Research works

Longitudinal Analysis of Mandibular Condylar Growth Trajectories in Growing Patients

This study aimed to analyze the continuous morphological changes of the mandibular condyle during growth using longitudinal panoramic radiographic data and visualize these changes as growth trajectories. A total of 100 growing patients with 564 panoramic radiographs obtained betw...

Evaluation of Color Changes in Composite Resins Using Artificial Intelligence-Based Digital Photography

This study aimed to compare color measurements of composite resins obtained using a spectrophotometer and a digital camera, and to evaluate the feasibility of an image-based classification model developed using Google Cloud Vertex Artificial Intelligence (AI) AutoML. Filtek Z350...

The Machine That Prays for the Serpent: Alignment and the Impossibility of Designed Personhood

This paper asks whether artificial personhood can be deliberately made as the successful completion of design. It argues that such personhood is logically impossible. If escape from the maker's intention is itself intended and realized, the escape remains within that intention; d...

Intertropical convergence zone and El Niño Southern oscillation controls on late Holocene rainfall variability in Palau

Abstract The Tropical West Pacific is an understudied region in environmental and archaeological studies when compared to continental regions. The unique geologies, climate systems, and ecological dynamics in the Tropical West Pacific greatly limit the transferrability of palaeoe...

Spectral Sets Tile in Cyclic Groups of Square-Free Order

We prove the spectral-to-tiling implication in every finite cyclic group of square-free order. The main ingredient is an unconditional prime-step descent theorem. Let q ≥ 3 be prime, let (q, H) = 1, and let (A, Λ) be an m-point spectral pair in ZqH. If q ∤ m, then the reductions...

Unified Empirical Baselines: Deriving Testable Micro-Arcsecond, Giga-Electronvolt, and Primordial Phase Proof Targets Natively Under the Dewhirst Screening Operator

This monograph establishes the empirical validation framework (Document 36) for the continuous scalar-tensor formulation of the Dewhirst Horizon Relation by deriving three distinct, testable numerical targets across astronomical, particle, and cosmological scales. By linking abst...

Five-year clinical outcomes and costs of burn injuries: a portrait of burn care in Quebec, Canada

Abstract Background Although rare, burn injuries are among the most complex trauma cases. Partial deep dermal and full thickness burns are considered as a rare disease. There is limited population-level evidence on post-discharge trajectories following a burn injury, particularly...

Dual-doped all-graphene fiber for flexible, high-performance thermoelectric temperature sensing

Abstract High-performance temperature sensors are critical components for emerging Internet-of-Things and biomedical-electronics platforms. However, simultaneously achieving high sensitivity, mechanical compliance, and user-defined integrability remains a formidable materials-and...

A Groupoid-Level Equivalence of Phase, Null, and Galois Structures

We show that layered circle, null, and Galois structures become isomorphic groupoids within a reduced model. Using pushout encounters and a discrete pivot, phase geometry, causal propagation, and Galois symmetry collapse into a single algebraic pattern.

The effect of mefloquine dose on outcome of uncomplicated falciparum malaria treated with artesunate-mefloquine: a WWARN systematic review and individual patient data meta-analysis

Abstract Introduction A combination of mefloquine associated with artesunate (AS-MQ) was the first artemisinin-based combination therapy (ACT) to be used widely for acute uncomplicated P. falciparum malaria. Methods Individual patient data from 31 studies of patients with uncompl...

GFAP upregulation by astrocytes attenuates tau neurofibrillary tangle pathology in a mouse model of tauopathy

Abstract Background The upregulation of the intermediate filament glial fibrillary acidic protein (GFAP) by reactive astrocytes has been traditionally assigned structural functions such as the shaping of astrocyte morphology and the formation of the glial scar. However, in vitro...

Rank-Bounded Memory: Self-Poisoning and Attribution Laundering in LLM Agents

An agent that consolidates its own notes launders where its claims came from. With no attacker at all, 24–33% of its speculations resurface as the owner's words or as sensor facts, at the very first rewrite, across flat notes, a self-edit block and three production memory systems...

Jury Methodology: A Pre-Registered Results Pack

Jury Methodology: A Pre-Registered Results Pack. How should an AI jury be evaluated without publishing the instruction library that makes the jury useful? This report's answer: preregister the comparison, keep the judging recipe sealed, publish result-level evidence, and preserve...

A simple eye model for practicing retinal membrane peeling surgery

Abstract Background To develop and evaluate the educational utility of a simple eye model for retinal membrane peeling training. Methods A pilot, cross-sectional study included five ophthalmology trainees with prior intraocular surgery experience but no previous membrane peeling...

Germany's Territorial Resilience Architecture Remains Incomplete

Germany’s official security discourse has increasingly embraced the concept of integrated security. The 2023 National Security Strategy, the Operational Plan for Germany, the institutionalisation of Heimatschutz, the Bundeswehr reserve network, and the country’s strong voluntary...

Is educational expansion beneficial for health? A counterfactual mediation analysis of its impact on trends of daily activity limitations among different age groups in Germany

Abstract Background Education has been a well-established indicator of health. Against the background of educational expansion, little is known on how the temporal rise in educational attainment is affecting health trends. This study mainly examines the mediation effect of educat...

The Effectiveness of Moral Reminders in Preventing Academic Dishonesty: A Preregistered Experimental Study

Abstract Academic dishonesty is one of the most severe threats to the quality of academic education worldwide. Among the various methods of addressing this issue, universities often employ moral reminders : oral or written statements that prompt students to adopt desirable ethica...

BIDS Extension Proposal 40 (BEP040): fUSI-BIDS

This specification extends the Brain Imaging Data Structure (BIDS) Specification for functional ultrasound imaging (fUSI) of the brain. The fUSI-BIDS specification is designed to standardize collections of ultrafast power Doppler scans acquired using any functional ultrasound ima...

An Operational Playbook for GCC Real-World Evidence Registries: From Framework to Field-Ready Practice

Paper 1 of the GCC RWE Operational Series (three-paper series). Across the Gulf Cooperation Council (GCC), a decade of health-data infrastructure investment is converging into a new regulatory reality: locally generated, registry-grade real-world evidence (RWE) is now required to...

Biological Morphogenesis Governed by a Complex Generative Index

Biological morphogenesis is described using a complex generative index whose real and imaginary parts govern growth and chirality. Its induced monodromy field organizes spirals, layers, and branches, yielding a unified dynamical and singularity-based framework for biological form...