Research works

Non-local physics-informed neural networks for forward and inverse solutions of granular flows

Abstract Dense granular flows exhibit nonlocal effects due to stress transmission in microplastic events, especially in quasi-static or slowly sheared regions. Hence, traditional local rheological models fail to capture spatial cooperativity effects that are prominent in many gra...

Multiple introductions of highly pathogenic avian influenza viruses into the High Arctic: Svalbard and Jan Mayen, 2022–2025

Abstract Between 2022 and 2025, highly pathogenic avian influenza viruses (HPAIVs) of clade 2.3.4.4b, including four distinct H5 Eurasian (EA) genotypes, were detected in wild birds and mammals in the Svalbard Archipelago and on the island of Jan Mayen. We describe their epidemio...

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Private information leakage from polygenic risk scores

Abstract Polygenic Risk Scores (PRSs) estimate the likelihood of individuals to develop complex diseases based on their genetic variations. While their use in clinical practice and direct-to-consumer genetic testing is growing, the privacy implications of publicly sharing PRS val...

Genome-Wide Association Study of Corneal Dystrophy Uncovers Novel Risk Loci and Enables Improved Polygenic Prediction of Fuchs Endothelial Corneal Dystrophy

Abstract Objective To identify risk loci for Fuchs endothelial corneal dystrophy (FECD) and improve a genetic risk prediction model. Design Genome–wide association study (GWAS), polygenic risk score (PRS) construction, and TCF4 CTG18.1 short tandem repeat (STR) length inference....

Limits on marine carbon dioxide removal potential set by coastal air-sea gas exchange rates

<title>Abstract</title> Marine carbon dioxide removal (mCDR) has attracted significant interest as a strategy to mitigate rising atmospheric carbon dioxide (CO2) from fossil fuel burning in order to combat climate change, where a key variable is the gas transfer velocity (k), con...

Forecasting commencing enrolments under data sparsity: a zero-shot time series foundation models framework for higher education planning

Effective resource allocation in higher education depends on reliable enrolment forecasts, yet institutional planners frequently face data series disrupted by structural shifts. This paper investigates whether zero-shot Time Series Foundation Models (TSFMs) can provide rigorous d...

Influence of spatial connectivity on the spread of Mpox in Maï-Ndombe province, Democratic Republic of the Congo, 2025

<title>Abstract</title> <bold>Background</bold> The spread of Mpox in the DRC is strongly influenced by human mobility in a context of environmental constraints and inequalities in accessibility. The province of Maï-Ndombe, with its fragmented transport network and dependence on...

Short mode-locked pulses from planarized Y-coupled THz lasers

Short THz pulses are highly attractive both for fundamental research and practical applications in this underdeveloped region of the electromagnetic spectrum. Typically, THz pulses are generated using nonlinear optical methods, starting from a high-power visible or near-IR mode-l...

Inclusion of MyAMI-derived Mg ∕ Ca corrections to the marine carbonate system in the cGENIE.cookie Earth system model (v.0.91)

Abstract. The concentrations of the major cations (esp., Ca2+, Mg2+) in Earth's oceans have undergone large-scale fluctuations in the geological past. This is important because the key geochemical properties of the marine environment that underpin the global carbon cycle – the aq...

The new first listener: Daydreaming styles and self‐compassion predict adolescent disclosure to AI , differently in ADHD

AI chatbots are rapidly becoming a common place where adolescents first disclose personal experiences, because the interaction is private, always available, and often feels lower-stakes than telling another person. Recent U.S. evidence suggests that about one in eight adolescents...

Selective Intrinsically Photosensitive Retinal Ganglion Cells Ablation Regulates Myopia Development Through the Choroid/MAPK Pathway

Purpose This study investigates the role of selective ablation of intrinsically photosensitive retinal ganglion cells (ipRGCs) in regulating axial length (AL) and scleral remodeling during myopia progression.Methods Three-week-old pigmented guinea pigs were randomly assigned to f...

MERTK inhibition cooperates with immunomodulatory cyclophosphamide to induce CXCL9⁺ monocyte-macrophage programming and durable antitumor immunity in triple negative breast cancer

ABSTRACT Triple-negative breast cancer (TNBC) has high rates of recurrence despite chemotherapy and immune checkpoint blockade (ICB). Tumor-associated macrophages (TAMs) can either suppress or support anti-tumor immunity, but the mechanisms governing these states and therapeutic...

Learning Sequences and Events in Individual, Pair and Group Data-Driven Learning

Abstract Previous research has shown that the learning process in data-driven learning (DDL) is cyclical, iterative, and non-linear, even when tasks are designed around seemingly linear pedagogical frameworks such as Illustration–Interaction–Intervention–Induction (Carter, Ronald...

Forecast-based attribution of the role of stratospheric variability in weather extremes

Abstract. Variability of the stratospheric polar vortex, particularly its dramatic breakdown during sudden stratospheric warming (SSW) events, has been linked to a number of surface weather extremes. However, attributing the role of stratospheric variability in a specific observe...

Neonatal diethylstilbestrol exposure disrupts uterine epithelial apical–basal polarity and partial EMT state

Abstract The developing female reproductive tract is highly sensitive to external hormonal stimulation, which can result in infertility and gynecologic diseases. To determine the underlying mechanisms, we used a mouse model to test the immediate, cell type-specific effects of neo...

Comparative Analysis of Leader Election Algorithms In Distributed Systems

Author-deposited reprint of the published article: Piotrovskyi, Y. (2026). Comparative Analysis of Leader Election Algorithms In Distributed Systems. International Journal of Computer (IJC), 57(1), 11–26. Original online publication date: February 1, 2026. Version of record: http...

On Global Weak Solutions for the Magnetic Two-Component Hunter–Saxton System

Abstract We study the magnetic two-component Hunter–Saxton system (M2HS), which was recently derived in [19] as a magnetic geodesic equation on an infinite-dimensional configuration space. While the geometric framework and the global weak flow were outlined there, the present pap...

Integrated omics analysis provides preliminary insights into the regulatory network controlling ethephon-promoted calyx abscission in Korla Xiangli (Pyrus × sinkiangensis Yü)

<title>Abstract</title> Background Calyx abscission is a key horticultural trait affecting fruit quality in Korla Xiangli <italic>(Pyrus</italic> × <italic>sinkiangensis</italic> Yü <italic>).</italic> Exogenous ethephon treatment has been shown to significantly promote calyx abs...

Incorporating data drift to perform survival analysis on credit risk

Survival analysis has become a standard approach for modelling time to default by time-varying covariates in credit risk. Unlike most existing methods that implicitly assume a stationary data-generating process, in practise, mortgage portfolios are exposed to various forms of dat...