Research works

Arterial Spin Labeling Hemodynamic Indices Relate to Cognitive and Small Vessel Disease Trajectories Over 11 Years

BACKGROUND: Hemodynamic insufficiency may contribute to the development of neuroimaging signs of cerebral small vessel disease (SVD). The arterial spin labeling (ASL) spatial coefficient of variation (ASL-sCoV) is a proxy marker of arterial transit time and may better capture SVD...

Mental health link workers in neighbourhood care: a theoretical application of the creative health communication framework

Purpose This article explores the conceptual application of the Creative Health Communication Framework (CHCF) to mental health and wellbeing support within integrated neighbourhood models of care. It proposes the introduction of specialist Mental Health and/or Creative Health Li...

Can Nonprofits Gain an Advantage in Employee Retention Through Management Practices? A Comparative Lens for Managing Nonprofit Versus for‐Profit Employees

ABSTRACT Nonprofit organizations (NPOs) face growing competition for human capital from for‐profit organizations (FPOs). However, little research adopts a comparative lens to explore management practices that are associated with an advantage in retaining employees for NPOs relati...

Industrial Expansion Without Population Retention? Planning Tensions in a Shrinking Peri-Urban Village

Population decline is reshaping rural development and requiring village planning to balance land-use efficiency with changing community needs. This study examines planning-led land-use restructuring in Gushanqian Village, a shrinking peri-urban village in Shandong Province, China...

Treatment of Licorice Wastewater via Coagulation–Flocculation and Ozonation Combination: ANN-GA Modeling and Optimization

This study aimed to remove licorice (Glycyrrhiza glabra) extract from pharmaceutical wastewater using a combination of treatment processes. An Artificial Neural Network (ANN) was coupled with a Genetic Algorithm (GA) to optimize the treatment parameters. Alum, polyaluminum chlori...

SM2-PRE+: A Lightweight Pairing-Free Proxy Re-Encryption Scheme for Secure IoMT Healthcare Data Sharing

With the rapid development of the Internet of Medical Things (IoMT), wearable sensors and intelligent medical terminals continue to generate a large amount of sensitive medical data, which needs to be uploaded to the cloud platform for storage and sharing. However, IoMT devices u...

Combining Formal Reasoning and LLMs for Scenario-Based Educational STEM Exercises

Abstract Large language models (LLMs) enable scalable generation of educational exercises for science, technology, engineering, and mathematics (STEM) but often produce mathematically invalid or physically inconsistent problems, while manual authoring remains accurate but hard to...

Ce-promoted CaO for hydrogen production in sorption-enhanced biomass gasification

CaO sorption-enhanced biomass gasification (SEBG) enables in situ CO 2 capture and hydrogen production; however, CaO-based materials often suffer from performance loss during repeated operation. In this work, Ce-promoted CaO-based materials were prepared by introducing different...

The Physics of Formal Logic: The Arithmetic Foundations of Quantum Operators and the Retirement of Platonic Abstraction

Abstract For centuries, the platonic paradigm of pure mathematics has treated numerical structures as abstract inventions of the mind, isolated in a logical vacuum and divorced from physical constraints. This isolation has led to systematic conceptual failures, where the infinite...

Data-driven perimeter control: A Zürich case study

Urban traffic congestion is a key challenge for the development of modern cities, requiring advanced control techniques to optimize existing infrastructure usage. Despite the extensive availability of data, modeling such complex systems remains an expensive and time-consuming ste...

Metagenomic Insights into Microbial Functional Potential Associated with Soil Carbon, Nitrogen, and Phosphorus Cycling Along an Elevational Gradient in a Warm-Temperate Forest

Soil microbial functional potential is crucial to maintaining forest productivity and ecosystem functions. However, how microbially mediated soil nutrient cycling responds to environmental changes, particularly those caused by variations in elevation, remains poorly understood. U...

Temporal lymphatic tissue destruction and impairment of de novo T cell responses after an acute virus infection

Abstract Post-acute infection sequelae (PAIS), which include diverse immunological alterations and clinical syndromes, represent a significant yet poorly understood phenomenon following acute viral infections. While the host typically resolves acute infections within weeks and de...

Neutropenic Diet Versus Liberalized Diet in Patients With Cancer: A Systematic Review and Meta-Analysis

Purpose Neutropenic diet (ND) has historically been recommended to reduce infectious complications in patients with cancer. Although its use has declined over the past decade, recent studies, particularly in patients undergoing hematopoietic stem-cell transplantation (HSCT), have...

Multi-process regulation of surface residual stress for improving SCC resistance of Al-Zn-Mg-Cu alloy high-lock nuts

Aerospace high-lock nuts, as core aircraft fasteners, face severe stress corrosion cracking (SCC) risks during long-term service, threatening flight safety. This study investigates the effects of closing, stress relief aging and shot peening on residual stress, SCC resistance and...

"Extraordinary claims require extraordinary evidence" – proactively evidencing research software impact

As RSEs, at some point we may need to provide evidence that our software actually has some effect on the world. Whether this is for career progression, the REF, just for your own peace of mind, collecting usage data takes many forms but can often come as an afterthought. In this...

Novel mutations of PIKFYVE identified in 322 sporadic cataract patients

BACKGROUND: PIKFYVE, a novel pathogenic gene causing congenital cataract, its association with sporadic cataracts has not been systematically investigated. This study aimed to explore PIKFYVE mutation profiles in major sporadic cataract subtypes. METHODS: We enrolled 322 sporadic...

Progressive Structural Failure in Complex Prosthetic Joint Infection Followed by Amputation

Background: Prosthetic joint infections (PJI) are complex complications of arthroplasty. Detailed sequential polymicrobial infection during long clinical courses, with multiple interventions and sustained antibiotic pressure, has been described sparingly. Methods: We present a ca...

Microalgae for biohydrogen production: technological advancement, economic potential, and sustainable energy solutions

Microalgae are promising renewable resources for sustainable hydrogen production, offering a pathway towards carbon-neutral energy systems and supporting the Sustainable Development Goals (SDGs). Biohydrogen production occurs through hydrogenase- and nitrogenase-mediated pathways...

Outcomes of CHOP versus CHOEP/EPOCH in aggressive adult T-cell leukemia/lymphoma: an international cohort analysis

Aggressive adult T-cell leukemia/lymphoma (ATL) subtypes (i.e., acute and lymphomatous) are rare diseases, and the conventional management with cyclophosphamide, doxorubicin, vincristine, and prednisone (CHOP) has historically yielded poor outcomes. The benefit of etoposide-conta...

A Dual-Physics-Informed Neural Network with Incremental Learning for Corrosion Fatigue Crack Growth Prediction in Aluminum Alloys

Aluminum alloys used in aircraft structures are susceptible to corrosion fatigue cracking under combined aggressive environments and cyclic loading, threatening structural integrity. Pure data-driven models often fail under distribution shifts, while single-physics-informed neura...