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SAMHITA PRINCIPLES IN THE MANAGEMENT OF DISEASES: AN AYURVEDIC REVIEW

Ayurveda, the traditional system of medicine of India, has made a significant contribution to healthcare since ancient times and continues to gain worldwide recognition. Among its fundamental concepts, Samhita Siddhanta forms the cornerstone of understanding the etiology, pathoge...

STABILITY-INDICATING HPTLC METHOD DEVELOPMENT AND VALIDATION FOR SIMULTANEOUS ESTIMATION OF GABAPENTIN AND NORTRIPTYLINE IN BULK DRUG AND MARKETED FORMULATION

Gabapentin and nortriptyline are co-formulated (100 mg/10 mg and 200 mg/10 mg strengths) and used for the management of neuropathic pain, yet no stability-indicating high-performance thin-layer chromatographic (HPTLC) method for their simultaneous estimation has been reported to...

ARTIFICIAL INTELLIGENCE IN HIGH-PERFORMANCE LIQUID CHROMATOGRAPHY: TRANSFORMING METHOD DEVELOPMENT, OPTIMIZATION, AND DATA ANALYSIS- A COMPREHENSIVE REVIEW

High-Performance Liquid Chromatography (HPLC) is a critical analytical technique for separating, identifying, and quantifying compounds, but traditional gradient method development is resource-intensive and time-consuming. This review explores the integration of artificial intell...

IN VIVO EVALUATION OF THE ANTI-ALZHEIMER'S POTENTIAL OF THE ETHANOLIC EXTRACT OF ARTOCARPUS HETEROPHYLLUS SEEDS IN SCOPALAMINE- INDUCED MALE ALBINO RATS

Alzheimer's disease (AD) is a chronic, progressive neurodegenerative disorder and the leading cause of dementia worldwide. It is characterized by progressive deterioration of memory, cognition, language, executive function, and behavior, ultimately affecting activities of daily l...

IMPACT OF HEADPHONES AND IN-EARBUDS ON HEARING PERCEPTION AND KARNANADA (TINNITUS) AMONG YOUNG ADULTS: AN OBSERVATIONAL CROSS-SECTIONAL STUDY

Background: The widespread adoption of personal audio devices (PADs), particularly headphones and in-earbuds, has increased the risk of recreational noise-induced hearing loss (NIHL) and tinnitus among young adults. Ayurveda describes similar auditory manifestations under Karnana...

PREVALENCE OF TINEA AMONG PATIENTS ATTENDING DERMATOLOGY CONSULTATION UNITS IN MOSUL CITY

Dermatophyte infections (tinea) are common superficial fungal infections of the skin, hair, and nails that constitute a substantial public health burden, particularly in developing countries. This cross-sectional study aimed to determine the prevalence, demographic distribution,...

AN AYURVEDIC APPROACH IN THE MANAGEMENT OF VIPADIKA (PALMOPLANTAR PSORIASIS) - A CASE REPORT

Palmo-plantar psoriasis is a non-infectious chronic inflammatory dermatological condition that predominantly affects the palms and soles and is capable of producing significant functional disability. It is characterized by erythema, scaling, itching, fissuring, pustule formation,...

INDIVIDUALIZED AYURVEDIC MANAGEMENT RESULTING IN NATURAL CONCEPTION AFTER REPEATED FAILED ASSISTED REPRODUCTIVE TECHNOLOGY CYCLES: A CASE REPORT

Background: Infertility is a multifactorial condition that can significantly affect the emotional, psychological, and social well-being of couples. Repeated failures of assisted reproductive techniques such as intrauterine insemination (IUI) and in vitro fertilization (IVF) often...

ANALYTICAL METHOD DEVELOPMENT AND VALIDATION OF RP-HPLC METHOD FOR ESTIMATION OF IMEGLIMIN IN BULK AND PHARMACEUTICAL DOSAGE FORM

Imeglimin Hydrochloride is a novel anti-diabetic drug used in the management of Type 2 Diabetes Mellitus. The present study focuses on the development and validation of a simple, precise, accurate, and economical Reverse Phase High-Performance Liquid Chromatography (RP-HPLC) meth...

AYURVEDIC MANAGEMENT OF ANIDRA (INSOMNIA) WITH NIDRAKAR CHURNA AND KSHEERBALA TAILA SHIROPICHU: A CASE REPORT

Background: Insomnia is a common neuropsychological disorder affecting emotional stability, cognitive performance, and autonomic balance. Contemporary pharmacological therapies often provide temporary relief but may be associated with tolerance, residual sedation, cognitive impai...

PERIOPERATIVE AIRWAY EDEMA DUE TO PROLONGED TRENDELENBURG POSITION

Airway edema is an uncommon but potentially life-threatening complication following prolonged surgery in the Trendelenburg position, particularly during laparoscopic pelvic procedures. Early recognition and appropriate airway assessment are essential to prevent post-extubation ai...

DESIGN, DEVELOPMENT, AND EVALUATION OF A POLYHERBAL FORMULATION FOR THE MANAGEMENT OF METABOLIC SYNDROME

Metabolic syndrome (MetS) represents a clustering of interconnected risk factors including central obesity, insulin resistance, dyslipidemia, and hypertension, which collectively increase the risk of type 2 diabetes mellitus and cardiovascular disease. The limitations of conventi...

SYNTHESIS, SPECTRAL CHARACTERIZATION AND IN VITRO ANTIMALARIAL EVALUATION OF NOVEL QUINOLINE-BASED THIAZOLIDIN-4-ONE DERIVATIVES

A series of novel quinoline-based thiazolidin-4-one derivatives were synthesized through a three-step synthetic pathway involving nucleophilic substitution, Schiff base formation and cyclization reactions. Initially, 4-chloroquinoline was converted into 4-hydrazinylquinoline by r...

LAKHLAKHA (OLFACTION THERAPY) FOR THE MANAGEMENT OF CHRONIC INSOMNIA: A CASE REPORT

Background: Insomnia is a prevalent sleep disorder causing significant daytime impairment and reduced quality of life. Conventional pharmacotherapies often present risks of side effects, tolerance, and dependence, highlighting the need for complementary options. In Unani medicine...

AN AYURVEDIC APPROACH IN THE MANAGEMENT OF VIPADIKA (PALMOPLANTAR PSORIASIS) - A CASE REPORT

Palmo-plantar psoriasis is a non-infectious chronic inflammatory dermatological condition that predominantly affects the palms and soles and is capable of producing significant functional disability. It is characterized by erythema, scaling, itching, fissuring, pustule formation,...

KARNA SRAV (OTORRHEA): AN INTEGRATIVE AYURVEDIC AND MODERN PERSPECTIVE

Karna Srav, described under Karna Roga in Ayurveda, refers to abnormal ear discharge and is considered a symptom rather than an independent disease.[12] It closely correlates with Otorrhea in modern medicine, commonly caused by infection, trauma, or tympanic membrane perforation....

CLINICAL MANAGEMENT OF VATAPRAKOPA-JANYA GRIDHRASI (SCIATICA) VIA TARGETED SIRAVEDH (VENEPUNCTURE) AND SUPPORTIVE ORAL COMPLEMENTARY FORMULATIONS: A CARE-COMPLIANT CASE REPORT

Background: Gridhrasi is a major musculoskeletal disorder categorized under the eighty Nanatmaja Vatavyadhis in Ayurveda. It closely resembles the modern clinical entity of Sciatica, typically caused by lumbar intervertebral disc herniation, canal stenosis, or nerve root compress...

STUDY OF BIOTRANSFORMATION OF MEFENAMIC ACID AND BIOMOLECULES AND ADR (ADVERSE DRUG REACTION) MONITORING OF RELATED DRUGS

Mefenamic acid is a widely prescribed non-steroidal anti-inflammatory drug (NSAID) that is commonly used for the management of pain, inflammation, fever, dysmenorrhea, and various musculoskeletal disorders. Despite its clinical effectiveness, prolonged or inappropriate use of mef...

PHYSICOCHEMICAL EVALUATION AND HPTLC FINGERPRINTING OF VIPAREETA MALLA TAILA AND ITS OINTMENT FORMULATION

Background: Vipareeta Malla Taila, a classical Ayurvedic oil-based formulation described in Chakradatta under Vrana Shotha Adhikara, is traditionally indicated for the management of Vrana. Modification of traditional dosage forms into patient-friendly formulations, such as ointme...

ARKAKSHIR SHAKHADRAVA EMBEDDED KSHARSUTRA IN THE MANAGEMENT OF MASHAK (MOLE): A CASE SERIES

Background: Mashak (mole/melanocytic nevus) is a benign pigmented skin lesion described in Ayurvedic classics under Kshudra Rogas. Although mostly harmless, moles can cause cosmetic concerns or rarely undergo malignant transformation. Conventional treatments include surgical exci...