Research works

Hyaluronic Acid Hydrogel Incorporating Dexpanthenol-Engineered Extracellular Vesicles for Accelerated Wound Closure and Mitigated Secondary Infection Risk

Background: Loss of epithelial integrity leaves the wound bed open to opportunistic bacterial colonization, and the risk of secondary infection persists for as long as the defect remains unclosed. Wound dressings must therefore provide an immediate external barrier while accelera...

A general kinematic framework for mobile-linkage robotic systems (MLRS)

Abstract Conventional mechanisms (linkages) are typically characterized by the presence of a frame that remains fixed with respect to an inertial reference system. In contrast, mobile robotic systems, including articulated robots, consist of assemblies of rigid bodies that are fr...

Bibliometric Analysis of Artificial Intelligence Use in Small Animal Thoracic Radiography

ABSTRACT Background Artificial intelligence (AI) is increasingly used in veterinary diagnostic imaging, particularly in thoracic radiology, to support image interpretation. Objective The aim of this study was to evaluate research trends in AI applications for small animal thoraci...

A Survey of Causal Learning in Graph-Based Recommender Systems

Graph-based recommender systems (GBRs) have achieved remarkable success by leveraging Graph Neural Networks (GNNs) to model complex user-item interactions and structural relationships. However, they still face major challenges in real-world environments, including out-of-distribu...

Influence of Unit Irregularity on the Shear Behavior of Rubble Stone Masonry Walls

The increasing availability of high-resolution geometric data has enabled microscale simulations of rubble stone masonry with varying levels of geometric fidelity; however, the influence of geometric simplification on predicted mechanical behavior remains unclear. This study inve...

Synthesizing Colloidal Bimetallic Nanoparticles in Water Using a Dual‐Ligand Strategy

ABSTRACT Controlled aqueous synthesis of bimetallic nanoparticles below 5 nm remains challenging due to reduction potential mismatches between noble and base metals, which often causes uncontrolled aggregation. Here, we propose a dual‐ligand strategy to assist the commonly used s...

From herbal cuisine to lasting memory: dining experiences in traditional Chinese medicine diet restaurants

Purpose Drawing on stimulus–organism–response theory, this study developed a memorable dining experience model linking four restaurant attributes (food, service staff food recommendations, service quality and atmospherics) to memorable dining experiences, revisit intentions, and...

Effects of long-term storage on proteome and quality characteristics of soybean

As an important source of plant protein and oil, soybean's protein quality degradation during storage can significantly affect processing characteristics and product quality. However, research on the molecular changes of soy protein under long-term storage is still limited. This...

An efficient ranking deep neural network algorithm for the prediction of Ca2+ binding sites of the protein

The Ca 2+ binding sites of proteins are critical for their function, particularly in processes such as signal transduction, enzyme regulation, and structural stability. In this study, the calcium-binding sites of Nt Eh CaBP1 (Entamoeba histolytica calcium-binding protein). This p...

Aortic Arch Surgery: Progress, Perspectives and Future Challenges

The aortic arch remains one of the most challenging areas in cardiac surgery, requiring a unique combination of surgical accuracy, physiological insight, multidisciplinary collaboration, and intraoperative decision-making [...]

Lattice Gauge Theory: Non-Perturbative QCD, Confinement, and Heavy-Quark Mass Extraction — E8 Intelligence Research

FINDING: Lattice gauge theory discretizes continuous gauge fields onto a spacetime lattice for non-perturbative QCD computation, with confinement emerging from Wilson loop area-law behavior. | MATH: Wilson action: \( S = \beta \sum_{\text{plaquettes}} \left(1 - \frac{1}{N} \text{...

DOPAL links dopamine dysregulation to neurodegeneration: a translational systematic review and meta-analysis

3,4-Dihydroxyphenylacetaldehyde (DOPAL) is the most reactive dopamine (DA)-derived aldehyde and has been implicated in selective dopaminergic neurodegeneration in α-synucleinopathies, including Parkinson’s disease (PD) and multiple system atrophy (MSA). Here, we present the first...

Comparative evaluation of Saccharomyces, Bacillus, and Lactobacillus as antibiotic alternatives on growth performance, redox balance, and gut microbiota in broilers

Abstract This study evaluated the efficacy of Saccharomyces cerevisiae (SC), Bacillus subtilis (B), Lactobacillus casei (LB), and their combination (Mix) as natural alternatives to antibiotics in broiler nutrition. Liquid cultures were prepared to a density of 10⁸ CFU/mL and exam...

Assessing ecosystem sustainability and green finance-based ecotourism opportunities in Akhar-Bakhar National Park

New ways of planning and managing protected areas are becoming more important, with an integrated approach of ecosystem management, visitor management, and sustainable financing. This study aims to evaluate ecosystem sustainability and ecotourism potential in green finance in the...

Premarital Preventive Examinations and Access to Genetic Counselling in the South-Central Region of Bulgaria: Implications for Preconception and Child Health

Background: Premarital medical certification is required before civil marriage in Bulgaria, but little is known about how newly married couples perceive this process within the broader framework of preconception care and genetic counselling. This study examined couples’ perceptio...

Conflict of Interest Policy

This document contains the Conflict of Interest Policy for the Institute of Replication.

Effects of Dietary Alpinia officinarum Extract on Performance, Immunity, Microbiota, and Aeromonas hydrophila Resistance in Red Claw Crayfish

Plant extracts contain multiple bioactive compounds and have been extensively investigated as alternatives to antibiotic-based feed additives in aquaculture. The present study was designed to evaluate the effects of dietary supplementation with galangal (Alpinia officinarum) extr...

Accuracy of Rome IV questionnaire: a population-based study on diagnostic definitions and clinical validity

Rome IV questionnaire is widely used for diagnosing disorders of gut-brain interaction (DGBIs), but was developed in Western populations and may not generalize to other regions. This study aimed to validate the Persian version of this questionnaire and develop population-adapted...

Can Corporate Social Responsibility and Good Corporate Governance Drive Firm Value? Evidence from Indonesian Mining Companies

ABSTRACT : Corporate social responsibility (CSR) and corporate governance have become increasingly important determinants of firm value, particularly in environmentally sensitive industries such as mining. However, empirical evidence on their effectiveness in enhancing firm value...

Establishment of a classification model for different grades of ribbed smoked sheets using near infrared spectroscopy and convolutional neural networks

Natural rubber is a vital industrial raw material and strategic resource. Ribbed smoked sheet is a traditional solid natural rubber that accounts for a significant proportion of the manufacturing of high-performance tyres. Presently, the grading of ribbed smoked sheet is primaril...