Research works

Multifeature sequencing-based liquid biopsy for cancer diagnosis and monitoring

Abstract Liquid biopsy has emerged as a transformative development in oncology, enabling the minimally invasive detection and monitoring of cancer through the analysis of tumor-derived material in blood. Moving beyond single-variable analysis, multifeature sequencing-based liquid...

GLOBAL EINSTEIN -AND- VAN CONG RELATIONS, AND NEW OPTICAL-ELECRICAL-THERMOELECTRIC LAWS IN N(P)-TYPE DEGENERATE, COMPENSATED AND VISCOUS CdS(1-x)Se(x)-CRYSTALLINE ALLOY, ENHANCED BY OUR STATIC DIELECTRIC CONSTANT LAW, CONDUCTIVITY MODEL, AND ESPECIALLY ACCURATE FERMI ENERGY EXPRESSION (49)

In degenerate, compensated and viscous - crystalline alloy, , the Global Einstein -and- Van Cong relations, as those given in Equations (24, 31), and various optical-electrical-thermoelectric laws, enhanced by: the optico-electrical phenomenon (O-EP) and the electro-optical pheno...

UNDERSTANDING THE MECHANISM OF VAMANA KARMA THROUGH CLASSICAL PRINCIPLES AND MODERN EMESIS PHYSIOLOGY

Background: Vamana Karma, one of the principal purification procedures of Panchakarma, is indicated predominantly in Kapha-dominant disorders and aims at expelling vitiated doshas through therapeutic emesis. Although its clinical utility is widely acknowledged in Ayurvedic practi...

No Test, No Claim: Untested Code Is Vibed Code

When a large language model writes code we do not trust, we tend to blame the author: a machine wrote it, so it must be suspect. This paper argues that the instinct points at the wrong variable. What makes code trustworthy is not who wrote it but whether reproducible evidence exi...

KSHARA SUTRA IN THE MANAGEMENT OF INTERSPHINCTERIC BHAGANDARA (PERIANAL FISTULA-IN-ANO): A CASE REPORT

Bhagandara (fistula-in-ano) is regarded by Acharya Sushruta as difficult to manage, owing to its chronic, recurrent, discharging nature. Kshara Sutra, a medicated thread prepared with Snuhi Ksheera, Apamarga Kshara and Haridra churna, combines Kshara Karma (chemical cauterisation...

GLOBAL EINSTEIN -AND- VAN CONG RELATIONS, AND NEW OPTICAL-ELECRICAL-THERMOELECTRIC LAWS IN N(P)-TYPE DEGENERATE, COMPENSATED AND VISCOUS CdTe(1-x)S(x)-CRYSTALLINE ALLOY, ENHANCED BY OUR STATIC DIELECTRIC CONSTANT LAW, CONDUCTIVITY MODEL, AND ESPECIALLY ACCURATE FERMI ENERGY EXPRESSION (46)

In degenerate, compensated and viscous - crystalline alloy, , the Global Einstein -and- Van Cong relations, as those given in Equations (24, 31), and various optical-electrical-thermoelectric laws, enhanced by: the optico-electrical phenomenon (O-EP) and the electro-optical pheno...

SELM-CTR: a stacking ensemble deep learning model with SHAP-based analysis for large-scale click-through rate prediction

Purpose Click-through rate (CTR) prediction is a core challenge in digital advertising, as forecasting whether a user will click on an advertisement directly determines ad placement decisions and revenue outcomes. Standard machine learning and deep learning approaches achieve rea...

Centering Veteran expertise: advancing peer-led harm reduction in the Veterans health administration

Abstract The principle “Nothing about us without us” underscores the ethical imperative to involve people with lived and living expertise in shaping harm reduction praxis. While the United States Veterans Health Administration (VHA) has expanded harm reduction initiatives, such a...

Reflection Activity After Patient Death to Reduce Anxiety in Intensive Care Nurses

BACKGROUND: Many nurses, particularly those working in intensive care units, experience anxiety and burnout as a result of caring for patients with complex conditions and high mortality rates. This situation often leads to employee dissatisfaction and high turnover. LOCAL PROBLEM...

Cost-effectiveness of screening for developmental dysplasia of the hip in children born in England and Wales

Aims: The aim of this study was to evaluate the cost-effectiveness of screening programmes for identifying developmental hip dysplasia (DDH) in children born in England and Wales. Methods: The costs and quality-adjusted life-years (QALYs) associated with DDH screening programmes...

The LLM Commoditization Playbook: How Enterprises Exploit Price Competition Between Providers

Research article: The LLM Commoditization Playbook: How Enterprises Exploit Price Competition Between Providers

Study on Bifidobacterium breve B2798 in obese mice

Bifidobacterium breve B2798 ameliorates high-fat diet-induced obesity by reshaping gut microbiota and modulating host metabolic profiles

A critical review of the early clozapine trials published in German and a discussion of the many unresolved issues left by these trials

Clozapine was (1) first introduced in Austria and Switzerland in 1972, (2) associated with 8 Finnish deaths due to agranulocytosis in 1975 (almost leading to its withdrawal), and (3) approved in the United States (US) for treatment-resistant schizophrenia in 1989 (resulting in a...

Simulation-based ultrasound-guided lumbar puncture training using a flipped classroom: a single-arm pilot programme evaluation

Abstract Background Traditional landmark-guided lumbar puncture (LP) has high failure rates among novice emergency medicine (EM) clinicians. While ultrasound guidance improves success, structured training models remain limited and expensive. We evaluated a cost-effective, simulat...

Washout characteristics of sevoflurane and desflurane in surgical patients: a prospective observational study using gas chromatography - ion mobility spectrometry

Abstract Background Sevoflurane and desflurane are routinely used volatile anaesthetics in balanced general anaesthesia, but their elimination time from the human body may be underestimated. Methods Levels of sevoflurane and desflurane in end-tidal exhaled breath and ambient room...

ASSESSMENT OF THE ANTI-INFLAMMATORY ACTIVITY OF SIDDHARTHAKADI AGAD BY AN IN VITRO METHOD

Inflammation is a protective physiological response against harmful stimuli such as infection, injury, and toxins; however, chronic inflammation may lead to tissue damage and various pathological conditions. Siddharthakadi Agad, a classical polyherbal formulation described in Cha...

Flood-induced displacement and resilience: the mediating role of coping strategies within the sustainable livelihood framework

Abstract Flood-induced displacement has become a critical challenge in disaster-prone areas particularly in low-income countries where communities depend entirely on the natural resources. This study examines how various forms of livelihood capital such as natural, physical, huma...

ASSESSMENT OF PREGNANT WOMEN'S KNOWLEDGE AND PRACTICES REGARDING ANTENATAL CARE AT AL-QUDIS PRIMARY HEALTH CARE CENTER, MOSUL CITY

Background: Antenatal care is an essential component of maternal healthcare that aims to promote the health of both the mother and fetus through early detection and management of pregnancy-related conditions, health education, and preventive interventions. Pregnant women's knowle...

INVESTIGATION OF THE RESVERATROL EFFECT ON IL-6 RECEPTOR GENE EXPRESSION LEVEL IN ACUTE MYELOID LEUKEMIA CELL

Resveratrol has been extensively investigated as a natural compound with promoising anticancer properties. the present study evaluated whether resveratrol modulates IL-6R gene expression in the AML derived KG-1 a cell line. cells were exposed to different concentrations of resver...

Increased risk of early failure of multiply revised total hip arthroplasty

Aims: As the demand for revision total hip arthroplasty (rTHA) grows, understanding how successive revision procedures influence implant survivorship and patient outcomes becomes increasingly important. This study aimed to evaluate the association between revision number and impl...