Research works

Digital health capacity building across health workforce and education sector in the WHO European region

Abstract Disparities in digital capacity building across countries highlight the need for global upskilling. This study examined digital health capacity building across policy, workforce, and pre-service education domains across 53 countries of the WHO Europe Region. This was a c...

Bite mechanics within the wolf lineage: feeding capabilities of Canis borjgali and Canis mosbachensis inferred by digital bite simulation

Abstract Genus Canis species plays a key role as predator in terrestrial ecosystems. However, the evolutionary history of these carnivorans is still not fully understood. To explore this topic, we studied the bite of two fossil close relatives of the modern grey wolf, Canis borjg...

Serological and transcriptomic response of African fruit bats to immune challenge with recombinant vaccines expressing Ebola or Nipah virus antigens

Abstract Bats are hosts to diverse zoonotic viruses which can cause high case fatality rates in humans. Since detecting viruses in bats is difficult, antibodies are often used for surveillance, though their significance remains unclear in the absence of in vivo immunological stud...

Developmental divergence in gene regulation underlies trophic innovation in Lake Victoria cichlids

Abstract The role of developmental shifts in the emergence of ecological diversity during adaptive radiation remains largely uncharacterized. Here, we investigate the developmental gene regulatory landscape of trophic innovation in the rapid adaptive radiation of cichlid fishes f...

Season-dependent phenological responses and implications for co-occurring plants and butterflies under climate anomalies and extreme weather events

Abstract Despite extensive work on climate-driven phenological shifts, research has focused primarily on early-season events, single metrics and gradual shifts in mean climate, limiting insights into phenological responses across the full annual cycle. Using a 17-year dataset (20...

Ecological responses of soil bacteria to rapid and slow temperature fluctuations

Abstract Fluctuating temperatures profoundly affect microorganisms’ coexistence, biogeographic distributions and responses to future climate change. However, how microorganisms respond to fluctuating temperatures with different frequencies in natural communities remains unknown....

Competing methods of divergence time estimation recover diverse evolutionary timescales

Abstract Molecular clocks convert evolutionary distances into geological times to infer time-scaled phylogenies. Methods differ in terms of fossil calibration strategy (node versus tip) and whether they use molecular and/or morphological data, but their relative performance remai...

The Portable Clinical Obligation: a patient-held, condition-agnostic registry for closing diagnostic follow-up loops worldwide

Across every health system studied, a substantial fraction of correctly-made diagnoses and correctly-written follow-up recommendations are never acted on. The detection succeeded; the linkage failed. Reported failure rates range from roughly a quarter to a half of actionable inci...

Nonlinear dispersive waves in the discrete modified KdV equation

Abstract In this paper, we study the nonlinear dispersive waves including the numerically observed rarefaction and dispersive shock waves in the discrete modified KdV equation which has widespread applications in plasma physics. In particular, we propose three distinct quasi-cont...

Balancing training load, rest and musculoskeletal injury risk: a mathematical modelling study in Thoroughbred racehorses

Abstract Musculoskeletal injuries (MSI) in Thoroughbred racehorses are a leading cause of death and premature retirement, and are heavily influenced by training practices. Greater distances of high-speed galloping accumulated during racing campaigns are associated with MSI. Bone...

Guided elastic waves informed material modelling of soft incompressible media

Abstract Identifying a universal material constitutive law which describes the mechanical response of rubber-like solids for all deformation fields and achievable extensions, is an outstanding challenge. Here, we propose to exploit the propagation of elastic waves and demonstrate...

Watanabe–Strogatz invariants in the Liouvillian dynamics of coupled phase oscillators via the Koopman framework

Abstract In dynamical systems, invariants, i.e. constants of motion conserved along the trajectory, play important roles in characterizing the system's dynamical behaviour. Recent applications of the Koopman operator framework to nonlinear dynamical systems have provided new insi...

Associations between urban form and urban multifunctionality: a comparative study

Abstract Cities are complex and dynamic systems that integrate social, ecological, and infrastructure domains. This study investigates and quantifies how urban forms are associated with multiple urban functions across these domains, and how these associations combine into positiv...

Dislocation dynamics on deformable surfaces

Abstract We develop a fully coupled theoretical description of dislocation dynamics on deformable crystalline surfaces, using continuum modelling and the amplitude-phase-field crystal (APFC) framework extended to curved geometries. We derive a general kinematic expression for dis...

A mathematical theory of redox biology

Abstract Redox biology is commonly described through functional labels, such as oxidant, reductant, antioxidant, signalling mediator or damage mediator. However, these labels do not define invariant molecular properties. A molecule may realize different functions depending on rea...

From random walks to thermal rides: universal anomalous transport in soaring flights

Abstract Cross-country soaring flights rely on intermittent atmospheric updrafts to cover long distances, producing trajectories that alternate between rapid relocation and local exploration. From a large dataset of paraglider, hang glider and sailplane flights, we uncover a univ...

Bracing in adult scoliosis: a scoping review of clinical outcomes

Bracing is commonly used as a conservative treatment for scoliosis, but its effects in adults with scoliosis remain unclear. To map and synthesize the existing evidence on the effects of bracing in adults with scoliosis, focusing on radiological outcomes, pain, physical function,...

Agriculture–urban interfaces, social vulnerability and climate change shape West Nile virus risk across the United States

Abstract Climate and land use change are reshaping the dynamics of vector-borne diseases. West Nile virus (WNV), the most widespread zoonotic arbovirus in the United States, illustrates the need to integrate climate, land cover and social vulnerability across heterogeneous landsc...

Collective adsorption of pheromones at the water–air interface

Abstract Understanding the phase behaviour of pheromones and other messaging molecules remains a significant and largely unexplored challenge, even though it plays a central role in chemical communication. Here, we present all-atom molecular dynamics simulations to investigate th...

ANALISIS STRATEGI PENCEGAHAN PELANGGARAN LALU LINTAS OLEH POLRES SELUMA DALAM PERSPEKTIF FIQH SIYASAH

Tingginya angka pelanggaran dan kecelakaan lalu lintas di Kabupaten Seluma menunjukkan bahwa upaya pencegahan belum sepenuhnya mampu meningkatkan kesadaran hukum masyarakat. Kondisi tersebut menuntut penerapan strategi kepolisian yang efektif serta selaras dengan ketentuan Peratu...