Research works

The Big Stretch: Regulated Accumulation Beyond the Big Stretch

Contemporary cosmology is confronted by a growing collection of unresolved tensions, including discrepancies in measurements of the Hubble constant, anomalies in large-scale variance distributions, questions surrounding dark energy evolution, and the persistent challenge of recon...

A Validated Macro‐Scale CFD Thermal Framework for a Temperature‐Controlled Coffee Fermentation Bioreactor: Integrated Heat‐Transfer Simulation and Experimental Analysis

ABSTRACT Temperature exerts a critical influence upon coffee fermentation, driving microbial metabolic pathways, acidification kinetics, and post‐harvest bean quality. This study presents an integrated computational fluid dynamics (CFD)–experimental validation framework to analyz...

Fiber optic-based magnetostrictive sensor for monitoring pipe wall thickness

This article presents a novel sensor concept for continuous long-term monitoring of pipe or tank wall thickness that is based on strain measurements in a magnetostrictive material. The proposed sensor detects wall thinning in pipes or tanks by monitoring magnetic flux leakage (MF...

Environmental DNA Metabarcoding Reveals the Variations in Fish Diversity Across the Yangtze River Basin and the Effects of the Three Gorges Dam

It is imperative that freshwater fish biodiversity research incorporates diverse components, encompassing taxonomy, phylogeny and function, alongside multifaceted facets, including richness, divergence and regularity. This comprehensive approach is essential to facilitate a more...

Clinicopathological characterization and prognostic significance of HER2-low expression in endometrial cancer: a ProMisE molecular classification-based analysis

Antibody–drug conjugates have renewed interest in tumors with low-level HER2 expression. However, the clinicopathological distribution and prognostic significance of HER2-low status in endometrial cancer, particularly across ProMisE molecular subtypes, remain uncertain. This sing...

Experimental Investigation of Mechanical Properties of 3D-Printed Components Fabricated from Waste Plastic Extruded Filaments

Abstract The exponential global growth of post-consumer plastic waste poses severe environmental and socio-ecological challenges, necessitating innovative, decentralized recycling strategies. Simultaneously, the rapid industrial and domestic proliferation of Fused Deposition Mode...

Clinical Application of Circulating Tumor DNA in Surgically Treated Esophageal Squamous Cell Carcinoma

Background: Esophageal squamous cell carcinoma (ESCC) is associated with a high recurrence rate and is one of the most aggressive malignancies. Recurrence is mainly detected via imaging modalities; however, postoperative imaging surveillance has disadvantages, including reduced s...

MTAP deficiency in lung cancer cells enhances proliferation and migration and increases vulnerability to bone metastasis

Lung cancer continues to be the leading cause of cancer-related death worldwide. The advent of molecular targeted therapies has significantly changed the treatment landscape. Therefore, identifying new molecular targets is essential for the development of more effective treatment...

XR in cultural heritage: a comparative study of motivation, presence, and engagement across 360° virtual tours, VR, and AR at the archaeological site of Villa Regina

Abstract As immersive technologies gain prominence in cultural heritage, understanding their specific experiential qualities has emerged as a central research challenge. This study presents a rigorously controlled comparative analysis of three immersive systems: virtual reality (...

Dysfunctional romantic beliefs of heterosexual women undergraduate students: the role of traditional media and social media

This study aimed to explore dysfunctional romantic beliefs among women undergraduate students and the meanings they attribute to romantic messages received from traditional media and social media. Using a qualitative research design, twenty heterosexual undergraduate women partic...

[Au 4 (dppb) 3 ] 2+ – A Planar Gold Cluster with Bright Excitation Wavelength Dependent Emission

ABSTRACT The reaction of dppb(AuCl) 2 and InCl gives the [Au 4 (dppb) 3 ] 2+ cluster where the four gold atoms are arranged in a deltoid. This contrasts all known [Au 4 ] 2+ clusters which exclusively form tetrahedral structures. Single crystals of the title compound luminesce wi...

Confiding in a maven or a charmer? Impression management behavior of artificially intelligent conversational agents and consumer self-disclosure

Purpose Data-driven hyper-personalization promises stronger consumer relationships, yet growing privacy concerns and regulations limit marketers’ access to consumer data. In this context, voluntarily self-disclosed consumer information becomes critical for creating mutual value a...

Clinical insights into catathrenia: A real-world analysis from a tertiary sleep center

INTRODUCTION: Catathrenia is a rare sleep-related breathing disorder marked by groaning during prolonged expiration, often underrecognized or misdiagnosed as obstructive or central sleep apnoea (OSA or CSA) or parasomnia. Understanding its clinical and polysomnographic features i...

PFUSRC‑166 Topological Unfolding from 0 to 1: Mathematical Validation and Closed‑Loop Confirmation of the PFUSRC System's Foundational Axioms

This paper takes the infinite product constant c_{Pell } ≈0.58058 from the Stevenhagen conjecture as its point of entry, conducting a reverse structural isomorphism comparison from a mathematical phenomenon back to the foundational axioms of the PFUSRC system. The constant is def...

Magnetothermally Responsive Mesoporous Silica Nanocarriers: Materials Design, Thermoresponsive Gates and Controlled Drug Release

Magnetothermally responsive nanocarriers represent a promising platform for spatio-temporally controlled drug delivery by combining alternating magnetic field (AMF)-induced heating with thermally triggered cargo release. Among the available architectures, magnetite-core/mesoporou...

Tricking Turing: How to Build a Geometric Checkerboard on Living Tissue

The snake’s head fritillary (Fritillaria meleagris) displays one of the rarest pigmentation motifs in the plant kingdom: a high-contrast checkerboard of alternating purple and white domains on its tepals. Standard reaction–diffusion theory does not generically produce this patter...

Prognostic value of systemic immune‐inflammation index and systemic inflammation response index with maternal gestational diabetes mellitus: A systematic review and meta‐analysis

OBJECTIVE: Mounting evidence indicates that the systemic immune-inflammation index (SII) and systemic inflammation response index (SIRI) might be associated with the risk of gestational diabetes mellitus (GDM). However, existing findings remain inconclusive. This systematic revie...

Vernonia cinerea Extract and Its Silver Nanoparticles in the Making of Indigenous Eyeliner: A Formulation and Evaluation Study

Background, Vernonia cinerea Less. (Asteraceae), known as “Poovaamkurunnel” in Malayalam and “Sahadevi” in Sanskrit, is a medicinally significant herb documented in Ayurvedic and other traditional medicine systems for its anti-inflammatory, analgesic, antipyretic, and antioxidant...

IN VITRO EVALUATION OF ERK1/2 PATHWAY ACTIVATION BY BACOPA MONNIERI EXTRACT COMPARED WITH BACOPA MONNIERI EASITM IN A DIFFERENTIATED SH-SY5Y CELL LINE

Neuropathic injury is a pathological condition that occurs due to progressive neurodegeneration driven by oxidative stress, resulting in suppression of cellular survival cascade like Extracellular Signal-Regulated Kinase 1/2 (ERK1/2) pathway. The present study aims to evaluate th...

EuroMillions Breakthrough Mining — 1948 Sources, 14868 Leads Extracted — E8 Intelligence Research

Mined 1948 lottery+quantum breakthroughs. Extracted 14868 leads across 13 categories. 12781 high-value leads found. Categories: {"CORRIDOR": 1240, "FORMULA": 1080, "GEOMETRIC": 764, "FORWARD_ATTEMPT": 1312, "QUANTUM": 1526, "TIMING": 223, "CELESTIAL": 1165, "GEMATRIA": 1247, "CON...