Research works
The research papers we track — the newest first. Works with a plain-language summary link to it.
138309 work(s)
- BiologyOpen access
Large transgene arrays cause aberrant transcription and synthetic molting defects
Abstract Multicopy transgene arrays remain widely used in Caenorhabditis elegans research. It is usually assumed that they behave neutrally, not impacting the phenotype under investigation. Here, we reveal that a previously reported heterochronic extra-molt phenotype associated w...
- Engineering & TechnologyOpen access
Ultra-dense networking (UDN) in air–ground integrated Internet of Vehicles (IoV) networks promises substantial gains in network capacity. However, the mobility of both unmanned aerial vehicle (UAV) base stations and ground vehicles makes handovers increasingly frequent and drives...
- Engineering & TechnologyOpen access
Accurate alignment of large-scale components in manufacturing systems is often achieved by inserting locating pins into mating faces. In such operations, each locating pin must sequentially pass through two non-coaxial holes with a clearance of less than 50 μm, a requirement that...
- Health & MedicineOpen access
Combining TAG ‐ 72CAR with anti‐ MUC16CAR improves the potency of ovarian cancer treatment
Ovarian cancer (OC) is typically associated with poor prognosis and high mortality. Chimeric antigen receptor (CAR) T‐cell therapy offers a promising strategy, yet its application in solid tumours remains constrained by limited efficacy and on‐target/off‐tumour toxicities. We pre...
- Materials & Energy
Abstract We report the development of synthetic routes to representative Bauhinia family natural products, including pacharin, bauhiniastatins 1–4, and bauhinoxepins C–J. The key transformation involves a one-pot aldol condensation/SNAr sequence to efficiently construct the diben...
- BiologyOpen access
Abstract Introduction Nicotine, a addictive substance in tobacco products, has profound negative impacts on oral and systemic health. This study aims to investigate salivary metabolites and metabolic pathways in nicotine pouch users. Methods This study included 28 participants. O...
- Society & EconomicsOpen access
BOTTOM LESS AGAM KUAN IS SELF-EXPLANATORY ARCHAEOLOGICAL SYMBOL OF CRUELTY
The "fathomless well" of Patna is famously known as Agam Kuan. Located near the Gulzarbagh railway station in Patna, Bihar, its name literally translates to "unfathomable well". It is one of the most important and mystery-shrouded archaeological sites in Patna, dating back to the...
- Engineering & TechnologyOpen access
Impact of control augmentation on pilot workload during shipboard helicopter hover operation
Abstract The integration of control augmentation techniques into helicopter systems aims to assist pilots during the critical phases of shipboard operations to mitigate the effects of ship motion, wind and other environmental factors that can compromise safety. The control augmen...
- Health & MedicineOpen access
Abstract Background Artificial intelligence (AI) is increasingly integrated into higher education, including medical education, particularly for research training and academic writing. Research methodology and biostatistics courses are often perceived as challenging, with student...
- Climate & EnvironmentOpen access
Microplastics (MPs) in agroecosystems displayed phytotoxicity; however, the differential effects of pristine and photoaged MPs remain unclear. Herein, we examined the effects and mechanisms of polystyrene (PS) MPs on wheat ( Triticum aestivum L .) based on pristine and photoaged...
- BiologyOpen access
Honey is valued for its nutritional and health-promoting properties; however, its quality depends not only on the presence of bioactive compounds but also whether it is contaminated with toxic elements and pesticide residues. Although organic beekeeping is intended to reduce chem...
- BiologyOpen access
Webinar on the METROFOOD.BE story
This webinar presents the main results and progress of METROFOOD.BE and the METROFOOD-FED.BE project. It highlights how Belgian expertise, services and infrastructure contribute to METROFOOD-RI and support metrology in food and nutrition.
- Health & MedicineOpen access
Abstract Cryptococcus neoformans and Cryptococcus gattii are environmental fungi that cause cryptococcosis, a severe, life-threatening infection, particularly in immunocompromised individuals. Current treatments are limited by toxicity, restricted availability, and the emergence...
- Health & MedicineOpen access
Information on Leptospira spp. exposure in Mexican equids remains limited. This cross-sectional study evaluated seropositivity and antigen-specific seroreactivity in 313 apparently healthy equids enrolled by convenience sampling in Los Tuxtlas (n = 119), Sotavento (n = 108), and...
- Engineering & TechnologyOpen access
Urban rail passenger flow forecasting, based on large-scale automatic fare collection (AFC) sensor networks, is typically evaluated on ordinary days, yet operators most need accurate predictions during event days. The AFC infrastructure comprises 191 sensor-equipped stations with...
- Physics & SpaceOpen access
This work introduces the Finsler-Mucini formalism, a novel cosmological framework where spacetime geometry is extended from the purely positional Riemannian manifold to the tangent bundle TM, incorporating kinetic velocity, quantum frequencies, and local temperature. By introduci...
- Health & MedicineOpen access
Background & Objective: Advanced endometriosis is recognized as a potential cause of Diminished Ovarian Reserve (DOR), yet data on its prevalence, predictors, and patient awareness in Central Asia are scarce. The present study was conducted with aim to determine the prevalence of...
- BiologyOpen access
Tigecycline is considered a last-resort antibiotic against multidrug-resistant Gram-negative bacteria. The emergence of the mobile resistance gene tet (X4), which confers high-level resistance to tigecycline, has raised growing concern due to its rapid dissemination among humans,...
- BiologyOpen access
Mitochondrial quality control is essential for maintaining neuronal function during aging. Nipsnap1 (Nip1), a mitochondrial protein involved in mitophagy, metabolic regulation, and cellular senescence, has emerged as a potential regulator of tissue homeostasis; however, its role...
- Society & EconomicsOpen access
Insomnia symptoms are common during the menopausal transition, but estrogen-centered explanations do not fully account for inter-individual variation. We examined whether serum prolactin was associated with insomnia severity and whether circulating basic amino acids modified this...