Research works

Class- and dose-dependent heterogeneity in the risk of medication-related osteonecrosis of the jaw among antiresorptive agents: a nationwide new-user cohort study using Korean National Health Insurance claims data

Antiresorptive agents are widely used to treat osteoporosis and skeletal complications of malignancy, but long-term use can lead to medication-related osteonecrosis of the jaw (MRONJ). No nationwide Korean study has directly compared oral and intravenous bisphosphonates with low-...

An energy-saving strategy for edge data center clusters driven by deep learning and real-time load forecasting

To address energy-saving optimization in edge data center clusters under high-density cabinet deployment, dynamic workload fluctuations, and increasingly strict energy-efficiency constraints, this paper proposes a collaborative energy-saving strategy driven by deep learning and r...

Impact of noncommunicable diseases (NCDs) on COVID-19 mortality: A study of risk factors and outcomes in a Southeast Asian population

This study investigated the association between noncommunicable disease (NCD) comorbidities and clinical outcomes of COVID-19 infection, and examined the effects of demographic factors, vaccination status, and symptom presentation on COVID-19 disease fatality in Brunei Darussalam...

An explainable machine learning model based on quantitative HRCT parameters for identifying bronchoscopically confirmed airway stenosis in tracheobronchial tuberculosis

Airway stenosis is a frequent and serious complication of tracheobronchial tuberculosis (TBTB), leading to chronic airflow obstruction and reduced quality of life. However, no individualized predictive model currently exists to assess airway narrowing risk in these patients. This...

Bilateral internal carotid artery dissection and occlusion in Eagle syndrome treated with emergency single-session bilateral carotid artery stenting: a case report

Eagle syndrome (stylocarotid variant) is a rare but potentially life-threatening cause of internal carotid artery (ICA) dissection and ischemic stroke. Bilateral ICA dissection due to Eagle syndrome has been treated with both staged and single-session bilateral carotid stenting e...

Children as citizen scientists at EXPO 2025 clarify geometry-dependent feeding mechanics in mushroom corals

Abstract Ciliary-mucus feeding of free-living Fungiidae (mushroom corals), in which coordinated ciliary currents transport food particles toward the oral aperture, remains poorly characterised despite over a century of descriptive study; understanding the physical determinants of...

Mathematical and Theoretical Foundations of the Basic Phase-Transport Equation: A Unified Differential, Covariant, and Path-Functional Theory

This paper studies phase formation, continuous comparison, and cross-state transport when the observation map varies with the state of an observer. Starting from the classical model y = h(x), we prove that a complete representation of a nontrivial family of observation maps requi...

The Verdict Is a Function of the Slice: Auditing a Published Quantization Superiority Claim

A published comparison is read as deployment guidance, and what that reader needs is that its verdict holds on the files they are about to download. Two moves are supposed to make such a reading trustworthy: fix what will be read before the data exist, and reproduce it on a secon...

The Information Isomorphism Law: A Meta-Law Spanning Ontology and Epistemology ——Tracing the Necessary Premise from the Cross-Disciplinary Success of the Scientific Discovery Operating System

The Scientific Discovery Operating System (Tang, 2026g, 2026r) has been successfully deployed across six completely independent disciplines, yet a fundamental question has never been systematically addressed: Why is this operating system effective? This paper's answer is: because...

Third-Person Epistemology: Information Isomorphism Epistemology and the Objective Foundation of Testability —From "I Think" to "Anyone Running the Code": How an Ontological Fact, Rigorously Calibrated on Truth-Known Systems, Proactively Verified on Truth-Unknown Systems, Supported by Convergent Evidence Across Six Disciplines, and Independently Confirmed Through Tool Replaceability, Legislates for Epistemology

This paper argues that Information Isomorphism Epistemology completes a paradigm shift in epistemology from the first person to the third person. Since Descartes, epistemology has been constructed in the first person—"I think," "I posit," "I see." When two "I"s reach conflicting...

The Regime Nuclide Map (I): Cross-Property Verification, Two-Dimensional Structure, and Network Update of the Confirmed Breakpoint Network ——Predictive Test and New Discoveries Based on the Nuclear Shell Regime-Switching Theory

The nuclear shell regime-switching theory (Tang, 2026v–y) predicts that the confirmed breakpoint network should be consistently established across independent physical quantities. This paper verifies this prediction for the first time and discovers new structures guided by the th...

Regimes Matter: Regime-Based Dynamic Asset Allocation Using Neural Networks

We study Merton's optimal portfolio problem in a market responsive to macroeconomic regimes, as characterized by VIX. Instead of solving the traditional Hamilton-Jacobi-Bellman equation, we train an artificial neural network (ANN) to learn the optimal allocation as a feedback fun...

Information Isomorphism Epistemology: From the Factor Hierarchy Law to the Reconstruction of Knowability —How the Establishment of an Original Epistemological Operating System Renders Kant's "Thing-in-Itself" Unnecessary

This paper presents the establishment process of an original epistemological system—Information Isomorphism Epistemology—and its philosophical consequences for Kantian agnosticism. This system consists of four components, each with an independent origin and irreplaceable demonstr...

Light – The Absolute Measuring Tool

This article analyzes the relationship between two Cartesian coordinate systems, each linked to an inertial reference frame (IRF), when these are in relative motion. Building on the L-ARF framework, it is assumed that communication between the systems occurs via light signals tra...

A Möbius-Scale Spinor Lift of Lorentz Kinematics: The Contained-Volume Law for Four-Momentum

Lorentz transformations are linear on Minkowski spacetime but induce Möbius maps on velocity, null-direction, celestial, and spinor ratios. Starting from this correspondence, we introduce the active model lift B = λA ∈ GL(2,ℂ), with A ∈ SL(2,ℂ) and κ = |λ|. The scalar factor does...

Preserving Participant Meaning in AI-Mediated Multilingual Qualitative Research

<ns5:p>Artificial intelligence is rapidly entering multilingual qualitative research through automated transcription, translation, coding, summarisation and quotation editing. Existing scholarship has examined many of these practices separately. Yet qualitative claims are usually...

Rb-Sr and U-Pb geochronology of neoblasts and porphyroclasts constrain movements along reactivated segments of the Outer Hebrides Fault Zone, NW Scotland

The crustal-scale Outer Hebrides Fault Zone (OHFZ) (NW Scotland) was initiated as a Stenian-Tonian (1040-950 Ma) ductile thrust, as determined by published U-Pb dating of syn-kinematic apatite. Thrust-related mylonites were then reactivated to form phyllonite belts during success...

Synergistic effects of acetic acid and sulfate on the degradation of ternary and alkali-activated concretes

Degradation of concrete structures exposed to silage effluent is primarily caused by the organic acids destabilising calcium-bearing phases in the cementitious materials. The performance of a ternary cement (Portland cement, ground granulated blast-furnace slag (GGBS) and silica...

PETCS — An entropic and dynamical framework for the early warning of critical transitions

We present PETCS (Predictive Entropic Theory of Complex Systems), an interpretable framework for the early warning of critical transitions in stochastic systems. The method integrates three elements: (i) state reconstruction via Takens embedding, where the assumptions and data qu...

A Privacy-Preserving Explainable Artificial Intelligence Hybrid Framework for Abnormal Network Traffic Identification and Intelligent Threat Detection

Abstract The rapid evolution of cyber threats, the widespread adoption of encrypted communications, and the increasing complexity of enterprise, cloud, edge, and Internet of Things (IoT) environments have exposed the limitations of conventional intrusion detection systems in accu...