Society & Economicsarticle2026-10-06

AI and the PI: Infinite Generation, Finite Understanding

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Abstract

Abstract Generative artificial intelligence (AI) produces code and prose quickly, apparently enabling a principal investigator (PI) in a computational group to do more. Assessing this gain must also account for the laboratory’s role in training scientists who understand, maintain, and own their work. AI creates a generation–verification asymmetry: it reduces the effort of producing plausible code and prose without similarly reducing the expertise needed to evaluate them, potentially leaving groups with technical and epistemic debt while obscuring the reasoning needed for supervision. I argue that AI adoption should therefore be judged by whether it builds sustainable laboratory capacity, with assistance adjusted to task purpose and verifiability and human ownership retained for every consequential artifact.

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View paper (DOI)Open access versionOpenAlexJournal of Chemical Information and ModelingPublished 2026-10-06

Authors: Toni Giorgino