Research works

Modification of Perilla (Perilla frutescens (L.) Britt.) Seed Protein via Physical Treatments for Enhanced Gelation Properties

Perilla (Perilla frutescens (L.) Britt.) seed protein, an underutilized resource derived from medicinal and edible plants, was subjected to ultrasound (400 W, 20 min), pH-shifting (pH 12.0, 1 h), and high-pressure homogenization (90 MPa, 3 cycles), applied individually or in comb...

Heterocyclic Molecular Passivators for Improved Stability and Efficiency in Perovskite Solar Cells

In recent years, organic–inorganic halide perovskite solar cells (PSCs) have rapidly emerged as one of the most promising third‐generation photovoltaic technologies, due to their high‐power conversion efficiency (PCE), low cost, and solution processability. The device performance...

Flexible Photochromic Synaptic Devices for UV Perception and Spatiotemporal Encoding

ABSTRACT Flexible synaptic devices with short‐term optical dynamics offer promising building blocks for low‐power and visualized neuromorphic perception, yet introducing time‐dependent weight update and visual readout remains highly challenging. Herein, we establish a universal s...

Support and destigmatization in early pregnancy loss in Spain

Abstract Early miscarriages are a frequent reproductive event, often silenced and shrouded in stigma. Feminist anthropology has pointed out how such losses challenge the widespread Euro‐American social representations of motherhood and pregnancy, as well as societal unease with d...

Hypertensive stretch regulates endothelial cell inflammation and apoptosis through ceramide metabolism

Hypertension and cardiovascular disease (CVD) are associated with elevated plasma levels of ceramides (Cer), a type of membrane sphingolipids (SPLs). Increased cellular Cer levels are known to cause vascular endothelial cell (EC) dysfunction. However, Cer metabolism changes due t...

Hyperspectral Technology: A Method Framework for the Estimation of Metal Content in Cobalt-Rich Crusts

Cobalt-rich ferromanganese crusts are an important deep-sea mineral resource, and the ore grade is a key indicator for evaluating their resource potential. Conventional ore-grade assessment relies on representative samples and extensive laboratory analyses, posing significant cha...

Repurposing Seleno-L-Methionine as a Pleiotropic Immunomodulatory Agent to Overcome TGF-β1/HIF-Driven Immune Evasion in Clear Cell Renal Cell Carcinoma: Mechanistic Insights and Translational Therapeutic Opportunities

Clear cell renal cell carcinoma (ccRCC) is a highly immune-evasive malignancy that exhibits limited and often transient responses to immune checkpoint inhibitors (ICIs) and remains a major challenge for emerging cellular immunotherapies, including chimeric antigen receptor (CAR)-...

Prenatal Test Selection After First‐Trimester Ultrasound Abnormalities Within a Centralized Genetic Counseling System in Japan

This study evaluated the association between first-trimester ultrasound abnormalities and prenatal test selection within a centralized genetic counseling system in Japan. Advances in ultrasound screening and the increasing use of non-invasive prenatal testing (NIPT) have expanded...

Evaluating PBE-D3/M06 for copper-catalyzed carbon chemistry: Kinetic barriers and mechanistic insights

Accurate prediction of activation barriers is essential for reliable mechanistic modeling of copper-catalyzed carbon conversion reactions yet remains challenging for conventional density functional theory. Here, we evaluate a hybrid PBE-D3/M06 approach for reaction kinetics on lo...

Screening of sarcopenia in long-term care facilities using wireless surface electromyography and deep transfer learning: a proof-of-concept study

Abstract Background Sarcopenia is prevalent in long-term care facilities (LTCFs) and is associated with falls, functional decline, and mortality. Aims This proof-of-concept study, within the I-COUNT pilot randomized controlled trial, evaluated the feasibility and diagnostic perfo...

Turning Failure into Success: Prosthetic Rehabilitation After Surgical Setback in Gingival Squamous Cell Carcinoma

Oral squamous cell carcinoma (OSCC) is a common malignancy that can develop from precancerous conditions such as oral lichen planus (OLP). This case report describes the clinical management and complication reporting of a patient with OLP who developed an exophytic lesion on the...

Mood Disorder Symptoms Among Medical Doctors in Romania: Prevalence and Associations with Suicide Risk and Quality of Life

Mood disorder symptoms represent an important but understudied mental health concern among physicians in Romania, with potential implications for quality of life and suicide risk. This cross-sectional study included 104 medical doctors. Validated self-report instruments were used...

Matrix‐Activated Aptamer Sensors for Human Serum Analysis

ABSTRACT Owing to their ease of operation, solution‐phase fluorescent sensors hold a crucial position among aptamer‐based detection tools. However, their performance is regularly compromised when exposed to increasing levels of blood fluids, such as human serum, which limits thei...

Bronchoscopic Ablation and Intratumoral Therapies for Lung Cancer: Expanding Local Treatment Beyond Surgical Resection

Advances in navigational bronchoscopy, robotic platforms, and intraprocedural imaging have transformed bronchoscopy from a diagnostic modality into a potential therapeutic platform for localized treatment of lung cancer. These developments are particularly relevant for patients w...

Colchicine for cardiovascular secondary prevention: evidence from recent trials and meta-analyses

PURPOSE OF REVIEW: Residual inflammatory risk remains an important driver of recurrent vascular events despite contemporary lipid-lowering and antithrombotic therapies. Low-dose colchicine is the first widely available anti-inflammatory therapy to be incorporated into contemporar...

Tunnel-form system as an ideal solution for seismic regions: a numerical study based on life-cycle cost analysis

Abstract The present study focuses on the evaluation of the life-cycle cost of concrete tunnel-form system through an innovative approach. Such life-cycle cost analysis accounts for the roles of different building components in generating injury, fatalities, and downtime. Using s...

A Structured Decision-Making Framework for Capability Gaps Resolution: Integrating MCDM and Constructive Simulation in Military Capability Planning

The paper presents a hybrid methodological framework for resolving military capability gaps by integrating Multi-Criteria Decision-Making (MCDM) and constructive simulation. The purpose is to enhance defense planning transparency and objectivity. Using the Analytic Hierarchy Proc...

Kleine Fragmentologie der Fotografie

Abstract Dieser Essay untersucht Modalitäten der Fragmentierung in der Fotografie: vom Riss über den Bruch bis hin zur Teilung von Fotografien oder Auflösung von Fotoserien. Fragmentierungen können in der Fotografie entweder aus zufälligen Schäden oder intendiert entstehen, wenn...

Integrating Environmental Value Into Mobility‐as‐a‐Service: Behavioral Insights for Sustainable Mobility Strategy

ABSTRACT Mobility‐as‐a‐Service (MaaS) offers an integrated solution for sustainable urban transport. However, user adoption remains limited, and individuals' valuation of environmental performance is poorly understood. This study empirically examined sustainability‐oriented prefe...

Identification of Pea Root Rot Pathogens and Transcriptomic Analysis of Pea Responses to Pathogen Infection

Pea root rot is a major soil-borne disease that threatens global pea production. In this study, diseased pea root samples were collected from Zhejiang Province for pathogen isolation and identification. The mycelial growth rate method was used to evaluate the sensitivity of the p...