Research works

Mapping the adoption and implementation of artificial intelligence (AI)-based conversational interface for tobacco cessation: a scoping review protocol

Abstract Background Tobacco use remains a leading global public health issue, accounting for nearly 8 million deaths annually. Despite ongoing efforts through various health interventions and programmes aimed at tobacco cessation, significant challenges persist, particularly in l...

Perioperative tranexamic acid and postoperative haematuria after transvesical prostatectomy: a prospective observational cohort study

Bleeding and postoperative haematuria remain clinically relevant after open simple prostatectomy. Tranexamic acid (TXA) may reduce bleeding through antifibrinolytic activity, but evidence in open prostate surgery for benign prostatic obstruction is limited. This study evaluated p...

Social justice and mental health: nonlinear impacts of poverty and income inequality in Iran

Mental disorders are a major contributor to the global burden of disease, and poverty and income inequality are widely recognized as key social determinants of these conditions. In Iran, mental disorders rank as the second leading cause of disease burden. However, the association...

A Randomized Hybrid Type I Effectiveness-Implementation Study of an eHealth Delivery Alternative for Cancer Genetic Testing for Hereditary Cancer (eREACH2): study protocol

Abstract Background Germline cancer genetic testing has become a standard evidence-based practice, with established risk reduction and cancer screening guidelines for genetic carriers. There are also targeted treatments for some genetic carriers with cancers such as breast and ov...

Integrated remote sensing and observation methods to prioritise water well rehabilitation

Water shortage in arid and semi-arid regions has made groundwater the primary source of water supply. However, the performance of water wells gradually declines due to physical, chemical or biological clogging. Identifying wells with the highest rehabilitation potential is of sig...

It’s important, but...

Abstract In this article, we provide an analysis of discourses for and against the second language (L2) requirements on American university and college campuses. Facing enrollment declines in language programs, professional advocacy for L2 learning has shifted from liberal arts e...

Neurocognitive training with visual perturbation improves dual-task hop performance in male athletes after anterior cruciate ligament reconstruction: a randomized controlled trial

Returning to sport after anterior cruciate ligament reconstruction (ACLR) carries high re-injury risk and persistent functional impairments. Sensorimotor control changes not addressed by standard rehabilitation may lead to neurological compensations affecting functional performan...

Work with or work alone? How AI involvement in healthcare consultations shapes consumer responses to service failure

As artificial intelligence (AI) becomes increasingly integrated into healthcare services, an important question emerges: should AI be deployed to work with humans physicians' or autonomously to provide healthcare services? This research examines how varying levels of AI involveme...

A cyclic family arising from Larson's matroid counterexample: exact symmetric-exchange arity and a socle theorem

This record contains the mathematical note "A cyclic family arising from Larson's matroid counterexample: exact symmetric-exchange arity and a socle theorem" and a two-page theorem synopsis for quick reading. For a cyclic family M_m of rank-3m binary matroids, the note proves tha...

Protocol for the enrichment of endosteal and periosteal mesenchymal cells from murine bone for single-cell transcriptome analysis

Bone comprises diverse cell populations essential for skeletal development, remodeling, and homeostasis. Current single-cell isolation methods often use bulk digestion that can obscure distinctions between periosteal and endosteal compartments. Here, we present an optimized murin...

Tubular elements in lymph node metastases from lobular carcinomas with or without tubule formation

Invasive lobular carcinomas may demonstrate tubule formation both at the primary and at metastatic sites. A series of 135 invasive lobular carcinomas scrutinously screened for tubular elements were used, and tumours with axillary lymph node metastases were selected for review. Tw...

A Hybrid Grey Verhulst Modeling framework for accurate tea yield forecasting in variable environmental conditions

Purpose Due to the Ceylon tea industry having faced a range of economic, structural and climate conditions over the past few decades, a robust statistical approach is essential for short-term forecasting of tea yield and tea income. However, the existing literature indicates that...

Environmental and genetic interactions in autism spectrum disorder: a literature review with a focus on air pollution

Abstract Autism Spectrum Disorder (ASD) is a neurodevelopmental condition which is associated with complex interactions between genetic susceptibility and environmental exposures. More recently, air pollution has been investigated as a modifiable risk factor and contributor to th...

CT Perfusion in lacunar stroke: a powerful tool to enhance lacunar stroke detection and prediction of patients’ outcome

INTRODUCTION: Lacunar strokes are caused by occlusion of small penetrating arteries. Although CT perfusion (CTP) is widely used in the acute settings, automated core/penumbra software often fails to detect lacunar perfusion abnormalities, so its diagnostic and prognostic roles re...

Esketamine induces ferroptosis and suppresses immune evasion in lung adenocarcinoma cells via the hsa_circ_0022392/miR-548b-3p/MAP7 axis

Abstract Background Although Esketamine, an N-methyl-D-aspartate (NMDA) receptor antagonist, is widely used for anesthesia and analgesia and has shown anticancer activity, its effects on lung adenocarcinoma remain unclear. Circular RNAs have been implicated in the development and...

A Multi-omics Regulated Cell Death Framework Defines Immune Phenotypes and Guides Precision Therapy in Colorectal Cancer

Colorectal cancer (CRC) is molecularly and immunologically heterogeneous, contributing to variable treatment response. Because regulated cell death (RCD) intersects with tumor metabolism, immune regulation, and therapeutic susceptibility, we built an RCD-centered framework for CR...

Nutritional support for critically ill patients by the Korean Society for Parenteral and Enteral Nutrition—part II: a clinical practice guideline

Purpose: Nutritional therapy is an essential component of intensive care management. Appropriate nutritional support may reduce infectious and metabolic complications and promote recovery in critically ill patients. However, nutritional practices vary across institutions, and int...

Global Observables in Statistical Mechanics

Abstract We present a canonical construction of global observables -sometimes referred to in the literature as macroscopic observables or observables at infinity- in statistical mechanics, providing a unified treatment of both commutative and non-commutative cases. Unlike standar...

Chemical Features of Rare-Earths Accessory Minerals in the Lower–Middle Cambrian Terrigenous Rocks from the Argun Series of the Northwestern Part of the Argun Superterrane as Indicators of the Sources

Abstract The paper presents the results of the chemical study of rare-earth accessory minerals of the Lower–Middle Cambrian terrigenous rocks of the Bystraya Formation and the Ernichny Unit of the Argun Series of the Argun Superterrane. The chemical analysis of monazite, xenotime...

Aum Shinrikyo and the AI Uplift Problem: How LLMs Could Lower the Threshold for CBRN Harm

This case study examines how large language models could lower the barriers to chemical, biological, radiological, nuclear, and explosives harm by improving access to technical knowledge, troubleshooting, interpretation, and operational decision-making. Using Aum Shinrikyo as a h...