Research works

Exploring the Role of Hyperfocus in the Psychophysiology of Probable Bruxism and Painful Temporomandibular Disorders

ABSTRACT Background Bruxism and temporomandibular disorders (TMD) are multifactorial conditions in which cognitive and behavioural traits may play an underrecognised role. Hyperfocus, defined as intense and sustained attentional engagement, has been proposed as a potential driver...

Effect of Abrocitinib on the Skin Microbiome in Patients With Moderate‐to‐Severe Atopic Dermatitis

BACKGROUND: Atopic dermatitis (AD) is characterized by microbial dysbiosis, notably an overabundance of Staphylococcus species. This study aimed to evaluate the effects of abrocitinib, a Janus kinase 1-selective inhibitor, on the skin microbiome and clinical outcomes in patients...

Personal Names as Repositories of Communal History and Circumstance among the Igala People of Kogi State

Abstract Personal names among African communities function as durable instruments of memory, holding within a single word the conflict, migration, reconciliation and communal occurrence that shaped the moment of a child's birth; this premise underlies the paper, Personal Names as...

EuroMillions Breakthrough Mining — 1220 Sources, 7722 Leads Extracted — E8 Intelligence Research

Mined 1220 lottery+quantum breakthroughs. Extracted 7722 leads across 13 categories. 5875 high-value leads found. Categories: {"CORRIDOR": 613, "FORMULA": 473, "GEOMETRIC": 657, "FORWARD_ATTEMPT": 638, "QUANTUM": 849, "TIMING": 169, "CELESTIAL": 559, "GEMATRIA": 597, "CONSTANT":...

Generative Geometry: From Operational Set Theory to Emergent Space

We develop generative geometry, a formal framework in which space, metrics, and invariants are not postulated but emerge from the operational primitives of Operational Set Theory (OST) and a single ontological axiom of non-annihilable change. In Part I, we construct an ontologica...

Response of maize root endophytes to carbon-nitrogen coupling in the irrigated area of the West Liaohe Plain, Inner Mongolia

Abstract Stover return and nitrogen management are key agricultural practices influencing crop root-associated microbial communities. However, how their coupling affects the community structure, absolute abundance, and functional potential of maize root endophytes remains poorly...

EuroMillions Breakthrough Mining — 1221 Sources, 7733 Leads Extracted — E8 Intelligence Research

Mined 1221 lottery+quantum breakthroughs. Extracted 7733 leads across 13 categories. 5886 high-value leads found. Categories: {"CORRIDOR": 614, "FORMULA": 474, "GEOMETRIC": 657, "FORWARD_ATTEMPT": 639, "QUANTUM": 850, "TIMING": 169, "CELESTIAL": 560, "GEMATRIA": 598, "CONSTANT":...

VES MaxEnt Neuromorphic Processor: A Physical Reaction - Diffusion Computer for Generative AI

We present the design of a novel analog neuromorphic processor – the VES MaxEnt Neuromorphic Processor – whose computational dynamics are derived directly from the statistical mechanics of an overdamped threshold medium with an exponential distribution of critical thresholds. Thi...

MODEL ADOPTION #579: REJECT — TG AUTO: BASE 44 ORDER: Implement Q8-CLUSTER-098 geometric compression in E8 pipeline — E8 Intelligence Research

DECISION: REJECT ELEMENT: Q8-CLUSTER-098 geometric compression at ratio 0.753 fails the hostility filter — it is a fixed scalar applied *before* phi-harmonic extraction, which violates E8's sacred geometry timing principle. The phi-harmonic extraction is already the noise filter;...

Navigating the Role of Radiotherapy for Extremity Soft Tissue Sarcomas

Background/Objectives: The basis for treatment of sarcoma is surgical resection. However, since the introduction of limb salvage surgery, guidelines recommend radiation as a complement to surgery for high-grade sarcomas. The aim of the present narrative review was to provide a co...

Sleep MAPP: a decision support tool for guideline-concordant sleep care in the polytrauma/traumatic brain injury system of care

OBJECTIVE: First, to summarize the development of Sleep MAPP, a decision support tool designed to facilitate guideline-concordant sleep disorder care in the Veterans Health Administration (VHA) Polytrauma/Traumatic Brain Injury System of Care (PSC). Second, to assess usability, a...

EuroMillions Breakthrough Mining — 1230 Sources, 7832 Leads Extracted — E8 Intelligence Research

Mined 1230 lottery+quantum breakthroughs. Extracted 7832 leads across 13 categories. 5985 high-value leads found. Categories: {"CORRIDOR": 623, "FORMULA": 483, "GEOMETRIC": 657, "FORWARD_ATTEMPT": 648, "QUANTUM": 859, "TIMING": 169, "CELESTIAL": 569, "GEMATRIA": 607, "CONSTANT":...

Co-Folding Confidence Dispersion Is a Coarse Binder Filter, Not an Affinity Ranker: Boltz-2 sigma-iptm Evaluated Against Potency Rank, Same-Chemotype Weak Binders, and Property-Matched Decoys on Matrix Metalloproteinase-1

The dispersion of co-folding confidence across an inference ensemble is widely used to triage protein-ligand predictions, but what it measures has not been fixed against experiment. This work evaluates Boltz-2 sigma-iptm, the standard deviation of iptm over 100 diffusion samples,...

Trinity Unity — A Meta-Thinking Framework for Humanity's Understanding of the Universe

This paper proposes a meta-thinking framework named "Trinity Unity," aimed at providing a self-consistent, open, and falsifiable foundational framework for humanity's understanding of the universe. The framework consists of three core levels: Ontology (Information-Energy-State Un...

Tipping the Scales Using Cryopreservation: Modelling the Genetic Value and Management Potential of Integrated Cryopreservation for Threatened Ex‐Situ Pupfish Populations

ABSTRACT Zoos and aquaria must retain genetic diversity for the species they house if the populations are to remain viable. The cryopreservation and storage of living animal cells is a potential strategy for minimising genetic diversity loss over time, when genetic diversity can...

Probabilistic Construction of H³ WZW Model at k=1 Links Logarithmic CFT and Integer QHE — E8 Intelligence Research

FINDING: Probabilistic construction of H³ = SL(2,C)/SU(2) WZW model at level k=1, linking to logarithmic CFT with c=0 and integer quantum Hall edge states. | MATH: WZW model on hyperbolic 3-space H³; target space SL(2,C)/SU(2) (non-compact); level k=1 corresponds to central charg...

Decoupling Electronic Activation and Pore Connectivity in Acidic Oxygen Reduction on Metal‐Free Biomass‐Derived Carbon Catalysts

Acidic oxygen reduction is often discussed as if catalytic activation and mass transport were inseparable. Here, biomass‐derived carbon was used to examine these contributions through oxidation, ammonia annealing, and KOH activation. The onset potential is associated primarily wi...

Qontext: A Quipu-Inspired Conversational Memory for Local Language Models

A conversational memory for language models that stores short, self-contained third-person facts ("knots") and returns only those a given prompt needs, inspired by the Inca quipu. On 800-turn conversations with human-written dialogue as filler, a 12B model answers 9.7/10 planted-...

Field Equations from a Common Foundation

This work derives the Einstein field equations and the equation structure of quantum field theory from a single discrete foundation — the {0,1}³ cube, direction counting, the tick as measurement information (τ = n·tP), and update consistency. Principle I (linearity): the energy l...

From Fold to Chemistry

Local publication candidate for From Fold to Chemistry, version 1.4.0. Integrates the independent Lean 4 whole-model PASS over 2,777 current claims. An Exact, Parameter-Free and Machine-Closed Complete-Field Reconstruction of Chemical Science from Smithian Fold Theory