Research works

The Universe Is A Program, Representations Issues (Version I)

The goal of this paper is to Compose new methods and processes. The Universe as a Program is a reprensentation to start composing all of existing and living entities (in the Universe). We argue important representations issues. Many new findings will be presented.

Multi-scale Evaluation of Rutting Resistance in Reclaimed Asphalt Pavement Mixtures through Linking Binder Rheology with the Hamburg Wheel-Tracking and the IDEAL Rutting Tests

This study proposed a multi-scale framework for evaluating rutting resistance in recycled asphalt mixtures by linking binder rheology with mixture-scale performance. One virgin mixture and seven mixtures containing 50% reclaimed asphalt pavement (RAP) were prepared with three rej...

Cholera endemicity as a systems failure: a STAMP-CAST investigation in Kakuma and Dadaab refugee complexes in Kenya

Abstract Background Cholera outbreaks continue to pose a significant public health threat in Kenya and other low-and middle-income countries, particularly in humanitarian settings where overcrowding, inadequate water and sanitation services, population mobility, and climate-relat...

Intraoral Scanners: Enhancing Dental Education

ABSTRACT Introduction This study evaluated how integrating intraoral scanners (IOS) into Digital Dentistry and Operative II courses at Tufts University School of Dental Medicine (TUSDM) influenced second‐year dental students' perceived understanding of ceramic inlay preparations...

Structural insights into a substrate translocation pathway revealed by the RND efflux pump complex MexJK from Pseudomonas aeruginosa

Resistance–nodulation–cell division (RND) efflux pumps are the major cause of multidrug resistance in Pseudomonas aeruginosa . The inner membrane protein MexK from P. aeruginosa is a narrow-spectrum RND transporter. It assembles with membrane fusion protein MexJ and outer membran...

Deep Mycobacterium marinum Infection of the Digit Presenting Without Cutaneous Lesions: A Case Report

Mycobacterium marinum is a slow-growing nontuberculous mycobacterium acquired through breaches of the skin during contact with fish or aquatic environments. It classically produces a cutaneous papulonodular lesion of the hand, but deeper involvement of tendon sheaths, joints, and...

OvercomingElectrochemiluminescence Immunoassay (ECLIA)Limitations: Conformation-Independent Quantitation of a TherapeuticAntibody by LC–MS/MS

Abstract Monoclonal antibody therapies have transformed cancer treatment by enabling targeted intervention even in advanced disease stages. However, reliable monitoring of circulating therapeutic antibody levels is critical to ensuring efficacy and patient safety. This study inve...

Global Mittag–Leffler synchronization of fractional-order Clifford-valued neural networks with mixed time-varying delays via adaptive quantized pinning control

Abstract The objective of this paper is to establish verifiable synchronization criteria for fractional-order Clifford-valued neural networks with mixed time-varying delays when the response system is controlled through finite-resolution communication channels. The model contains...

Anorectal manometry after rectal cancer surgery: physiological insights, clinical interpretation, and limitations

Abstract Anorectal manometry (ARM) provides objective physiological information on anal sphincter function, rectal or neorectal sensation, reservoir capacity, and anorectal reflexes after rectal cancer surgery. In rectal cancer surgery, ARM has been used to evaluate functional ch...

Enrollment is not coverage: integrity gates, their measured detection rates, and the limits of self-checking documentation

This is an experience report with n = 1, self-reported: the same author wrote the documents, the gates that check them, and this account of what the gates found, and no independent party re-ran anything. Every structural failure it describes was found by the apparatus catching it...

Computer Vision-Based Information Extraction from Electrical Assets: A Systematic Literature Review

Automated inspection of electrical equipment has become increasingly important as utilities seek to replace inefficient manual processes in infrastructure management. Electrical-equipment nameplates contain critical technical information, but automatically extracting this informa...

A Stabilizer Obstruction for Anonymous and Object-Neutral Classification Aggregation

We disprove a conjectured prime-divisor characterization for anonymous and object-neutral classification aggregation. A general stabilizer obstruction and explicit profile gadgets show that, for every m ≥ 5, ρ = m − 2, and n ≥ 2, no deterministic resolute anonymous and object-neu...

‘The real win is doing this for a living’: Routes, routines and rewards of music managers

Studies of the music industry have traditionally prioritized its creative dimensions, especially musicians’ activities. When ‘non-creative’ aspects of music creation are examined, they are typically approached through musicians’ own ‘non-creative’ activities. Despite the insisten...

Ropeginterferon alfa-2b in Polycythemia Vera: A systematic review and meta-analysis

Background: Ropeginterferon alfa-2b, a novel monopegylated interferon with improved pharmacokinetics, has emerged as a promising cytoreductive agent for managing polycythemia vera (PV). Despite increasing adoption, evidence synthesis of its efficacy and safety compared to standar...

Boundaries of Machine Interpretation

Boundaries of Machine Interpretation is a bilingual, versioned authorial statement set by Ivan Kotov. Version 0.2 consolidates six connected formulations: the future as a process; doubt versus numerical uncertainty; forgetting versus data loss; empathy versus optimization; subjec...

Failing to Maintain Contact With Probation: Discovering the Reasons Why

A common requirement for individuals on probation is to remain in contact with their probation officer (PO). Failure to do these actions may result in a violation that could lead to a revocation. Further, not knowing one’s whereabouts on probation could create public safety conce...

Toward Permanence Yet Unattainable: A Thermodynamic Interpretive Framework for the Evolution of Planetary Surface Systems

The second law of thermodynamics dictates that isolated systems undergo monotonic entropy increase, tending toward disorder and homogeneity. However, over 4 billion years of Earth's stratigraphic and paleontological records, planetary surface open systems have persistently exhibi...

Multiomics Insights Into AL Amyloidosis

ABSTRACT Light chain amyloidosis is a systemic or localized protein conformational disorder triggered by misfolded immunoglobulin light chains, leading to amyloid fibril deposition. The disease is characterized by multiorgan involvement and delayed diagnosis, contributing to poor...

Heavy‐Halide Coordination and Lattice‐Confined Molecular Alignment Enable Giant Birefringence in Hybrid Metal Halides

ABSTRACT High‐birefringence materials are essential for polarization optics, yet it remains difficult to translate anisotropic molecular building blocks into a strong directionally accumulated crystal‐scale optical anisotropy. Here, we establish a hybrid metal halide engineering...

Characterization of porcine heart for the development of taste-rich and bioactive hydrolyzates using sequential hydrolysis

Abstract The increasing production in global meat industry requires strategies to minimize the economic and environmental impact of slaughterhouse by-products. The main objective of this research was to characterize porcine heart as a raw material for developing functional and ta...