Research works

The Effects of Street Cleaning on Serious Crime and Gun Violence in Philadelphia, 2023-2024: A Stratified Randomized Controlled Trial.

. 2026;116(8):1171-1179. https://doi.org/10.2105/AJPH.2026.308429).

Understanding College Student Expectancies of Simultaneous Engagement in Multiple Risk Behaviors: A Measurement Development and Model Testing Study

Risky behaviors, actions that may cause physical, psychological, social, or economic harm to oneself or others, are prevalent among college students. While significant research has focused on single high-risk behaviors of alcohol use, drug use, gambling, and gaming separately, st...

Risk of type 2 diabetes mellitus after treatment with direct-acting antivirals for Hepatitis C virus in people with HIV.

Objective To compare the 3-year risk of type 2 diabetes mellitus (T2DM) in people with HIV-HCV after direct-acting antiviral (DAA) initiation and in people with HIV mono-infection.Design An observational study of two collaborations of cohorts from Europe and North America.Methods...

Approach and nomenclature problems of extracutaneous basaloid neoplasias of visceral organs with three cases of basaloid carcinoma described for the first time in the urinary bladder.

Pure basal cell carcinomas/basaloid carcinomas (BCC/BC) from only basal cells in the urinary bladder have not been reported so far. Our aim in this study was to present three BC cases showing distinct pilomatrixoma-like keratinization (matrixial) and sebaceous differentiation in...

Epidemic Belfast: Health Heritage, Public History and Inclusivity in Northern Ireland

Since 2021, the Epidemic Belfast project has developed innovative ways of researching and communicating health history, with regional and international audiences. This article reviews the project’s development while offering insight into best practice for curating health history...

Performance Evaluation of Si Power and SiC MOSFET, IGBT, and HEMT GaN at Cryogenic Temperature for Superconducting Propulsion System

International audience

Application of the ultrasonic oscillation flotation method in paraffin section preparation.

OBJECTIVE: To enhance the quality and efficiency of paraffin-embedded pathological section preparation, this study aims to investigate the potential benefits of utilizing the ultrasound oscillation flotation method (UOFM) for section spreading. METHODS: Specimens of various tissu...

Nicotinamide adenine dinucleotide phosphate hydrogen oxidase 2 exacerbates abdominal aortic aneurysm formation by inducing oxidative stress through autophagy inhibition.

, primary mouse vascular smooth muscle cells (VSMCs) were randomly divided into Control, AngII, AngII+GSK2795039, AngII+rapamycin (autophagy agonist, RA), and AngII+GSK2795039+RA groups. EDU assay, cell scratch assay, and mRFP-GFP-LC3 detection were conducted. ROS was measured by...

Immunohistological parathormone production changes and angiogenesis in normal and adenomatous human parathyroid glands.

INTRODUCTION: Parathyroid tumor function is not always positively correlated with tumor size, complicating the disease picture. Here, we compared parathormone (PTH) and vascular endothelial growth factor (VEGF)-A expression intensities in normal and adenomatous parathyroid glands...

Real-time railhead friction estimation using machine learning: development of an on-board-train data capture system

Low adhesion between the wheel and rail interface remains a significant challenge for the railway industry, particularly during the autumn season, leading to delays and safety risks such as station overruns and signals passed at danger (SPADs). The impact of low adhesion is estim...

Prognostic significance of ACADL and MCM2 in meningiomas: Current evidence and clinical implications.

-wildtype, hypermetabolic, and proliferative. The latter two groups have the worst clinical outcomes and are enriched in ACADL and MCM2 expression, suggesting their potential as immunohistochemical surrogates. The revision of the current literature on the expression of these mark...

Fast Field Mapping of Large Size Bulk Superconductors at Variable Temperatures and Magnetic Fields

The authors thank Carnot ICEEL and the CAPMAT project (co-funded by FEDER-FSE Lorraine et Massif des Vosges 2014-2020) for their support and acknowledge Quentin Nouailhetas (now at Tokamak Energy, UK) for helping in the design of the sample holder.

Aldose reductase as a regulator of ocular pathology: Mechanisms and therapeutic potential.

Aldose reductase (AR), the rate-limiting enzyme of the polyol pathway, converts glucose to sorbitol using NADPH and becomes markedly overactive under hyperglycemic conditions. Its widespread expression in ocular tissues links AR to numerous eye disorders through sorbitol accumula...

Squamous papilloma of the external ear in Southwest China: A large case series highlighting predominant HPV subtypes, pathologic features, and unique epidemiologic factors.

Squamous papilloma (SP) of the external ear is a rare benign neoplasm, with limited research on its associated human papillomavirus (HPV) infections and pathologic features. This study aims to provide a comprehensive analysis of the largest case series of external ear SP from Sou...

CD34+ cells contribute to cardiac remodeling during disease development.

cell enrichment toward lineage-specific therapeutic strategies.

Clinical-histological and genetic features of rare variants of melanoma.

Melanoma is traditionally classified into a limited number of common clinicopathologic subtypes; however, routine clinical and histopathologic practice reveals a broad spectrum of rare variants and unusual morphologic patterns that pose significant diagnostic and therapeutic chal...

LLM-based early rumor detection with imitation agent

Early Rumor Detection (EARD) aims to identify the earliest point at which a claim can be accurately classified based on a sequence of social media posts. This is especially challenging in data-scarce settings. While Large Language Models (LLMs) perform well in few-shot NLP tasks,...

Naoluotong granules inhibit necroptosis of neural cells and improve cerebral ischemia-reperfusion injury by regulating the RIP1/NIK/IKKα/NF-κB pathway.

BACKGROUND: Cerebral ischemia-reperfusion can cause structural changes in brain tissue and disrupt physiological functions. Naoluotong granules (NLT) exhibit significant neuroprotective effects on brain nerve cells and are widely utilized in treating cerebral ischemia-reperfusion...

Experimental full-field investigation of stress development in austenite during the thermally-activated transformation of a Cu-Al-Ni single crystal

The paper presents an experimental analysis of the stress field developing within austenite in a Cu-Al-Ni single crystal during its thermally-activated transformation to martensite. Starting from a virgin sample in austenitic state, fifty homogeneous cooling-heating cycles allowe...

Astragalus polysaccharide protects against neuron degeneration and mitochondrial dysfunction in Parkinson's disease by upregulating CEND1.

BACKGROUND: possesses antioxidant, anti-inflammatory, and neuroprotective properties. APS was previously revealed to exert neuroprotective effects in experimental PD models. However, the underlying mechanism remains poorly understood. Therefore, our study was designed to reveal t...