Research works

Integration of principal component analysis and supervised classification for mineral alteration mapping using satellite imagery, Kafta Humera, Ethiopia

Remote sensing is an important technique for lithological mapping and hydrothermal alteration detection; yet, achieving high classification accuracy remains difficult in complex geological environments. This study addresses the difficulty of delineating lithological units and alt...

Geometric Dynamics Unified Theory (GDUT)

Current physics faces several fundamental unresolved problems: the lack of direct observational evidence for dark matter; a discrepancy of approximately 120 orders of magnitude between predicted and observed values for dark energy; unresolved tensions in the Hubble parameter; and...

Entropy aware EnKF framework for reliable power quality prediction in smart grids

In this paper a novel predictive technique is proposed for power quality (PQ) event classification in smart grid. Here Ensemble Kalman filter (EnKF) based approach and Entropy based trust modelling are utilized to design hybrid learning model that can classify PQ events during no...

Twin reversed arterial perfusion (TRAP) sequence in a low – resource setting: a case report from South Sudan

Twin reversed arterial perfusion (TRAP) sequence, also known as acardiac twinning, is a rare complication unique to monochorionic twin pregnancies in which a structurally normal “pump” twin supplies circulation to a severely malformed, non-viable “acardiac” twin through abnormal...

Theory of Functional Agency: A System Dynamics Model Based on Boundary Maintenance, Internal-Origin Identification & Connection, and Irreversible State Change

[Abstract]This paper redefines the concept of "Agency"—which has long been conflated with psychological attributes such as "consciousness" or "intention," or biological structures—from a functional perspective, formulating an axiomatic system of "Functional Agency" as a universal...

Effects of Tabata training on physical fitness and mental health-related outcomes in children and adolescents: a systematic review and multilevel meta-analysis

Tabata training is a time-efficient form of high-intensity interval training, typically characterized by repeated 20-s bouts of high-intensity exercise interspersed with 10-s recovery periods. Although HIIT has been studied in children and adolescents, the specific effects of Tab...

Hostile microenvironment-driven oxygenator hydrogel with spatiotemporally feedback regulated hif-1α for accelerating diabetic wound healing

Diabetic wounds remain notoriously intractable due to a hostile microenvironment characterized by hyperglycemia, hypoxia, and oxidative stress. However, existing therapies often lack the ability to autonomously and sustainably remodel this pathological niche. Herein, a smart nano...

A federated learning model enables secure data sharing across regions in digital governance

To support secure collaboration among heterogeneous regional governance nodes, this study develops a governance-constrained federated learning model for cross-regional data sharing. Different from conventional federated learning security frameworks that separately deploy privacy...

Genomic insights into Bacillus velezensis FB-4 as a multifaceted biocontrol agent against Valsa canker caused by Valsa pyri on Korla fragrant pear

Pear Valsa canker, caused by Valsa pyri , poses a severe threat to the sustainable cultivation of Korla fragrant pear. The environmental concerns associated with chemical fungicides have driven the search for biological control alternatives. Endophytic bacteria represent a promis...

Attainable Second Support Weights of Binary Second-Order Reed--Muller Codes

For every dimension, we determine the exact set of support sizes attained by two-dimensional subcodes of the binary second-order Reed--Muller code. Necessity is expressed through an explicit compatibility system for the zero-frequency Walsh coefficients and polar ranks of the thr...

Rapid purity and charge-variant analysis of bispecific antibodies using microfluidic capillary electrophoresis-mass spectrometry

Bispecific antibody (BsAb) therapeutics have the ability to bind two targets simultaneously, which opens up new pathways for disease treatment. BsAbs consist of distinct heavy and light chains that need to be assembled correctly to form the appropriate heterodimer. However, durin...

Patient knowledge, attitudes, and practices regarding postoperative patient-controlled analgesia: a cross-sectional study using structural equation modelling

Effective postoperative pain management is crucial for recovery, and Patient-Controlled Analgesia (PCA) provides an important self-administration method for pain relief. However, inadequate understanding can hinder its optimal use. Therefore, this study aimed to explore patients’...

Reconfiguring handed shape-morphing and actuation in hydrogels via light-encoded rapid expansion

Reconfiguring handedness in synthetic systems with spatiotemporal control and reversible behavior remains a fundamental challenge in bioinspired robotics and materials science—especially in structurally homogeneous materials that lack intrinsic chirality. Here, we demonstrate hom...

Spectral Separation and the Non-Symmetric Strong Spectral Property for Looped Double Paths

We classify exactly when a looped double-path zero--nonzero pattern allows the non-symmetric strong spectral property (nSSP). The structural core proves that a real symmetric irreducible tridiagonal matrix with one nonzero diagonal entry has the nSSP exactly when the two Jacobi a...

Injectable platelet-rich fibrin improves clinical, biochemical, and microbiological outcomes in periodontitis: a 6-month split-mouth randomized controlled trial

The study aimed to investigate the effects of scaling and root planing (SRP) in conjunction with injectable platelet-rich fibrin (i-PRF) in patients with periodontitis (Stage II–III, Grade B) 1, 3 and 6 months following the treatment. Using the “split-mouth” design, 30 patients w...

Adaptive job scheduling and resource allocation for industrialized construction processes using digital twin and reinforcement learning

Construction processes can be disrupted by unforeseen operational disturbances, such as waiting for shared machines, insufficient workers, material unavailability, and workstation idleness. Such disturbances are difficult to mitigate through predefined schedules alone, as effecti...

Paley Two-Edge Switching for Proper Transposed Sesqui Arrays

For every odd prime power q congruent to 3 modulo 4 with q ≥ 11, we construct an exact-parameter proper transposed sesqui array. The construction crosses two edges of a classical Paley matching. Five quadratic-character conditions preserve the required concurrences, while a nonze...

Causal-Cone Saturation in Sequential Causal Growth: Independence, Clock Suppression, and Record Erasure

A causal order fixes a conformal class and hence a maximal local cone, but it does not by itself force a massless gauge field to propagate on that cone. We formulate the difference as a saturation problem, and show first that it is real: within the regular local constitutive clas...

Project Thalamus Technical Whitepaper: An Authorship Gate Between Clients and Language Models

Language models recompute answers from scratch on every request. Asking a question whose answer was already reviewed and approved by a human still burns full compute time and introduces subtle phrasing drift. Standard response caches attempt to fix this, but because they cache au...

Fabry Disease: An Updated Perspective and Review of Treatment and Therapies

Fabry disease (FD) is a progressive, multisystemic, X-linked lysosomal storage disorder that when untreated leads to decreased quality of life, chronic pain, and end organ disease; however, advances in therapy have significantly altered its original natural history. This paper br...