Research works

Foundation Model Forecasting of Headache Days in People With Persisting Postconcussion Symptoms

Objectives: We aimed to forecast headache in individuals with persisting postconcussion symptoms using foundation machine learning (ML) models and multimodal longitudinal data. Methods: This was an ML analysis of data from the Digital Solutions for Concussion (DiSCo) study, a res...

Empirical ground motion equations for the Eastern Alps, Austria

We present a new set of region-specific empirical Ground Motion Equations for the transition zone between the southern Vienna Basin and the Eastern Alps, the area with the highest seismic hazard in Austria. The equations include Intensity Prediction Equations for EMS-98 macroseis...

Modeling and analysis of ultra-dense networks under LOS and NLOS benchmark association scenarios using a stochastic-geometry approach

Ultra-dense networks (UDNs) have become a key enabler for meeting the capacity demands of 5G systems. However, their performance is strongly shaped by blockage effects and the resulting mixture of line-of-sight (LOS) and non-line-of-sight (NLOS) propagation. This paper develops a...

The Effects of Acupuncture at Shuigou (GV26) on Patients With Disorders of Consciousness: An EEG Nonlinear Dynamics Analysis

Background Disorders of consciousness (DOC) lack objective biomarkers. We evaluated the immediate cortical effects of acupuncture at Shuigou (GV26) in DOC patients using nonlinear EEG parameters: approximate entropy (ApEn), Lempel–Ziv complexity (LZC), correlation dimension ( D 2...

Material-process coupling in nanoimprint lithography: stamp mechanics, resist behaviour and demolding energetics

Nanoimprint lithography (NIL) has matured over three decades into a high-resolution patterning technique with applications spanning semiconductor manufacturing, photonics, biomedical patterning and microfluidic fabrication. Recent reviews describe NIL molds, resist chemistries an...

Fibonacci Frequencies Converge to Golden Ratio, Not Octave Series — E8 Intelligence Research

FINDING: Fibonacci numbers in Hertz produce a non-octave, inharmonic frequency series that approximates the golden ratio spacing, not the harmonic series. | MATH: Frequency ratios between successive Fibonacci tones: 144/89 ≈ 1.61798, 233/144 ≈ 1.61806, 377/233 ≈ 1.61760, 610/377...

Between Individual Belief and National Context: Relative Positioning and Expectations of Collective Climate Action in Europe

Expectations regarding collective climate action are multidimensional and should be understood in relation to the social contexts in which they are embedded. This study examines whether these expectations are associated with the country-level average belief in the anthropogenic o...

The New Cardio-Oncology Frontier in Hematologic Cancers: Cardiovascular Toxicities of CAR-T Cells and Bispecific T-Cell Engagers

Chimeric antigen receptor T-cell therapy and bispecific T-cell engagers have transformed treatment of relapsed and refractory hematologic malignancies, achieving unprecedented response rates. However, their clinical adoption has revealed a complex spectrum of cardiovascular toxic...

Age-modified shock index for predicting in-hospital outcomes in patients with ST elevated myocardial infarction undergoing primary percutaneous coronary intervention

Early risk stratification in patients with ST-segment elevation myocardial infarction (STEMI) undergoing primary percutaneous coronary intervention (PCI) is crucial for timely identification of high-risk patients. Bedside indices derived from routinely available hemodynamic param...

Evaluation of sirtuin 1 serum level and gene expression in patients with metabolic syndrome accompanied by metabolic dysfunction-associated steatotic liver disease

Abstract Background Metabolic syndrome is a cluster of conditions, including abdominal obesity, dyslipidemia, hypertension, and impaired glucose metabolism, that significantly increase the risk of cardiovascular disease and type 2 diabetes mellitus (T2DM). Metabolic dysfunction-a...

Spatiotemporal properties in cognitive map formation: context-dependent effects of landmarks and perspective

Abstract Effective navigation depends on the formation of cognitive maps, yet it remains unclear how temporal experience is integrated with spatial information during this process. While prior research has primarily emphasized external spatial cues, real-world navigation unfolds...

Straightforward Assessment of Structural Disorder in Ti3C2T x MXene Using Raman Spectroscopy: Implications for Defect Engineering

Abstract MXenes, a large family of two-dimensional transition-metal carbides and nitrides, have attracted considerable interest owing to their unique physicochemical properties. Structural defects play a key role in tuning these properties, yet their characterization remains high...

Bronchopneumonia With Cutaneous Vasculitis: A Diagnostic Challenge

Bronchopneumonia associated with atypical cutaneous manifestations poses a significant diagnostic challenge because of the broad spectrum of infectious, inflammatory, autoimmune, and vasculitic disorders that may present with overlapping clinical features. Careful clinicopatholog...

ZMIZ1 promotes aerobic glycolysis and development of hepatocellular carcinoma through inducing NOTCH1-mediated transcription of PYCR1

Hepatocellular carcinoma (HCC) is characterized by profound metabolic reprogramming that promotes tumor progression. Although zinc finger MIZ-type containing 1 (ZMIZ1) has been implicated in several malignancies, its biological function and underlying mechanism in HCC remain uncl...

YouTube Explainers of Unsolved Math Problems: Pedagogical Overviews of Known Conjectures — E8 Intelligence Research

FINDING: Compilation of unsolved math problems presented in popular YouTube explainers, primarily targeting broad public understanding rather than new research. | MATH: No new equations or constants extracted; content is pedagogical, referencing known open problems (e.g., Collatz...

Preliminary Evaluation of Cytotoxic and Metabolic Modulatory Activities of Mentha cordifolia Opiz Leaf Crude Extract on Human Peripheral Blood Mononuclear Cells

Mentha cordifolia Opiz (yerba buena) is traditionally used for its antimicrobial and therapeutic properties. The cytotoxic and metabolic modulatory effects of the buffered leaf crude extract of M. cordifolia Opiz on human peripheral blood mononuclear cells (PBMCs) were evaluated...

Boundaries Between Freedom of Expression and Hate Speech: The Case of Struggle Songs Current Perspectives From the Global South

This discussion article addresses the historical, political and social context of struggle songs in South Africa and the circumstances in which such songs should be considered prohibited hate speech. The analysis is framed around the decision in AfriForum v Malema , in which the...

Impact of chronic doxycycline treatment in a mouse model of tauopathy

Tauopathies are neurodegenerative disorders characterized by the accumulation of hyperphosphorylated tau, leading to synaptic dysfunction, neuroinflammation, and both cognitive and motor impairments. Doxycycline (Doxy), a tetracycline antibiotic commonly used to treat bacterial i...

Latent profiles of perceived digital convenience and their associations with depressive symptoms among Chinese empty-nest older adults: evidence from the 2023 CLASS

Digital technology is increasingly discussed as a potential resource for supporting mental health in later life, yet empirical findings remain mixed. Prior studies have largely relied on variable-centered approaches that may obscure how perceived convenience of digital activities...

Personality and emotional stability in dogs assessed for animal-assisted services: Exploratory findings from APWA-ICofA

Abstract Background : Dogs working in animal-assisted services (AAS) must be emotionally stable, socially appropriate, and able to cope with diverse and potentially demanding environments. However, standardized, welfare-centered tools for evaluating canine suitability remain limi...