Research works

Empirical Antibiotic Initiation for Suspected Early-Onset Neonatal Infection in the Setting of Maternal GBS Screening and Intrapartum Antibiotic Prophylaxis: A Single-Center Retrospective Cohort Study

Background and Objectives: Maternal Group B Streptococcus (GBS) screening and intrapartum antibiotic prophylaxis have reduced early-onset GBS disease. However, suspected early-onset neonatal infection (EONI) remains a broader clinical challenge, as signs prompting empirical antib...

Minority Stress and Mental Health Outcomes in Gender and Sexual Diverse Groups in Brazil: Evidence on the Mediating Role of Social Support

Abstract Sexual and gender minorities (SGMs) face significant health disparities, largely due to chronic exposure to minority stressors that affect mental health. While research documents these harmful effects, few studies examine how discrimination influences emotional responses...

Irisin/Integrin αVβ5/AMPK Signaling in Cardiac Fibrosis: Molecular Mechanisms and Therapeutic Potential

Cardiac fibrosis is a major pathological feature of several cardiovascular diseases and is characterized by excessive extracellular matrix deposition, leading to ventricular stiffening, impaired cardiac function, and ultimately heart failure. Despite its substantial clinical burd...

Dual Machine-Learning Prediction of Excited-State Energetics from Ground-State Descriptors and Its Implication on Intramolecular Singlet Fission in Dimeric Chromophores

Abstract Accurately describing excited-state (ES) properties in large condensed-phase systems remains challenging due to structural flexibility and the limited scalability of quantum methods, both crucial for understanding photo-functional processes such as singlet fission (SF)....

Identification of bacterial communities, structure, and dynamics during cattle and poultry manure composting

Biochar-assisted composting has emerged as a promising strategy for improving the stabilization of animal manure and modifying composting conditions. This study evaluated the physicochemical performance and temporal bacterial succession during in vessel composting of cattle and p...

Determinants and strategies for implementing hepatitis C elimination in low-and middle-income countries: a narrative review with structured literature search

Chronic hepatitis C virus (HCV) infection affects an estimated 56.8 million people globally, resulting in chronic liver disease and a significant economic burden. The World Health Organization (WHO) aims to eliminate HCV by 2030, targeting a 65% reduction in deaths, 80% reduction...

Temporal dynamics of inflammatory proteins in the pre-symptomatic phase of rheumatoid arthritis related to seroconversion

Abstract Objective Autoimmune processes in rheumatoid arthritis (RA) begin years before clinical symptom onset. This study aimed to analyse inflammation-related proteins in individuals during the pre-symptomatic phase, in relation to healthy controls and patients with early RA, a...

Anthropogenic aerosol reduction contributes to faster flash drought onset in a changing climate

Flash droughts have emerged as severe hazards, posing growing challenges to natural and socioeconomic systems, yet the influence of recent aerosol reductions on their onset remains unclear. Here, we investigate the impacts of aerosols and their underlying mechanisms using multi-s...

Involutions in the double Riordan group

In this paper, we investigate the infinite-dimensional representations of the double Riordan group arising from finite double Riordan matrices. We derive a universal construction formula for all double Riordan involutions and then extend this result to the mth-order Riordan group...

NH2 Measurements during the Pyrolysis and Oxidation of Ammonia/Propane Mixtures in a Shock Tube

Abstract Ammonia/propane pyrolysis and oxidation mixtures were studied using NH2 laser spectroscopy to obtain NH2 time histories in a shock tube. An NH3 diagnostic based on a quantum cascade laser was used to verify the initial ammonia concentrations, while a 597.375-nm laser dia...

Artian's Physical Terminal Reference Framework: A Carrier-Independent T-star/Tau Constructor Theorem for Activation-Gated Tests of QTT Axiom A1

When does a physical device contain two genuinely different clock terminals? This framework gives a carrier-independent constructor for a source terminal and a laboratory-written terminal. A four-history experiment becomes eligible only when a completed source event, continuous p...

Perceived changes in mothers’ outcomes following a pilot parenting program for couples with young children in Mwanza, Tanzania: A longitudinal qualitative study

There is growing interest in engaging not only mothers but also fathers in parenting programs to improve nurturing care, psychosocial support, and early childhood development. However, few studies have explored how mothers perceive and benefit from participating in parenting inte...

A python‐based modeling package for underwater acoustic backscatter from individual gas bubbles

Abstract Acoustic backscatter from gas bubbles is key to detecting and quantifying marine seeps and related processes, yet practical tools for target strength (TS) prediction remain limited. We present seaEchoTSCalculator , an open‐source Python package that unifies established t...

DIGITAL TECHNOLOGIES AS A MEANS OF IMPROVING THE METHODOLOGY FOR DEVELOPING PRIMARY SCHOOL STUDENTS' SCIENTIFIC WORLDVIEW IN NATIVE LANGUAGE LESSONS

This thesis examines the possibilities of using digital technologies to improve the methodology for developing primary school students' scientific worldview in native language lessons. The relevance of the study is determined by the need to combine linguistic education with the d...

Geographic Differences in Place Signaling, Inquiry, and Replies: Evidence from Douyin Comments on the Jiangsu City Football League

Background: When a local sports event attracts attention beyond its home region, viewers may participate in different ways. This study examined geographic differences in expressions of connection to the host region, questions, and associations with receiving replies. Methods: We...

Drought Severity Shapes Recovery Trajectories of Root Functions and Rhizosphere Processes in Poa pratensis During a Drought–Rewatering Cycle

Drought–rewatering events are becoming increasingly frequent on the Qinghai–Tibet Plateau, yet how drought severity shapes post-drought recovery of root functions and associated rhizosphere enzyme activities remains unclear. Here, Poa pratensis from Zeku Zequ National Wetland Par...

Engineering Antibody Evolution: Germline‐Targeting HIV Vaccines Reach a Turning Point

This commentary examines three recent Nature studies demonstrating a conceptual shift in HIV vaccine design, demonstrating how germline-targeting HIV vaccines can progress beyond expanding rare broad neutralizing antibody (bnAb) precursors to deliberately guiding their affinity m...

Mobility hinders malaria elimination goals in the Brazilian Amazon

Introduction Human mobility across the Brazilian Amazon—shaped by frontier development, land-use change, mining activity, and climatic shocks—remains a major barrier to malaria elimination. Brazil aims to eliminate Plasmodium falciparum (Pf) by 2030 and Plasmodium vivax (Pv) by 2...

Challenges of parliamentary engagement in health policymaking in Iran: a qualitative study using Gaventa’s power cube framework

Parliaments play an important role in health governance through legislation, budgeting and oversight. However, their practical influence on health policy decisions remains poorly understood in systems where executive institutions and expert actors dominate policy processes. In Ir...

Capacity Utilization and Its Impact on Airline's Financial Performance: Evidence From the U.S. Airline Industry

ABSTRACT Capacity utilization, operationalized as passenger load factor, is the airline industry's primary efficiency metric, yet evidence on its financial return remains inconsistent. We attribute the contradictions to two deficiencies: econometric methods that conflate cross‐se...