Research works

Licensing a Compact Fusion Platform Under the Byproduct-Material Framework

Licensing a compact fusion platform under the United States byproduct-material framework (10 CFR Part 30), confirmed for fusion by the 2023 NRC determination and the ADVANCE Act. The materials-oriented, Agreement-State-administrable, graded path suits a machine whose only signifi...

CitraNav: A Lightweight Navigation Method Using Spatiotemporal Information Voxel Mapping and Model Predictive Path Integral Control for Complex Orchards

Canopy occlusion, dynamic vegetation, structural degeneracy, and implicit terrain risks make stable localization and task-adaptive planning difficult for resource-constrained orchard robots. This paper proposes CitraNav, a lightweight navigation method for global navigation satel...

From malpractice to patient safety: A framework for analysing harmful events, system vulnerabilities, and adaptive surgical expertise in neurosurgery – A Swiss perspective

Background The assessment of medical malpractice has traditionally focused on legal responsibility and individual accountability. However, legal classifications may provide only limited insight into mechanisms leading to patient harm and may therefore not fully support the develo...

GRAVITY — Foundational Research Record — Advocate Soumen Saha

This record preserves and presents an exploratory line of reasoning concerning gravity, developed by Advocate Soumen Saha from the ordinary observation that an apple falls. Rather than treating this familiar phenomenon as the end of explanation, the inquiry asks whether the pheno...

Nintedanib Treatment of Patients With Interstitial Lung Diseases: A Retrospective Study of Daily Clinical Practice

Background/Aim: Nintedanib, an antifibrotic drug, is expected to slow the progression of interstitial lung diseases (ILDs). This study aimed to evaluate the usefulness of nintedanib for patients with idiopathic pulmonary fibrosis (IPF) and progressive pulmonary fibrosis (PPF) who...

Establishing a Prognosis When Identifying Pathogenic Variants in Usher Syndrome/ DFNB ‐Related Genes: An Impossible Challenge?

As our results show that very few published variants could currently be considered causative of DFNB due to lack of precise clinical studies, strict and uniform criteria should be applied by authors publishing on USH/DFNB genes.

First‐Phase Ejection Fraction: A Novel Approach to Detecting Early Systolic Dysfunction in Hypertrophic Cardiomyopathy

ABSTRACT Background The assessment of stable coronary artery disease has been performed using the first‐phase ejection fraction (EF1) in previous research. However, the use of EF1 has seldom been employed in the evaluation of early left ventricular systolic dysfunction among pati...

Foundations of Trans-Planckian Horizon Lock Mechanics – Special Exposition: Resolving the Mathematical Anomalies, Fluid Turbulence Dynamics, and Geometric Ciphers of Leonardo da Vinci via Gauge-Invariant Spacetime Regularization

This exposition delivers the complete, integrated mathematical physics resolution to the historical, aerodynamic, fluid-dynamic, and geometric ciphers left by Leonardo da Vinci, establishing their underlying physical mechanics under the framework of Trans-Planckian Horizon Lock M...

Depression and Anxiety in Women Undergoing Therapeutic Abortion: The Effect of Spirituality

Objective: This study was conducted to determine the relationship between depression, anxiety, and spirituality levels in women who underwent therapeutic abortion.Materials and Methods: The sample of this descriptive and cross-sectional study consisted of 140 women who underwent...

Advances in Enzyme Immobilization and Its Application in the Degradation of Typical Emerging Contaminants

ABSTRACT Emerging contaminants (ECs), including pharmaceuticals and personal care products (PPCPs), endocrine‐disrupting chemicals (EDCs), pesticides, and polycyclic aromatic hydrocarbons (PAHs), have attracted increasing attention due to their persistent occurrence and potential...

The 5-Bit Eisenstein-Norm CRT: A 96 Ops/Cycle Inference Engine for Binary Silicon

This document presents a reduced arithmetic representation for the Eisenstein-Norm CRT framework. By decreasing the lane width from 10 bits to 5 bits (3 mantissa bits and 2 exponent bits), the number of independent lanes per 64-bit word doubles from 6 to 12, achieving a peak thro...

De-familialization of care and the emerging crisis of unmet needs among older adults in South Korea

Unmet long-term care (LTC) needs are a critical policy indicator for aging societies. Using repeated cross sectional data from the nationally representative National Survey of Older Koreans (2014 and 2023), we examined changes in unmet LTC needs among community-dwelling older adu...

Cultural determinants and strategic priorities for medication safety in acute care: a multidisciplinary Delphi study

Abstract Background Organisational culture, defined as the shared values, assumptions, and norms that influence behaviour within organisations, is widely recognised as a key determinant of patient safety in healthcare systems. Within acute care settings, medication safety represe...

Gut Microbiomes of Two Bamboo Locusts Reveal Divergent Metabolic Potentials

ABSTRACT The yellow‐spined bamboo locust ( Ceracris kiangsu ) and the green‐spined bamboo locust ( Ceracris nigricornis ) are two common bamboo‐feeding forestry pests in China. C. kiangsu has stronger migratory capacity and causes greater damage, yet comparative studies of their...

Early hormonal responses of irisin and nesfatin-1 following sleeve gastrectomy in women with obesity: A preliminary study

Laparoscopic sleeve gastrectomy (LSG) is an effective surgical intervention for morbid obesity, yet early hormonal changes contributing to metabolic adaptation remain underexplored. The objective of this study was to evaluate the early postoperative changes in the energy-regulati...

Golden Angle and Fibonacci Spirals: Optimal Seed Packing via Voronoi Hexagons — E8 Intelligence Research

FINDING: Sunflower phyllotaxis is governed by the golden angle (≈137.507°), producing Fibonacci spiral counts (13, 21, 34) that maximize seed packing efficiency; Voronoi tessellation of such patterns yields near-hexagonal cells, bridging discrete growth rules to continuous geomet...

A Control-Barrier-Certified Zero-Escape Safety Clamp for a Compact Spherical-Tokamak Breeder

A deterministic, control-barrier-certified safety clamp providing a provable zero-escape guarantee for the compact spherical-tokamak breeder operating envelope. A robust, disturbance-tightened control-barrier-function filter with a closed-form separable solution wraps an arbitrar...

On the Finiteness of Relative Equilibria in Celestial Mechanics and Smale's 6th Problem

This preprint provides an exhaustive 8-page mathematical monograph on Smale's 6th Problem (Steve Smale, 2000), dedicated to the finiteness of relative equilibria (planar central configurations) in the Newtonian N-body problem. Smale's 6th problem asks whether the number of relati...

Controls of Sediment Grain Size and Bedform Dynamics on Scour Variability in a Strait‐Influenced Tidal Delta

ABSTRACT Scour development around offshore monopiles in the Eastern Mouth Tidal Delta (EMTD) of the Qiongzhou Strait was investigated based on field observations of bathymetry, hydrodynamic conditions and sediment grain size. The results reveal pronounced spatial variability in s...

Quantum Field Architecture

The universe operates as a dynamic geometric substrate, a continuous, tension-bearing field whose stable and metastable configurations produce every particle, force, and interaction catalogued by modern physics. All quantum phenomena historically labeled "weird," "probabilistic,"...