Research works

Integrating Drug Physicochemistry and Hfq-Dependent Regulation of Ciprofloxacin Accumulation in Escherichia coli

Ciprofloxacin (CIP), an amphoteric fluoroquinolone, undergoes pH-dependent changes in protonation state that influence membrane permeability and intracellular accumulation. Here, we investigated how drug physicochemistry and bacterial regulatory pathways jointly determine CIP acc...

A Risk‐Based Prioritization Model for Advanced Colorectal Neoplasia in Thailand: Strengths and Open Questions

Data sharing is not applicable to this article as no datasets were generated or analyzed during the current study.

Lysine-Based Amphiphiles with Pyrrole, Furan and Thiophene Linkers

The development of efficient cationic amphiphiles remains an important area in the design of nonviral systems for nucleic acid delivery. In this study, we report the synthesis of three lysine-containing lipid-like amphiphiles incorporating pyrrole, furan, and thiophene as five-me...

Thermo-exergetic optimization and local temperature field behavior in multi-tray solar drying systems with double-pass absorbers

Solar drying technology represents a sustainable solution for post-harvest food preservation in tropical regions; however, uneven internal airflow and poor thermal distribution across multi-tray chambers often cause inconsistent product quality and substantial thermodynamic losse...

Entropy-Guided BIST Instruction Set Compression for Auto-CP Embedded Flash Testing

Embedded Flash chip probing (CP) testing in an automotive Microcontroller Unit (MCU) involves long test flows and numerous test items. Conventional BIST-based testing relies on step-by-step Automated Test Equipment (ATE) instruction configuration, status polling, and result reado...

Histopathological and immunohistochemical analyses do not indicate timing of prophylactic hysterectomy: a retrospective analysis of endometrial biopsies in Lynch syndrome carriers

Abstract Women with Lynch syndrome are at increased risk of endometrial cancer. Gynecological surveillance is advised, but also prophylactic hysterectomy is an option. This study aimed to gain more insight in tumorigenesis in Lynch carriers to be able to personalize prophylactic...

Encoding Choice Is Associated with Large Differences in Variational Quantum Classifier Performance on Cancer Data Under a Fixed Training Budget

Variational quantum classifiers (VQCs) are often reported to perform poorly on biomedical tabular data, but such conclusions depend on the encoding circuit, the training budget, and the comparison protocol. Methods. We compared 4-qubit VQCs, a quantum-kernel SVM (QSVM), a majorit...

Hydrogel and Organogel-Based Flexible Wearable Sensors: Synthesis, Sensing Mechanisms, Performance Optimization, and Applications

Hydrogel-based flexible sensors have emerged as a promising platform at the intersection of materials science, flexible electronics, and biomedical engineering, owing to their tissue-like mechanical compliance, tunable ionic conductivity, and versatile chemical functionalizabilit...

EuroMillions Breakthrough Mining — 10356 Sources, 100959 Leads Extracted — E8 Intelligence Research

Mined 10356 lottery+quantum breakthroughs. Extracted 100959 leads across 13 categories. 97290 high-value leads found. Categories: {"CORRIDOR": 8825, "FORMULA": 8578, "GEOMETRIC": 1699, "FORWARD_ATTEMPT": 9270, "QUANTUM": 9524, "TIMING": 646, "CELESTIAL": 8644, "GEMATRIA": 9055, "...

Gendered guanxi and rural tourism entrepreneurship

This study develops a theory of gendered guanxi to explain how rural women entrepreneurs navigate and transform tourism development in China. Drawing on qualitative research in Zhuyi Village, a state-supported Model Village in China, we trace how women strategically do and redo g...

Six‐DoF Strawberry Harvesting Pose Selection and Adaptive Obstacle Clearing in Occluded Environments

In complex, unstructured orchard environments, accurate end‐effector pose selection is essential for low‐damage strawberry harvesting. This study proposes an occlusion‐aware 6‐DoF harvesting pose‐selection strategy with adaptive obstacle clearing for a fixed‐stroke two‐finger end...

Augmented enhancement of valproate efficacy by taurine and pyridoxal phosphate via gabaergic metabolic support in epilepsy

A major clinical dilemma in epilepsy treatment lies in the difficulty of balancing efficacy and safety. First-line antiepileptic drugs such as valproic acid (VPA) exhibit dose-dependent side effects. Enhancing γ-aminobutyric acid (GABA)ergic inhibition is a core therapeutic strat...

Closed-Form Fibonacci via Path-Sums on Fibonacci Trees — E8 Intelligence Research

FINDING: Fibonacci numbers admit a closed-form via combinatorial path-sums on Fibonacci trees, independent of prior terms. | MATH: Let \(F_n\) be the \(n\)-th Fibonacci number. The Fibonacci tree \(T_n\) has root value \(F_n\), left child \(T_{n-1}\), right child \(T_{n-2}\). The...

From Sensegiving to Sensemaking: TikTok Discourse Surrounding the House Settlement

In June 2025, the House v. National Collegiate Athletic Association (NCAA) settlement was reached, transforming college athletics and athletes’ compensatory rights and opportunities. Utilizing the theoretical coupling of sensegiving and sensemaking, this study explores how the ca...

Thermal Phase Behavior of PNIPAM-Based Hydrogels: Different Scenarios and Implications in Injectable Hydrogel Design

Poly(N-isopropylacrylamide) (PNIPAM)-based hydrogels are “smart” materials of great interest and demand, primarily in a variety of biomedical applications, due to their LCST close to physiological temperature. The basic biomedical applications of PNIPAM-based injectable hydrogels...

Estimation-Robust Minimum-Variance Portfolio Allocation Under Factor-Loading Uncertainty

We study sequential minimum-variance allocation when estimated market-factor loadings are uncertain. At each date, a horizon-one convex problem is solved using an ellipsoidal confidence region for the jointly estimated loading vector. The full loading covariance includes cross-as...

Cryptanalysis and Improvement of an Image Cryptosystem via Chaotic Synchronization and Artificial Neural Networks in Modified OTP Scheme

Chaos-based image ciphers may exhibit favorable statistical metrics while retaining a recoverable algebraic structure. We analyze the modified one-time-pad image cryptosystem of Stoycheva et al., which combines static, Chua-system-derived, and neural masks with channel-wise shuff...

An adaptively weighted targetless rotation axis calibration method based on angle prior

In rotary-stage structured-light 3D measurement systems, the calibration accuracy of the rotation axis determines the registration quality of multi-view point clouds. Among existing calibration methods, traditional target-based approaches are susceptible to the defocusing interfe...

Frost risk, phenology and adaptation in cold-climate viticultural systems

CONTEXT Late spring frost remains a major climatic constraint in cold- and cool-climate viticulture, where grapevine development is strongly shaped by seasonal temperature variability. Although climatic warming is often expected to reduce frost hazard through declining frost freq...

Wald transformation-based confidence interval for a coefficient of variation of Gamma distribution with applications to PM 2.5 dispersion measurement

Accurate estimation of the coefficient of variation (CV) is essential for assessing the variability of environmental pollutants such as fine particulate matter (PM2.5). This study proposes a Wald transformation-based (Wald-TB) confidence interval for the CV of Gamma-distributed d...