Research works

A quality improvement initiative to optimize diagnostic and antimicrobial stewardship of ventilator-associated tracheitis in the pediatric intensive care unit

OBJECTIVE: To reduce frequency of endotracheal aspirate culture (EAC) collection and decrease antibiotic days of therapy (DOT) for ventilator-associated tracheitis (VAT). DESIGN: Quality improvement intervention. SETTING: Tertiary-care pediatric intensive care unit (PICU). PATIEN...

Universalism and its Others: Transcultural psychiatry and Swedish exceptionalism after 1945

This article traces the historical development of transcultural psychiatry in Sweden from the post-Second World War period to the early 21st century. It argues that the field emerged at the intersection of welfare universalism, humanitarian internationalism, and clinical encounte...

Easily Accessible and Highly Active Heterogeneous Nickel Catalyst Supported by Covalent Organic Framework for In Situ Ethylene Polymerization

ABSTRACT The heterogenization of homogeneous transition‐metal catalysts is a well‐established strategy for enabling oriented synthesis and precise morphological control of high‐molecular‐weight polyolefins. To date, however, the development of covalent organic framework (COF)‐sup...

Qalb: Largest State-of-the-Art Urdu Large Language Model for 230M Speakers with Systematic Continued Pre-Training

Despite remarkable progress in large language models, Urdua language spoken by over 230 million people remains critically underrepresented in modern NLP systems. Existing multilingual models demonstrate poor performance on Urdu-specific tasks, struggling with the language’s compl...

Quantifying and Counteracting the Impact of Erroneous and/or Incomplete Information via High-Order Predictive Modeling: Methodology and Illustrative Applications to Nuclear Reactor Models

This work highlights the major benefits of applying the “Fourth-Order Best-Estimate Predicted Results with Reduced Uncertainties Predictive Modeling” (4th-BERRU-PM) methodology to quantify and remedy the impact of possibly faulty computational or experimental information. After d...

Time-Resolved Fluorescence of a Two-Level System Using Time-Dependent Variational Method

The time-resolved fluorescence spectrum of a driven two-level system is investigated using a time-dependent variational method. We first establish the transient build-up of the Mollow triplet via the Lindblad master equation under the rotating-wave approximation, providing a comp...

Using earth observation for national high resolution dynamic material stock modelling through time; assessing sand consumption in Malaysia from 1989 to 2020

Abstract Understanding the spatio-temporal dynamics of volumes of construction materials is becoming crucial for environmental sustainability and achieving long-term development goals. Whilst direct data collection is always the preferable option it is not always practical. This...

UG.NUG

A short version, The voice of the Universe, is available on this platform: https://doi.org/10.5281/zenodo.21486180 . This presentation challenges the Big Bang paradigm (BBP). According to our observations, the history of the universe did not unfold as it describes. To put it simp...

Preparing Future Social Educators for Artificial Intelligence: Perceived Use, Self-Reported Learning Competencies, and Professional Knowledge Requirements

Artificial intelligence (AI) is rapidly transforming higher education, requiring universities to prepare graduates who can use these technologies critically, ethically, and responsibly. However, socially oriented professions remain comparatively underexplored. This study examined...

Exploring Immersive Virtual Reality as an Approach to Improve School Participation–Related Constructs in Children With ADHD

ABSTRACT Background School participation is frequency and involvement from person–environment transactions, not diagnosis, per the International Classification of Functioning, Disability and Health (ICF) and the family of participation‐related constructs (fPRC). In this framework...

The effects of workation experience on destination loyalty: examining the roles of well-being and work productivity

Purpose This study examines how workation experience translates into destination loyalty by comparing the roles of affective and functional outcomes, namely well-being and work productivity, within tourism contexts. Design/methodology/approach A sequential mixed-methods design wa...

Dietary Yeast Hydrolysate Alters Serum Metabolic Profiles and Selected Fecal Bacterial Taxa in Lactating Dezhou Jennies

Yeast hydrolysate (YH) is a yeast-derived functional feed ingredient containing bioactive peptides, amino acids, nucleotides, β-glucans, and mannan oligosaccharides, which may exert prebiotic-like effects by regulating nutrient metabolism, host health, and intestinal microbial ho...

Occupational access to firearms and firearm-related suicide among US workers.

Objective: To examine the association between occupational access to firearms and firearm-related suicide, adjusting for worker demographics and rural residence. Methods: We conducted a mortality case-control study using National Violent Death Reporting System data (2013-2023). O...

Isoform-Specific Modulation of PI3K/Akt1 Signaling by Orai Channels in Estrogen Receptor-Positive Breast Cancer

The phosphoinositide 3-kinase (PI3K)/Akt signaling pathway is a fundamental intracellular axis that integrates extracellular stimuli to orchestrate essential cellular processes. The activation of Akt1 represents a key determinant of aggressiveness in estrogen receptor positive (E...

“Every Tool Is a Weapon If You Hold It Right”: Curating Feminist and Queer Listening Experiences in the Work of Ani DiFranco

Widely associated with third- and fourth-wave feminism, Ani DiFranco’s artistic practice creates and curates queer and feminist musical experiences through the tools of songwriting and spoken-word poetry. Since the release of her eponymous debut album in 1990, DiFranco has carved...

Communication crossroads

ABSTRACT Nurses have up to four times more patient contact than physicians, positioning them as central drivers of communication in health care. Effective communication directly influences patient outcomes, teamwork, staff engagement, and the overall care experience. Today's nurs...

The Carlo Temporal Engine V2

The Carlo Temporal Engine: A Reconstruction of Time A systems-theory framework that reconstructs time not as a fundamental dimension, but as an emergent behaviour of recursive systems. Across seven "unfolding passes," the paper develops time as a stability artefact generated to p...

Completion of the 5′ end of the porcine teschovirus genome reveals a functional S-segment and enables reverse genetics

Porcine teschoviruses (PTVs) are swine-specific picornaviruses associated with neurological and systemic disease, ranging from severe paralytic Teschen disease to milder forms of porcine encephalomyelitis, known as Talfan disease. Despite their global distribution and veterinary...

Fluorine-InducedElimination Drives Mechanism-BasedInactivation of Isocitrate Lyase

Abstract Fluorinated succinate analogues were evaluated as mechanistic probes of Mycobacterium tuberculosis isocitrate lyase (MtICL). However, 2,2-difluorosuccinate (1; Ki = 6.1 mM) and 2,2,3-trifluorosuccinate (2; Ki = 23.5 μM) act as reversible noncompetitive inhibitors and mes...

Curcumin Nanoemulsion: Characterization and Effect on Cataracts in an In Vivo Animal Model and Ex Vivo Human Model

Cataracts are the leading cause of reversible blindness worldwide; this condition results from the aggregation of lens proteins. Currently, surgery remains the only treatment; however, there is growing interest in non-surgical approaches, including the use of bioactive compounds...