Research works

Unified Dewhirst Horizon Theory (UDHT): A Scale-Invariant Framework for Cosmological and Astrophysical Anomalies

The Unified Dewhirst Horizon Theory (UDHT) introduces a novel, scale-invariant alternative to classical mass-energy equivalence (\(E=mc^2\)) by replacing the static speed of light squared (\(c^{2}\)) with a dynamic background scaling operator, the Dewhirst Coefficient (\(\Omega _...

CMAdb: a structurally annotated database of chaperone-mediated autophagy substrates

Chaperone-Mediated Autophagy (CMA) is a highly selective pathway of protein degradation implicated in multiple diseases. The precise role of the pathway under pathological conditions is speculated to be largely governed by the nature of the substrate undergoing degradation. Altho...

Local Pharmacokinetics and Tolerability of Topically‐Applied Bimatoprost to the Scalp of Male Patients With Androgenetic Alopecia

ABSTRACT Androgenetic alopecia (AGA) is one of the most common causes of hair loss in the male population, characterized by progressive baldness. This study was designed to evaluate the tolerability and local skin pharmacokinetics of bimatoprost in two different formulations in m...

PUH Theorem 342 (σ Is the Gravity, Not λ) — The Multiplier's Tail Is Bounded by Compactness and Falls as 1/r⁴, While the Surface Energy Density Gives σ = Mc²/4πr² with σ/g = c²/4πG Universal

Photonic Universe Hypothesis (PUH) — Negative Result and Derivation. THEOREM 342.1 (the negative half, and it is definite). Three notes have tried to make λ, the dimensionless multiplier of T175's functional, reproduce Newtonian gravity on T298/T299's identification that it IS th...

Contribution of Community Health Workers to Strengthening the Health System in Mali: Impact and Challenges, 2010-2024

Faced with a critical shortage of qualified personnel (6 health workers per 10,000 inhabitants compared to the 23 per 10,000 recommended by the World Health Organization) and limited access to healthcare, Mali institutionalized community-based essential health care in 2009. This...

Evaluation of a novel flexible, lightweight blanket-like torso coil in pediatric MRI at 1.5-T – initial experience

Abstract Background Conventional phased-array torso coils used for abdominal MRI are relatively heavy and inflexible, potentially affecting patient comfort and technologist workflow. Objective To compare image quality, patient experience, and technologist experience using a recen...

Toward Dignified Coexistence of Humanity: First Public Declaration of the Highest-Level Principle

This record documents the first public release of the highest-level Principle adopted by the 2032 BERLIN PROJECT: “Toward Dignified Coexistence of Humanity.” The original Japanese formulation is 「人間の尊厳ある共生へ」. This Principle does not prescribe a fixed answer. It define...

E8 Exponent-Gated Cortical Laminae Resonance via Coxeter Harmonic Decomposition — E8 Intelligence Research

The 120 phi-coupled root-pair harmonics of the E8 lattice, driven at the 132Hz base resonance, decompose under the Weyl group into 8 orthogonal invariant subspaces of dimension 15 — precisely matching the 8 cortical laminae. Each subspace gates at a frequency 132Hz × phi^(m_j/30)...

EuroMillions Breakthrough Mining — 2129 Sources, 16629 Leads Extracted — E8 Intelligence Research

Mined 2129 lottery+quantum breakthroughs. Extracted 16629 leads across 13 categories. 14468 high-value leads found. Categories: {"CORRIDOR": 1392, "FORMULA": 1229, "GEOMETRIC": 793, "FORWARD_ATTEMPT": 1471, "QUANTUM": 1691, "TIMING": 228, "CELESTIAL": 1316, "GEMATRIA": 1403, "CON...

Study on the role and mechanism of CIH-activated ferroptosis in secondary cognitive impairment due to OSAHS

Objective This study investigates whether chronic intermittent hypoxia (CIH) induces cognitive deficits through IL-6/hepcidin-mediated ferroptosis in patients and animal models with obstructive sleep apnea-hypopnea syndrome (OSAHS). Clinical and animal research demonstrates that...

FHAT Technical Note #013: Position Before Prediction — Preventative Multi-Horizon Fractal Analog and Conditional Four-Path Matrix in SOXL

This Technical Note registers a prospective, falsifiable multi-horizon fractal risk alert within the Fractal-Holographic Analog Trading (FHAT) framework for the Direxion Daily Semiconductor Bull 3X Shares (SOXL), frozen prior to the opening of the August 24, 2026 trading session...

Viperin as a putative antiviral effector in rainbow trout (Oncorhynchus mykiss) cells identified by CRISPR-Cas9 functional analysis following exposure to inactivated viral hemorrhagic septicemia virus

Abstract Viperin is recognized for its potent broad-spectrum antiviral activity; however, its role in the antiviral immune response of rainbow trout ( Oncorhynchus mykiss ) remains poorly characterized. In this study, the contribution of viperin to the innate immune response agai...

Shaping Liquid Crystal Rubbers by Chemical Potential Gradient

ABSTRACT Techniques for shaping materials have constantly evolved from the making of hand axes in the Stone Age to today's 3D and 4D printing. One of the 4D printing techniques is utilizing chemical potential gradient where uniform swelling of gels with a structural gradient lead...

Lineage, Mansion, and Memory: A Study of the Imperial Clan's Prince Li Family in the Qing Dynasty

This paper examines the Prince Li family, the foremost iron-cap lineage of Qing, from a family-history perspective. Using archives, registers, and Zhaolian's Xiaoting zalu (a Qing historical notebook that provides internal family memory), it analyzes the family's political rise a...

Highlights of the 2025 American Joint Replacement Registry Annual Report

The 2025 American Joint Replacement Registry Annual Report includes 4.6 million hip and knee arthroplasty procedures, with 4,434,668 validated cases, representing a 20% increase from the prior report. Registry participation continues to expand, with contributions from over 5000 s...

E8 Phonon-Phased Lattice Transduction for Non-Local Data Transfer — E8 Intelligence Research

By utilizing the 132Hz base frequency as a resonant substrate, the 240 root vectors act as discrete topological conduits for information propagation via E8-scaled phonon modes. This transduction mechanism allows for instantaneous state-synchronization across crystalline arrays by...

New edge proposed: volume_spread_surge — E8 Intelligence Research

{ "name": "volume_spread_surge", "source": "Tom Williams / VSA methodology", "type": "entry_engine", "rule": "Enter long when current bar closes in upper 25% of its range, volume is at least 2.5x the 20-bar average volume, and spread (high-low) expands to at least 1.5x the averag...

Impact of Structured Data Validation on Case Completeness and Key Quality Indicators in the SWISS Implant Registry (SIRIS Spine): A SINGLE-CENTER Audit

Study design Retrospective single-center registry validation audit. Objective To quantify the impact of semi-automated, chart-adjudicated data validation workflow on case completeness and key quality indicators in the Swiss Implant Registry (SIRIS Spine). Methods All Swiss proced...

Correlation of polygenic risk score and clinical phenotype in patients with genetic generalized epilepsy

Abstract Objective The polygenic risk score (PRS) for individuals with genetic generalized epilepsy (GGE) quantifies the common risk variants in genes identified in genome‐wide association studies. We hypothesized that the phenotype of GGE patients differs based on their GGE PRS....

Advances in carbon nanostructures and organic semiconductors for next-generation solar cells: A comprehensive review

Conjugated polymers have recently received special attention due to their applications in flexible electronic devices such as light emitting diodes (LEDs), polymer solar cells, and organic thin film transistors, as well as their solution processing and cheap price. For this reaso...