Research works

Differential Effects of the Apelin Receptor Blockade by [Ala13]-Apelin-13 on Colonic Barrier Integrity and Hepatic Inflammatory Responses in Chemically Induced Colitis

The apelin receptor (APJ) is widely expressed throughout the body and plays important roles in the regulation of inflammation, oxidative stress, and tissue repair. Because APJ signaling is highly context dependent and may vary according to tissue type, inflammatory status, and li...

Association between sleep bruxism, awake bruxism, perceived stress and coping strategies among dental students: a cross-sectional study

Bruxism is a common condition that can adversely affect quality of life and may be associated with tooth wear, temporomandibular disorders, and failures of dental restorations. The aim of this cross-sectional study was to investigate whether sleep bruxism (SB) and/or awake bruxis...

SYSTEM EVOLUTION PROPOSALS (rlab #144) — E8 Intelligence Research

- Add a pipeline to automatically generate 2D/3D Coxeter plane projections of E8 using SageMath and overlay phi-harmonic spirals for angular alignment detection. - Integrate a module to cross-reference E8 symmetry numbers (240, 248, 30) with ancient metrology databases (Stoneheng...

Resynchronisation of the Biological Clock Using Exposure to Low Oxygen Levels in Humans: An Exploratory Study

Exposure to reduced oxygen levels occurs in several real-world contexts, such as during air travel or altitude exposure, and emerging evidence suggests that hypoxia may interact with molecular pathways involved in circadian regulation. This exploratory study investigated the effe...

Is Body Roundness Index a Predictor of Cancer Incidence and Mortality? A Prospective Cohort Study

ABSTRACT Body Roundness Index (BRI) is a novel measure of visceral and total body fat. Its association with multiple cancers and predictive value relative to Body Mass Index (BMI) remain unclear. The associations between BRI and the incidence and mortality (specific, overall and...

P1.048. 14 Years of Esophageal and Esophago-Gastric Junction Cancer Epidemiology in a National Cancer Center in México

Abstract Topic Esophageal Cancer: Other Background In 2022, the incidence of esophageal cancer was 11th, and mortality was 7th place. Mexico is a middle-income country, and incidence and mortality are not among the top 10, but we do not have a national cancer register, and the in...

Exclusion Interaction

This work presents a novel theoretical framework treating Pauli-driven atomic repulsion as an independent fundamental interaction, distinct from electromagnetism. We demonstrate that the Pauli exclusion principle generates a short-range, spin-dependent repulsive force mediated by...

Tumor-specific co-expression of ACTB and miR-138-5p in colorectal adenocarcinoma

Abstract Colorectal cancer (CRC) is the third most commonly diagnosed malignancy and the second leading cause of cancer-related mortality worldwide. The ACTB gene, traditionally considered a reference gene, exhibits transcriptional instability in colorectal cancer tissues. The pr...

Uncontrolled and Recurrent Epistaxis in an Adult: The Globulin Gap Clue

A 49-year-old man presented with recurrent epistaxis, gingival bleeding, vertigo, and severe anemia. Despite normal coagulation parameters, bleeding worsened after red blood cell transfusion and was refractory to standard therapy. A marked globulin gap on routine liver function t...

Haptoglobin is associated with nocturnal blood pressure non-dipping in children with chronic kidney disease

Abstract Background Blood pressure (BP) follows a circadian rhythm that depends partly on endothelial nitric oxide (NO) bioavailability. Cell-free hemoglobin rapidly scavenges NO, and haptoglobin functions as a capacity-limited plasma buffer facilitating hemoglobin clearance. Whe...

Hydrothermally synthesized Dy³⁺ doped SrZrO₃ nanophosphors for efficient white light emission and latent fingerprint detection

Environmental safety and energy conservation have emerged as the two most crucial fields in the past few years. This paper reports, the simple hydrothermal approach used to prepare Dy 3 + ions (1–9 mol%) incorporated SrZrO 3 nanopowders (NPs). A thorough investigation was conduct...

Development of a core competency evaluation indicator system for weight management nurses: a Delphi and analytic hierarchy process study

Weight management services increasingly require nurses to contribute to risk assessment, behavioural support, multidisciplinary coordination and long-term follow-up. However, there is limited consensus on the competencies required for nurses working in this emerging field. This s...

Unmet Needs of Adolescent and Young Adult Cancer Survivors Treated in West Virginia: A Qualitative Analysis of Open-Ended Survey Responses

Purpose: To characterize unmet supportive care needs among adolescent and young adult (AYA) cancer survivors in rural West Virginia. Methods: We conducted a cross-sectional survey of individuals diagnosed with cancer at ages 15–39 and treated within the West Virginia University H...

Fuelling the top – Metabolic control of shoot apical meristem function and plant development

Plant development relies on a complex network of transcription factors and hormone signalling pathways that guide pattern formation and developmental transitions in the meristems. Yet, how this core network is regulated to enable developmental plasticity remains poorly understood...

P1.103. Evaluation of the Efficacy of Local Therapy for Postoperative Oligo-Recurrence in Esophageal Squamous Cell Carcinoma

Abstract Topic Esophageal Cancer: Management of Metastatic Cancer Background Postoperative recurrence of esophageal squamous cell carcinoma (ESCC) is associated with poor prognosis. Among recurrent patterns, oligo-recurrence (OR) has attracted attention because long-term survival...

Multi‐Channel Holography Enabled by Interlayer‐Correlated Liquid Crystal Elements for Nested Optical Encryption

ABSTRACT Liquid crystal (LC) planar devices have emerged as an attractive ultra‐thin platform for optical encryption. However, most existing LC‐based holographic encryption schemes rely on conventional multiplexing strategies with limited design freedom and weak interlayer collab...

ELECTRONIC EVIDENCE IN CRIMINAL JUSTICE: CHALLENGES OF AUTHENTICITY AND ADMISSIBILITY

This article studies the problems of authenticity and admissibility of electronic evidence in criminal justice. Because digital technology is now used everywhere, electronic data such as emails, social media messages, bank records and video surveillance footage are increasingly u...

Deletion of P311 enhances regeneration in aged skeletal muscle

While aging results in marked decreases in the capacity of skeletal muscle to repair following injury, as well as increases in fibrosis, the pathways and factors that regulate these processes are poorly defined. P311/Nrep (P311) is a highly conserved protein known to promote fibr...

From Celestial Configuration to Effective Environment: A Formal Analysis of Medium, Delay and Individuation in Deep-Sea Life - The Deep-Sea Astrological Conjecture as a Conditional Thought Experiment

Any system that holds celestial states to influence life, whatever its empirical standing, implicitly assumes something very strong in physical terms: that the environment is transparent to external signals, so that the input received by an organism equals the celestial state its...

The Optimal Momentum State of Adam under Frozen Local Dynamics

Momentum gives Adam memory: its future is determined not only by the model parameters, but also by the first- and second-moment states inherited from earlier gradients. We ask a conditional question: with the current parameters and adaptive metric fixed, what first-moment state s...