Research works

Antimicrobial effectiveness within a new paradigm of infrastructure

Antimicrobials form the backbone of modern medicine and represent a foundational pillar of economic productivity. Overuse and misuse have led to a rising trend of antimicrobial resistance (AMR), depleting the efficacy of existing antimicrobials, necessitating conservation through...

Evolution of water clarity across the Beijing-Tianjin-Hebei region over the past four decades (1984–2024): Driven by hydrological expansion and anthropogenic intervention

Given escalating water scarcity and rapid urbanization, characterizing the long-term evolution of surface water environments across the Beijing-Tianjin-Hebei (BTH) region is vital for coordinated regional development. Using Landsat imagery spanning 1984–2024, this study quantifie...

Drug-specific effects of anxiety on high-dose oxycodone: age as a modifier for oxycodone response

To investigate the association between preoperative anxiety and opioid tolerance in patients undergoing primary hip arthroplasty, focusing on heterogeneity across opioid types and the mechanisms underlying this association, this retrospective cohort study identified 1763 such pat...

Durability of wrist denervation for osteoarthritis: a multicentre outcome study

INTRODUCTION: Traditional surgical treatments for wrist osteoarthritis, such as arthrodesis or arthroplasty, are invasive and irreversibly compromise joint motion. Wrist denervation offers a less invasive alternative aimed at pain relief while preserving mobility. However, its du...

Research on the Impact Mechanism and Spatial Effects of the Digital Economy on Regional Economic Resilience in the Yellow River Basin of China

Against a backdrop of rising macroeconomic uncertainty, the digital economy has become a key driver of regional economic resilience. However, research on this relationship still requires further refinement for the Yellow River Basin, a special region characterized by ecological r...

Neuropeptide Alterations in Type 2 Diabetes Mellitus: A Meta‐Analysis of Circulating Spexin and Galanin Levels

ABSTRACT Background Spexin and galanin are neuropeptides involved in glucose homeostasis, insulin sensitivity, appetite, and energy metabolism. We conducted a systematic review and meta‐analysis to synthesise evidence on circulating spexin and galanin concentrations in patients w...

Seemingly conscious AI risks

AI systems are increasingly designed in ways that lead users to perceive them as conscious. This paper provides a unified framework connecting empirical hallmarks of consciousness attribution to a structured risk taxonomy of Seemingly Conscious AI (SCAI), AI systems that exhibit...

CNN-GRU-KAN: A Novel Multi-Branch Framework for Parkinson’s Disease Detection Based on Gait Classification

Parkinson’s disease (PD) diagnosis and severity assessment increasingly rely on gait analysis. To capture complex gait dynamics from limited sensor data, we propose a novel multi-branch framework integrating a one-dimensional convolutional neural network (1D-CNN), a bidirectional...

Revisiting the Indian Oedipus: The Phallus is (Also) Female

This paper revisits the psychoanalytic concept of the Oedipus complex through the lens of Indian psychoanalytic theory, Hindu goddess traditions, and clinical material drawn from work with Indian and diasporic patients. Challenging Eurocentric models that center paternal interdic...

Bottlebrush Polyolefin Sulfones as Triggerable and Degradable Pressure‐Sensitive Adhesives

ABSTRACT The molecular architecture (topology) of bottlebrush polymers, featuring densely grafted side chains along a polymeric backbone, leads to unique physical properties, enabling their use as functional materials including elastomers and pressure‐sensitive adhesives (PSAs)....

Integrated Quantum Dot Microsphere-Based MultiplexLateral Flow Immunoassay for On-Site Hazard Screening of Azole AntifungalResidues in Ecological Environment and Aquatic Products

Abstract As widely applied azole antifungal agents, climbazole (CBZ), clotrimazole (CLZ), and isavuconazole (ISKZ) can persist in environmental media and bioaccumulate in aquatic organisms, thus bringing hidden risks to the ecological environment and aquatic products. Herein, a c...

Multiple Myeloma Complicating Breast Cancer During Treatment: A Case Report

Research Background: Breast cancer is a malignant tumor that threatens women’s health. Among breast cancer patients, about 4.2% to 17% may suffer from multiple primary malignant neoplasms. Cases of patients suffering from both breast cancer and multiple myeloma are relatively rar...

Bankruptcy Prediction from 10-K Narratives: Evidence from Interpretable Text Scores and Accounting Baselines

This study examines whether context-validated acute distress disclosures in annual Form 10-K filings improve bankruptcy-risk ranking beyond accounting variables. The analysis links U.S. Securities and Exchange Commission filing data, Item 7 Management’s Discussion and Analysis te...

Sustainable Design Strategies for Human–Cat Shared Furniture in Compact Apartments: An Integrated SOR–Kano–FBS Approach

As urban housing becomes increasingly compact and companion animals become more deeply integrated into domestic life, human–cat cohabitation presents design challenges related to spatial efficiency, furniture wear, maintenance, and everyday coexistence. This study examines shared...

A Case of Drug-Induced Eosinophilic Pneumonia Caused by Nijutsuto Identified through Online Eligibility Verification

A 75-year-old woman presented to an orthopedic clinic at another hospital for periarthritis of the shoulder and was prescribed nijutsuto. On day 24 after initiation, she developed exertional dyspnea. On Day 26, she discontinued nijutsuto on her own because she perceived no improv...

Clinical Characteristics, outcomes, and mortality predictors of sepsis patients in an East African emergency department at Mogadishu, Somalia: an observational cohort study

Sepsis is a life-threatening syndrome associated with substantial morbidity and mortality, particularly in low- and middle-income countries (LMICs), where prospective emergency department data remain limited. In Somalia, evidence describing the clinical characteristics and outcom...

Bias in Cohort Studies: The Critical Importance of the “Why” and “When” of Treatment Decisions

When it comes to high-quality, rigorous research, children generally get the short end of the stick. Randomized controlled trials (RCTs)—the “gold standard” for clinical research1—are rare in this population.2 RCTs are expensive, time-consuming, and often fraught with ethical con...

“Grafting-From” Synthesis of Cellulose Acetate-graft-Poly(propylene carbonate) and Evaluation of Its Physical Properties

Poly(propylene carbonate) (PPC) is synthesized through the alternating copolymerization of propylene oxide (PO) and carbon dioxide (CO2) and has been widely studied as a sustainable polymer material. Although PPC is known for its biodegradability, biocompatibility, high optical t...

Efficacy of percutaneous transhepatic gallbladder drainage for acute cholecystitis during pregnancy: a retrospective cohort study

Contrary to the current guidelines, pregnant patients with moderate to severe acute cholecystitis (AC) often avoid surgery due to concerns of the potential maternal and fetal risks. Percutaneous transhepatic gallbladder drainage (PTGBD) can serve as an alternative to emergent cho...

Challenges and approaches to genetic variants of uncertain significance in clinical practice and research

Despite advances in sequencing technologies and variant interpretation frameworks, many variants identified in genetic testing, particularly missense variants, remain classified as variants of uncertain significance (VUS), posing ongoing challenges in diagnosis and clinical manag...