Research works

COMPARATIVE SCREENING OF HEAVY METAL-TOLERANT MICROORGANISMS FOR SUSTAINABLE ENVIRONMENTAL BIOREMEDIATION

Heavy metal contamination is a major environmental concern due to its toxic effects on living organisms and long-term persistence in the environment. The present study evaluated the tolerance and antimicrobial activity of four heavy metals-cadmium chloride, potassium dichromate,...

TRANSITION FROM PORTOPULMONARY HYPERTENSION TO HEPATOPULMONARY SYNDROME IN A PATIENT WITH CIRRHOSIS: A RARE CLINICAL EVOLUTION

Porto-pulmonary hypertension (POPH) and hepatopulmonary syndrome (HPS) are distinct pulmonary vascular complications of chronic liver disease and portal hypertension. Despite sharing a common underlying hepatic pathology, they are characterized by opposing pathophysiological mech...

A COMPARATIVE STUDY FOR THE EVALUATION OF FOUR DIFFERENT BRANDS OF ORAL ANTI DIABETIC DRUG "GLIMEPIRIDE 1 MG"

The objective of this research work was to formulate and comprehensively evaluate glimepiride tablets utilizing the uncoated tablets. Tablets represent the most widely prescribed solid oral dosage form owing to their dosing accuracy, physical stability, and ease of manufacturing....

FORMULATION AND EVALUATION OF MATRIX TYPE TRANSDERMAL PATCH OF DICLOFENAC SODIUM

Background: The clinical and biopharmaceutical utility of oral Diclofenac Sodium is severely constrained by its exceptionally short biological half-life (1.2 to 2.0 hours) and a high incidence of gastrointestinal systemic complications, including mucosal ulceration, localized ble...

NEUROBEHAVIORAL PROTECTIVE EFFECTS OF POTASSIUM IODIDE AGAINST POTASSIUM BROMIDE-INDUCED NEUROTOXICITY IN MICE

Background: Potassium bromide (KBr) has long been used as an anticonvulsant agent; however, prolonged exposure may induce neurobehavioral disturbances associated with central nervous system depression. Potassium iodide (KI) is an essential iodine source required for normal neurol...

PRAMANA SHARIR: THE TRADITIONAL AYURVEDIC METHOD OF BODY MEASUREMENT AND ITS RELEVANCE ACROSS VARIOUS FIELDS OF AYURVEDA

Anthropometry is the systematic and quantitative study of the human body and its physical dimensions. Derived from the Latin terms anthropos (human) and metry (measurement), it involves the measurement of body size, shape, and composition, including skeletal, muscular, and adipos...

A CRITICAL REVIEW ON AYURVEDIC CUISINE: BRIDGING ANCIENT CULINARY SCIENCE WITH MODERN NUTRITION, THERAPEUTICS AND BIOECONOMY

Ayurvedic cuisine is a holistic dietary system that integrates nutrition, culinary practices, and therapeutics to promote health, prevent disease, and maintain physiological balance. Classical Ayurvedic texts regard Ahara (diet) as one of the Trayopastambha (three sub pillars of...

ASSESSMENT OF KNOWLEDGE, ATTITUDE, AND PRACTICE OF EMERGENCY CONTRACEPTION AMONG FEMALE STUDENTS OF FEDERAL COLLEGE OF EDUCATION (TECHNICAL), GOMBE, NIGERIA

Background: Emergency contraception (EC) is an important option for preventing unintended pregnancies. Despite its proven effectiveness, awareness, knowledge, and actual use among young women in Nigeria remain suboptimal. This study evaluated the knowledge, attitudes, and practic...

AYURVEDIC MANAGEMENT OF KRIMIGRANTHI (SEBORRHEIC BLEPHARITIS): A CASE REPORT

Krimigranthi, described in Ayurveda as a Kapha-pradhana, Bhedana-sadhya, Sandhigata Netra Roga, can be correlated with chronic (seborrheic) blepharitis, a common eyelid disorder frequently encountered in ophthalmology practice. Classical management of Krimigranthi includes Swedan...

FORMULATION AND EVALUATION OF MANTELUKAST SODIUM CHEWABLE TABLET

Montelukast sodium is a selective leukotriene receptor antagonist widely used for the prophylaxis and chronic management of asthma and allergic rhinitis. The present study aimed to formulate and evaluate Montelukast sodium tablets with improved tablet performance, rapid drug rele...

FORMULATION AND CHARACTERIZATION OF HERBAL ANTI-AGING CREAM ENRICHED WITH CAMPHOR AND SEA BUCKTHORN OIL

Skin aging is a natural biological process influenced by intrinsic and extrinsic factors such as ultraviolet radiation, oxidative stress, environmental pollution, and lifestyle. These factors lead to collagen degradation, reduced skin elasticity, wrinkle formation, and dryness. H...

AN INTERESTING CASE OF ACUTE FLACCID PARALYSIS: A DIAGNOSTIC CHALLENGE

Acute Flaccid Paralysis (AFP) is a complex, neurological clinical syndrome characterized by the rapid onset of profound muscle weakness, hypotonia, and diminished or absent deep tendon reflexes. The progression of weakness can be aggressive, occasionally leading to devastating co...

YUKTI TO NANO-PHARMACOLOGY: UNDERSTANDING ALPAMATRA MAHARTHATVAM AND THE THERAPEUTIC POTENTIAL OF RASAUSHADHIS

Background: Rasaushadhis represent a unique class of herbo-mineral formulations in Ayurveda, distinguished by three remarkable characteristics: administration in minute doses (Alpamatra), rapid therapeutic action (Kṣipramarogyadayitvat), and patient palatability (Arucheraprasanga...

फलसव WSR To KAJAVASAVA IN KAPHAJA KASA PHALASAVA: WSR To KAJAVASAVA IN KAPHAJA KASA

Kaphaja Kasa is a common respiratory disorder described in Ayurveda, primarily caused by the vitiation of Kapha Dosha, leading to symptoms such as productive cough with thick, white or Pandu-coloured sputum, heaviness, and chest congestion. The management of Kaphaja Kasa focuses...

PRECISION THERAPEUTICS IN PRIMARY IMMUNE REGULATORY DISORDERS: CURRENT ADVANCES AND FUTURE DIRECTIONS

Primary immune regulatory disorders (PIRDs) are a heterogeneous group of inborn errors of immunity characterized by impairment of immune tolerance and homeostasis leading to autoimmune, autoinflammatory, lymphoproliferative diseases and recurrent infections. Recent developments i...

ASSOCIATION OF ANTIBIOTIC RESISTANCES AMONG MYCOBACTERIUM TUBERCULOSIS AMONG SALAH-ALDEEN COMMUNITY

Background: Mycobacterium tuberculosis, the etiological agent causing tuberculosis, is one of the most common contagious diseases that poses a serious threat to human health. As per the recent WHO report, TB incidence throughout the world amounts to 10.7 million and the total dea...

PREVALENCE OF TINEA AMONG PATIENTS ATTENDING DERMATOLOGY CONSULTATION UNITS IN MOSUL CITY

Dermatophyte infections (tinea) are common superficial fungal infections of the skin, hair, and nails that constitute a substantial public health burden, particularly in developing countries. This cross-sectional study aimed to determine the prevalence, demographic distribution,...

MANAGEMENT OF INDRALUPTA (DRUG INDUCED ALOPECIA)- A CASE STUDY

Introduction: Indralupta falls under one of the Urdhwajatrugata Vyadhi characterized by the patchy hair loss over hair-bearing skin that includes scalp and beard. According to the Acharya Sushruta, Indralupta is due to the vitiated pitta in association with vitiated Vata causing...

SUCCESSFUL PREGNANCY FOLLOWING INTEGRATIVE AYURVEDIC MANAGEMENT IN A WOMAN WITH UNILATERAL TUBAL BLOCKAGE, HYPERTHYROIDISM, POOR OVARIAN RESERVE, AND PREVIOUS ECTOPIC PREGNANCY: A CASE REPORT

Background: Tubal factor infertility accounts for approximately 25–35% of female infertility. Women with unilateral salpingectomy following ectopic pregnancy and contralateral tubal blockage have limited options for natural conception and are frequently advised assisted reproduct...

DEVELOPMENT AND EVALUATION OF FINASTERIDE NANO-SUSPENSIONBASED TOPICAL DELIVERY FOR ENHANCED THERAPEUTIC EFFICACY

Finasteride is an effective 5α-reductase inhibitor used in the management of androgen-dependent hair disorders; however, oral administration is associated with systemic adverse effects and limited patient compliance. The present study aimed to develop and evaluate a finasteride n...