact, there are currently no effective disease-modifying treatments available to prevent or revers...

Socioeconomic inequalities in sleep disturbances among school-aged children: evidence from socioeconomically vulnerable schools

Abstract Background Family socioeconomic inequalities have been consistently associated with children’s sleep disturbances. However, it remains unclear whether these inequalities are equally evident among children attending socioeconomically vulnerable schools, where many environ...

Identifying Research Priorities for the Development of High-Integrity Forest Carbon Credits

Abstract In the United States, voluntary carbon markets have gained significant traction in recent years. However, many offset standards, protocols, and credit ratings have come under scrutiny from the public and investors for failing to produce real or sustainable carbon offsets...

A Systematic Review of AI Methods Across the MRI Analysis Pipeline for Multiple Sclerosis Progression Prediction

Magnetic resonance imaging (MRI)-based prediction of multiple sclerosis (MS) progression depends on how imaging data are prepared, represented, modelled, and evaluated. This systematic review synthesized artificial intelligence (AI) methods across the MRI-to-prediction pipeline....

Macrophage Differentiation Selectively Downregulates RPS15A While Preserving RPL13A and RPL17 Expression in THP-1-Derived Macrophages

Atherosclerosis is a chronic inflammatory condition that is considered a major contributor to cardiovascular disease (CVD). Atherosclerosis is linked to multiple risk factors, including dyslipidemia, particularly elevated levels of low-density lipoprotein (LDL), which can infiltr...

Loss of galactan synthesis in pea (Pisum sativum) causes defects in organ expansion and is associated with increased extensin content

Abstract Pectic galactan is a rhamnogalacturonan-I side chain, composed of β-(1→4)-linked D-galactose residues. Its multifunctional role in cell wall assembly and properties has been proposed in various developmental contexts. In this study, we investigated the role of galactan i...

VAFB-1994-14: The Archaeological Evaluation of Site CA-SBA-2446 for the Titan Fiber-Optic Transmission System Vandenberg Air Force Base, Santa Barbara County, California.

This document is an archaeological evaluation that was conducted on archaeological site CA-SBA-2446 by the Cultural Resources Division of Parsons Engineering-Science, Inc. This evaluation was conducted in support of the proposed Titan Fiber-Optic Transmission System (TFOTS) for V...

The Mathematics of Why a Dried Goat Turd Makes a Terrible Boomerang — A Complete Failure Analysis of Pellet-Based Aerodynamics

This work presents the first fully rigorous mathematical proof that a dried goat turd (denoted G) cannot, under any physically admissible throwing configuration, execute a returning boomerang trajectory. Building on nonlinear dynamics, brittle-fracture mechanics, stochastic geome...

Philosophical Buddhism and fundamental reality: a reply to McNabb and Baldwin

Abstract Tyler McNabb and Erik Baldwin argue that (among other Asian traditions) Buddhism is logically consistent with the existence of a fundamental being of the sort in classical theism. They further contend that the Jonang-Zhentong (Shentong) and Jodo Shinshu (Shin) Buddhist t...

Antibody-Based Therapeutics in Autoimmune Diseases: Mechanisms, Challenges, and Future Perspectives

Autoimmune diseases encompass nearly 100 distinct conditions characterized by dysregulated immune responses against self-antigens, resulting in tissue damage, chronic inflammation, and substantial morbidity. Over recent decades, the global burden of autoimmune diseases has increa...

Turbulence‐Intensity Effects on the Aerodynamic Performance of an H‐Type Darrieus Wind Turbine: A URANS Parametric Study

ABSTRACT The effect of inlet turbulence intensity (TI) on the aerodynamic performance of a three‐bladed H‐type Darrieus vertical‐axis wind turbine with NACA 0021 blades was investigated using two‐dimensional (2D) unsteady Reynolds‐averaged Navier–Stokes (URANS) simulations. The r...

Polyaniline-Assisting Construction of Highly Phosphomolybdate-Loading Electrode with Nano-Morphology Towards Aqueous Supercapacitor and Zinc-Ion Battery

Abstract The development of a high-mass-loading-based electrode represents a pivotal breakthrough for achieving high capacitance. Polyoxometalates (POMs) possess obvious redox activity and theoretical specific capacity, demonstrating potential value as an electrode material for a...

Chitosan–Orientin Nanoparticles Attenuate Hypoxia-Induced Pulmonary Inflammation in Rats

Background: Hypoxia triggers pulmonary inflammation and oxidative stress, leading to endothelial dysfunction, apoptosis and lung injury. Although the flavonoid orientin exhibits potent antioxidant and anti-inflammatory properties, its pharmacokinetic behavior remains incompletely...

Unmasking ESG-washing: the power of transparency and gender diversity on firm value in the energy sector

Purpose Drawing from the legitimacy and signaling theories, this paper aims to investigate the impact of environmental, social and governance (ESG)-Washing on the market value of energy companies, considering the role of the firm’s board gender diversity (BGD) and the disclosure...

Remimazolam Versus Propofol for Anesthesia with I-Gel Airway Management During Coil Embolization of Unruptured Intracranial Aneurysms: A Randomized Controlled Trial

Background: Maintaining hemodynamic stability is crucial during coil embolization of unruptured intracranial aneurysms. Remimazolam has been suggested to exert less cardiovascular depression than propofol and may therefore provide more stable hemodynamic conditions. This study co...

Influence of neighborhoods-built environment on the level of satisfaction among dwellers of a mining city in eastern India

Neighbourhood built environment plays a crucial role in shaping residents satisfaction and urban quality of life, particularly in industrial and mining cities where environmental degradation and infrastructural inequality remain major urban challenges. The study aims to evaluate...

Development and characterization of p-phenylenediamine/g-C 3 N 4 -based composite polysulfone (PSF) membranes for enhanced chromium (Cr(VI)) removal from wastewater

In this study, polysulfone (PSF)-based composite membranes were synthesised through phase inversion. These membranes were then dip-coated with non-functionalized and functionalized Graphitic Carbon Nitride (g-C 3 N 4 ) to enhance Chromium (Cr(VI)) removal from a Cr(VI)-containing...