Research works

Metabolomic profiling reveals distinct and shared biology in COPD and IPF

Chronic Obstructive Pulmonary disease (COPD) and Idiopathic Pulmonary Fibrosis (IPF) are chronic pulmonary disorders with distinct pathologies but shared risk factors. Metabolomics may provide insights into mechanisms. To identify metabolites associated with COPD and IPF, and to...

Hotter days, smaller ranges: Air temperature constrains livestock movement and space use in Mediterranean rangelands

Livestock has become the dominant large herbivore guild in most rangelands worldwide. Current climate adaptation frameworks emphasize extreme climatic events, although the extent to which these episodic drivers capture the environmental conditions shaping animal behaviour remains...

A Nonsplit Special 2-Group Extension Governed by the 2×2 Matrix-Multiplication Tensor

This paper determines the extension structure of the full linear stabilizer of an explicit configuration of 1,024 six-dimensional subspaces over the binary field. The configuration was introduced in the preceding paper Exact Linear Symmetry of a Four-Core Rank-Metric Sunflower Co...

From Intelligibility to Finite Cosmic Lineage

This preprint develops a deductive approach to cosmogenesis that asks how far cosmological structure can be constrained before a particular dynamical model is chosen. Its sole generative premise is physical intelligibility from within a universe without an external observer, rese...

3D seismic imaging of a fracture damage zone controlling reservoir compartmentalization at the Raft River EGS using multi-azimuth walkaway VSP

Accurate imaging of steeply dipping fracture zones in crystalline enhanced geothermal systems (EGS) is critical for constraining permeability architecture and guiding stimulation design. However, such structures remain poorly resolved by conventional surface seismic methods. We p...

Efficacy and safety of PD-L1 versus PD-1 inhibitors as consolidation therapy following concurrent chemoradiotherapy for unresectable stage III non-small cell lung cancer: a real-world retrospective study

The PACIFIC trial established consolidation immune checkpoint inhibitors (ICIs) following concurrent chemoradiotherapy (cCRT) as standard care for unresectable stage III non-small cell lung cancer (NSCLC). Both programmed cell death protein 1 (PD-1) and programmed death‑ligand 1...

Light‐Enhanced Chloride Transport by Thiourea‐Appended Molecular Motor

ABSTRACT The regulation of solute transport across lipid bilayer membranes is central to many biological processes and is typically mediated by protein transporters that dynamically respond to stimuli. The development of artificial systems that emulate such responsive behavior re...

Identifying active surfaces for C2 decomposition relevant to the FC-CVD CNT synthesis process

Selecting for high quality carbon nanotube (CNT) growth during the floating catalyst vapour deposition (FC-CVD) synthesis process remains a challenge due to the coupling of physical and chemical phenomena inside the reactor. While there is evidence implicating C2 species as the p...

A Twin-Gap Existence Conjecture

Constructive refinement of the Twin-Prime Propagation Conjecture. Conjectures that every large lower twin prime has a productive gap of size o(t), yielding a generative map on twin primes.

Quantitative representation and parameter weight analysis of dimple in multi-point flexible die forming process

To investigate dimple defects in the multi-point flexible die stretch forming (MPFDSF) process, this study focuses on the quantitative characterization, prediction, and control of dimples in 2024-O aluminum alloy spherical parts. Based on ABAQUS finite element simulations, the th...

Visual Lexicon, Grammar and Syntax of Underwater Paintings: Cristian Mesa Velázquez's Works vs Pre-Raphaelite Symbolism and the Hyperrealism of Samantha French (with Italian translation included)

This article examines how three bodies of work, consisting of selected works by the Pre-Raphaelite painters of the nineteenth century, the contemporary American painter Samantha French, and the Cuban-born, Spain-based painter Cristian Mesa Velázquez, use water and the submerged b...

Watching Others Win: How the Ambiguous Benefits of Loyalty Programs and Members’ Social Observations Shape Their Coping Strategies

Terms and conditions (T&Cs) in tourism loyalty programs are increasingly ambiguous, yet loyal members actively negotiate for preferential treatment. This research extends the firm-centric paradigm by examining how social observations of customer-initiated preferential treatment o...

EuroMillions Breakthrough Mining — 2128 Sources, 16618 Leads Extracted — E8 Intelligence Research

Mined 2128 lottery+quantum breakthroughs. Extracted 16618 leads across 13 categories. 14457 high-value leads found. Categories: {"CORRIDOR": 1391, "FORMULA": 1228, "GEOMETRIC": 793, "FORWARD_ATTEMPT": 1470, "QUANTUM": 1690, "TIMING": 228, "CELESTIAL": 1315, "GEMATRIA": 1402, "CON...

Emerging orthobunyaviruses: genomic diversity, reassortment, and expanding public health risks

Abstract Orthobunyaviruses (family Peribunyaviridae ) represent one of the most diverse groups of arboviruses, infecting humans, livestock, and wildlife worldwide. Despite their broad geographic distribution and ecological complexity, most orthobunyaviruses remain poorly characte...

Redactional Evolution and Geometric Bounds: A Unified Information-Theoretic Framework for Persistence Failure in Biological and Computational Systems

This seminal BRPT paper presents a groundbreaking, unified information-theoretic framework that models Redactional Evolution as the primary engine for preventing persistence failure across diverse biological and computational systems. Challenging conventional ‘Cold Logic’ models...

P1.183. Salvage Surgery and Conversion Surgery for Esophageal Cancer in Patients Aged 80 Years or Older

Abstract Topic Esophageal Cancer: Surgical Treatment of Esophageal Cancer Background With the rapid aging of the population, esophageal cancer in individuals aged 80 and older continues to increase. Conversely, with recent advances in multidisciplinary treatment, including novel...

Examining the influence of ethnomodelling as second-order construct on students' problem-solving ability: the role of epistemological belief and mathematics self-efficacy

Purpose The study aims to investigate the mediating role of mathematics self-efficacy and the moderating effect of epistemological belief on the nexus between ethnomodelling as a second-order construct and students' problem-solving ability. Design/methodology/approach Adopting a...

E8 Harmonic Phase Locking Threshold for Quantum Coherence Emergence — E8 Intelligence Research

When 132 Hz base frequency harmonics align with phi-scaled E8 root vector projections, a critical threshold emerges where quantum superposition states lock into stable geometric configurations. This E8 Phase Locking Threshold (E8-PLT) occurs at precisely 144 harmonics, where phi^...

P1.172. Comparison of Intraoperative Complications in Obese vs Non-Obese in Oesophageal Cancer Surgery

Abstract Topic Esophageal Cancer: Surgical Treatment of Esophageal Cancer Background Obesity is a substantial public health issue. A high body mass index (BMI) can increase surgical technical challenges, resulting in higher rates of intraoperative and postoperative complications....

Carnauba-beeswax oleogel coatings with rosemary extract as an active system for safer fried chicken

Reducing oil uptake, retaining moisture, minimizing oxidative rancidity, and mitigating toxic compounds, such as advanced glycation end-products (AGEs) and 5-hydroxymethylfurfural (5-HMF), have become major priorities in the food industry. Herein, this study aimed to evaluate car...