Research works

An Integrated Human-in-the-Loop Patent Search Workflow: An Exploratory Case Study Combining Keyword, Similarity, Semantic, and Citation-Based Retrieval

Patent retrieval is important for innovation management, R&D planning, and intellectual property strategy, yet conventional searches are hindered by terminology variability, synonymy, broad patent scopes, and classification limitations. This study presents an integrated, iterativ...

An ECT probe featuring array TMR sensors and a coaxial excitation for the inspection of defects beneath rivets

Detecting defects beneath rivets in multilayer metallic structures remains a challenge in eddy current testing (ECT). This paper presents a rotational eddy current probe that integrates a coaxial excitation coil with an array of high-sensitivity tunnelling magnetoresistance (TMR)...

Fluorinated Microporous Organic Network-Based Cooling-Assisted SPME for Ultra-Trace Determination of Fluorinated Liquid Crystal Monomers

Abstract Fluorinated liquid crystal monomers (FLCMs), widely used in electronic displays, have emerged as persistent and bioaccumulative contaminants, yet their ultra-trace determination in complex matrices remains challenging. Herein, a cooling-assisted solid-phase microextracti...

Differences in Dust Emission and Near‐Surface Transport Patterns Among Three Surface Substrate Types

ABSTRACT Soil wind erosion is a major driver of atmospheric dust emissions and land degradation. Many studies have examined dust release from different substrates, but differences in methods and units still limit quantitative understanding of how surface conditions and wind joint...

All‐Sputtered Oxide n‐p Heterojunction Anti‐Ambipolar Transistors for Semantic Segmentation Networks

ABSTRACT Neuromorphic vision provides an efficient route for extracting meaningful information from visual inputs and supporting intelligent perception in dynamic environments. However, visual scenes acquired under excessive or insufficient illumination often contain distorted co...

THE RESOLUTION OF THE SCHWARZSCHILD CRASH: DETHRONING MECHANICAL SINGULARITIES THROUGH THE LENS OF SABTO WIBOWO'S HIGH-ORDER QUANTUM CHRONODYNAMICS

This theoretical manuscript delivers a terminal mathematical resolution to the century-old coordinate singularity crisis that paralyzes Albert Einstein’s General Relativity at the core of a black hole. Standard mechanical-material physics dictates that as the gravitational radius...

Development of a Potent and Isoform-Selective HDAC11 Inhibitor with Anti-Tumor Efficacy against Non-Small Cell Lung Cancer

Abstract Targeting histone deacetylase 11 (HDAC11) represents a promising therapeutic strategy, yet developing selective inhibitors for solid tumors remains a formidable challenge. Herein, we describe the rational lead optimization of a novel series of indole-based hydroxamic aci...

Physical Parameters Influencing the Rate of Subretinal Injection: A Microfluidic Analysis

Purpose: Subretinal injection during vitrectomy has become an important technique owing to the growing number of cell and gene therapy trials for retinal disease. Reducing the injection rate can mitigate trauma or shear forces on the retinal pigment epithelium, yet many surgeons...

Gut microbiota and type 2 diabetes: implications for personalized nutrition and emerging therapeutic strategies

Type 2 diabetes mellitus (T2DM) is a complex metabolic disorder characterized by insulin resistance, impaired glucose regulation, and chronic low-grade inflammation. Over the past decade, the gut microbiota (GM) has emerged as an important determinant of metabolic health, with in...

Impaired Flow and Physiology in Coronaries With Anomalous Origin From the Opposite Sinus of Valsalva

BACKGROUND: Anomalous Aortic Origin of a Coronary Artery (AAOCA) high-risk anatomical features (intramural segment, acute take-off angle, slit-like ostium) cause coronary stenosis leading to myocardial infarction. How these features alter coronary physiology remains unclear. AIMS...

Control Volume Free Element Method for Simulating Thermal Runaway of Lithium-Ion Battery

The safety of lithium-ion batteries is a critical concern, and this paper introduces a novel simulation approach for thermal runaway using the control volume free element method (CVFrEM). This method uniquely integrates the geometric adaptability of mesh-free techniques with the...

Associations of long-term Tai Chi practice with vascular health in middle-aged and older adults: potential indirect roles of inflammation and oxidative stress - a cross-sectional study

Tai Chi is a widely practiced mind-body exercise, but its associations with vascular health and the potential involvement of inflammation and oxidative stress remain unclear. We hypothesized that, compared with irregular exercise, long-term Tai Chi practice would be associated wi...

Genome-Wide Identification and Stress-Responsive Expression Analysis of the PR-1 Gene Family in Paulownia fortunei

Pathogenesis-related protein 1 (PR-1) genes are involved in plant defense responses and abiotic stress responses. In this study, a total of 14 PfPR-1 family members were identified from the genome of Paulownia fortunei, and their physicochemical properties, phylogenetic relations...

Pu-Doping-Induced Weberite-like Local Motifs and Enhanced Immobilization in Gd2Zr2O7 Pyrochlore: A DFT + U Study

Abstract This study employs density functional theory with the Hubbard U correction (DFT + U) method to investigate how Pu incorporation into distinct sites (Gd or Zr) in Gd2Zr2O7 governs locally weberite-like disorder and subsequently influences Pu immobilization behavior. We re...

Accessible Tourism After the European Accessibility Act: Signalling in Hotels and Private Accommodation Across Four European Union Countries

The European Accessibility Act (Directive (EU) 2019/882) has applied, since June 2025, extending binding accessibility requirements to the e-commerce infrastructure through which tourism is sold. Whether that obligation is visible in tourism markets remains largely untested, and...

Identification of a Novel Druggable Pocket in the HIV-1 gp120 C5 Domain at the Conformational Relay Junction

HIV-1 entry requires a conformational relay that transmits the receptor-engagement signal to membrane fusion activation, yet no approved drug targets this transmission step. Here I report a novel druggable pocket in the gp120 C5 domain (Arg465-Arg472, sequence RPGGGDMR) at this r...

Population-Based Discrimination of Classical and Few-Photon Microwave Fields with a Flux-Tunable Transmon Qudit

Interactions between few-photon microwave fields and superconducting artificial atoms provide a method to study photon statistics and manipulate quantum states for photonic quantum information processing. Superconducting transmons couple to microwave fields through an anharmonic...

Feasibility and safety of early bedside personalized rehabilitation in acute decompensated heart failure: a pilot randomized trial

The initiation of individualized bedside rehabilitation during the acute phase of acute decompensated heart failure (ADHF), particularly among elderly patients, remains insufficiently understood. Although early rehabilitation may improve mobility, alleviate congestion, and enhanc...

AR: An Artificial Intelligence‐Driven Fluorescent Reporter System for Gene Editing Evaluation

ABSTRACT Accurate and scalable evaluation of gene‐editing efficiency is crucial for the development of novel editing tools. However, conventional methods are laborious, costly, and low‐throughput. Here, we developed an artificial intelligence (AI)‐driven fluorescent reporter (AR)...

A Cybernetic Framework for the Central Governor: Reinterpreting Subjective Exhaustion as Predictive Safety Margins in High-Capacity Analytical Athletes

Classical exercise physiology often interprets physical fatigue as an absolute peripheral failure caused by metabolic byproductaccumulation. The Central Governor Model (CGM) revised this paradigm by proposing that the central nervous system (CNS)regulates performance to prevent c...