Research works

Burdens of pancreatic cancer from 1990 to 2021 and projection to 2050 in China: findings from the 2021 global burden of disease study

<title>Abstract</title> Background Pancreatic cancer in China exhibits high incidence and mortality rates, imposing a significant disease burden. It is essential to clarify the trends in pancreatic cancer from 1990 to 2021 and predict future trends up to 2050, which can provide v...

Hypothalamic recurrent inhibition regulates functional states of stress effector neurons

ABSTRACT Stress triggers rapid and reversible shifts in vital physiological functions from homeostatic operation to emergency response. However, the neural mechanisms regulating such functional stress states remain poorly understood. Here we identify a novel recurrent inhibitory...

Individual differences in speech categorization and perceptual cue reliance across phonological contrasts

Individual listeners differ in how they map acoustic cues onto phonological categories, yet it remains unclear which aspects of categorization generalize across contrasts and how these relate to cue use. This study examines whether differences in speech categorization indices—cat...

Happy Blue Baby

&lt;p&gt;&lt;a href="https://molecular-casenet.rcsb.org/node/5"&gt;Happy Blue Baby&lt;/a&gt;&lt;/p&gt; &lt;p&gt;&lt;em&gt;Overview&lt;/em&gt;: This case explores the reasons for why an otherwise healthy infant turned blue, soon after birth. All tests done in the neonatal intensiv...

COVID-19: Molecular Basis of Infection-ADAPTATION

&lt;p&gt;&lt;a href="https://molecular-casenet.rcsb.org/node/23"&gt;COVID-19: Molecular Basis of Infection&lt;/a&gt;&lt;/p&gt; &lt;p&gt;&lt;em&gt;Overview&lt;/em&gt;: This case is an adaptation of the original COVID-19: Molecular Basis of Infection case which discusses how the SA...

Aligning Clinical Needs and AI Capabilities: A Survey on LLMs for Medical Reasoning

Abstract Large language models (LLMs) have emerged as important tools in healthcare, showing growing potential for clinical reasoning and patient care. This survey examines recent progress in medical LLMs, focusing on reasoning applications and requirements. We present a dual-vie...

Optimal lateral acceleration for different levels of automated driving: a test track study of passenger evaluation for curve negotiation

Lateral acceleration is an element of an AV’s driving style that has a significant effect on comfort, yet its optimal range remains underexplored. This study aimed to understand the optimal zone for lateral acceleration as an AV negotiates curves, investigating the influence of c...

Probiotic-Associated Invasive Infection Among Preterm Infants

This cohort study examines the incidence of invasive bacterial infection associated with probiotic supplementation among preterm infants.

Four years on: following the pathway to real world impact of engineering research

Here we present five short case studies in which key authors of papers originally published in Communications Engineering in 2022 describe the impact of their work four years on. These reflections provide a glimpse of what the papers meant for the key researchers involved, their...

Revealed-behaviour models to map agri-environment contract feasibility for Finland’s semi-natural grasslands and wooded pastures

Abstract Semi-natural grasslands and wooded pastures are biodiversity-rich, declining habitats whose conservation depends largely on voluntary management by farmers. Their management is supported through agri-environment schemes. Effective scheme design benefits from trans- and i...

Guns and Perceptions of Safety Among US Women

Importance: Prior research found differences in the perceived safety benefits from firearm exposure among diverse gun owners. More women have bought firearms in recent years, resulting in a growing proportion of women who own guns. Objective: To examine differences in perceptions...

Male partners’ roles in women’s contraceptive decision-making in Nigeria: a secondary qualitative data analysis

Male partners can play important roles in contraceptive decisions, especially in patriarchal societies like Nigeria, where restrictive gender norms influence women’s reproductive choices. However, little has been explored about how women navigate male influences and its impact on...

From Self-Interest to System Homeostasis: S1, S2, and "Love Your Neighbor as Yourself" Across Nature, Scripture, and Information Systems

Living systems begin with carriers that must preserve boundaries, obtain resources, respond to disturbance, and maintain the capacity to continue. This working paper names that first-order functional interest S1. Once multiple S1 carriers share an environment, their local interes...

Consciousness Is the New Oil: Parallel Paradise Building, Ecstatic Economics, and the Developmental Theory of Value

IDEAS · The Coming Economy — Luminous Prosperity “The empires of the future are the empires of the mind.” — Winston S. Churchill, Harvard University, 6 September 1943 Every civilization runs on a primary resource. Ours ran on the black stuff pulled out of the ground — finite, ext...