Research works

Before the Oil: Suriname's Gold Economy as a Foreign-Exchange System (pre-registration)

Pre-registration, version 1.0, frozen on deposit. Institut Atlantique Sud Research Note No. 3. Gold is Suriname's principal declared export, and its proceeds are a source of foreign exchange the State repeatedly tries to channel into the domestic market. Offshore oil from Block 5...

YtrG is a functional part of the ytrGABCDEF operon and contributes to phenotypic heterogeneity in Bacillus subtilis

ABSTRACT The Bacillus subtilis ytrGABCDEF operon consists of the transcriptional repressor YtrA, the ATP-binding cassette transporter subunits YtrB, YtrC, YtrD, YtrE, and YtrF, likely forming two distinct transmembrane complexes (YtrB 2 CD and YtrE 2 F 2 ), and the small monotopi...

Workings of the Higgs Field: Vacuum, Goldstone Modes and the Force That Leaves the Weyl Orbit

The preceding volumes separated a Poincaré mass-label from a Weyl mass-coordinate, closed the ten-dimensional similitude orbit, and refused to licence the unified nouns left outside that closure. One of those nouns is the Higgs. Reynaud's letter adds, as a reading, a mass-gradien...

DHODH is the key target of the KDM4 inhibitor QC6352 in glioblastoma stem cells

Abstract Histone lysine demethylase 4 (KDM4) enzymes are frequently overexpressed in cancer and are considered to be promising therapeutic targets. QC6352, which is widely used as a best-in-class KDM4 chemical probe, shows potent antitumor activity across cancer models. Using com...

Creation and Validation of the Meaningful Experiences Measure for Museums

A new tool for measuring meaningful experiences in museums was developed, consisting of 15 items that explore various themes integral to meaningful visitor experiences. The tool is unidimensional, which facilitates its practical use by museum researchers for trend analysis across...

Decision-Path Inverse Reconstruction: Observed Decision Outcomes as Structural Constraints on Latent Decision Paths

This working paper proposes Decision-Path Inverse Reconstruction (DPIR), an inverse analytical operation within the Atlas Insight Method (AIM). DPIR treats an observed decision outcome not only as the endpoint of a judgment process, but also as structural information that constra...

Clinical Trial: Dupilumab Improves Eosinophilic Oesophagitis Outcomes Versus Placebo Regardless of Comorbidities or Treatment History in a Randomised Clinical Trial

BACKGROUND: Patients with eosinophilic oesophagitis (EoE) can present with differing disease characteristics, treatment resistance, and associated type 2 inflammatory comorbidities. We assessed the efficacy of dupilumab in subgroups of patients with EoE from the LIBERTY EoE TREET...

Safety and health of workers in post-disaster reconstruction: a scoping review and evidence map

Post-disaster reconstruction (PDR) is essential for restoring damaged communities, yet the occupational safety and health (OSH) of PDR workers remains poorly understood. Although PDR involves many familiar construction hazards, these risks arise under distinct conditions, includi...

Addendum: Magnetic field screening in hydrogen-rich high-temperature superconductors

In our paper 1 , we studied the magnetic response of H 3 S and LaH 10 superconductors to an applied magnetic field using Superconducting Quantum Interference Device (SQUID) magnetometry. Prof. Hirsch, in his Matters Arising entitled “On the Author Correction to “Magnetic field sc...

Inadequate antibody validation places substantial numbers of animal and human tissue samples at risk of waste

Lack of antibody validation by researchers frequently misdirects biomedical research, yet the ethical consequences—particularly avoidable use of animal and human biological materials—remain unquantified. Using focus groups ( n = 12), surveys ( n = 107), and systematic analysis of...

Highly multiplexed mammalian metabolic engineering with a shotgun approach

Mammalian metabolic engineering advances basic biology, bioproduction and cell therapy. However, as pathway complexity increases, so does the size of the combinatorial design space and required DNA constructs, rendering unbiased screens intractable. Here, we developed shotgun gen...

Physician- and Practice-Level Variation in Clinical Trial Participation Among Patients With Advanced Cancer

Importance Clinical trial enrollment is essential to advancing cancer care, yet participation among patients with advanced cancer remains low. While patient-level barriers are frequently cited, the role of health care delivery factors—specifically physician- and practice-level va...

Development of diagnostic reference levels and acceptable quality dose for computed tomography in an Indian tertiary care center

Background Computed tomography (CT) contributes substantially to medical radiation exposure, making diagnostic reference levels (DRLs) important for dose optimization. This study aimed to establish preliminary institutional DRLs and evaluate acceptable quality dose (AQD) at an In...

Beyond Board Governance: Does the External Governance Ecosystem Enhance Corporate Value in Emerging Markets? Evidence from Listed Nigerian Banking Institutions

Purpose This study investigates whether the external governance ecosystem enhances the corporate value of listed Nigerian banking institutions. Moving beyond the traditional board-centric approach, it examines the influence of regulatory oversight, external audit quality, and env...

State of Stress in Subduction Zone Forearcs: Influence of the Mantle Wedge Corner and Serpentinization

Abstract We investigate the role of the elasticity and density of the forearc mantle wedge corner on the stress distribution in the forearc region of subduction zones, using numerical quasi‐2D lithospheric deformation models for the Cascadia, Nankai, NE Japan, and Costa Rica subd...

Angular momentum drives proton-rich nucleosynthesis in hyperaccreting neutron stars in common envelopes

Abstract Interacting binaries, especially for massive star systems, produce a wide range of exotic systems including X-ray binaries and merging neutron star systems. In the rapid expansion as a star moves off the main sequence (core hydrogen exhaustion), the star can engulf its c...

Higher frequency of homologous chromosome pairing in adult endothelial cells as compared to neonatal endothelial cells

During mitosis, pairing of homologous chromosomes can be detrimental and has been correlated with gene misregulation, chromosomal aberrations, and various pathological diseases. We previously demonstrated that homologous chromosomes are spatially segregated, or antipaired, in neo...

V₀ Disappearance Theory: Master Theory Record v1.6b — Proof-Provenance Closure, Bounded Inheritance-Completeness, and Final Bibliographic Hardening

This technical research record consolidates the V₀ Disappearance Theory through the DT0–DT5R, KMA0–KMA5, RSP0–RSP15, GBO0–GBO10, CS0–CS15, and subsequent REOPEN/ordinary-BSM competitor-analysis stages.Version 1.6b adds three principal layers of hardening. First, it audits structu...

The role of retinal flow in walking

Both visual direction and optic flow have been implicated in walking toward a goal in experiments that use prisms to alter visual direction. However, prisms bias retinal flow patterns in ways that might affect the path chosen. We used a prism manipulation in virtual reality for g...

From the Euro-Mediterranean partnership to DG MENA: examining three decades of Euro-Mediterranean relations through the lenses of policy learning

Abstract This Special Issue examines the thirty-year trajectory of Euro-Mediterranean relations, through the lenses of policy learning. By analyzing what is learned, how learning occurs, and what outcomes emerge from the learning process, this Special Issue highlights how and to...