Research works

Local Structure and Dynamics of Three-Dimensional Covalent Organic Frameworks

Abstract Resolving and controlling the local dynamical properties of covalent organic frameworks (COFs) remains a central challenge, particularly when assembled from large, flexible building units. Here, we combine synchrotron X-ray pair distribution function (PDF) analyses with...

ExonViz: Transcript visualization made easy

ExonViz is a simple tool to draw transcripts that include coding and non-coding regions. All exons are to scale and the reading frames of the exons are visible. Single or multiple variants along the transcript can be drawn and will automatically be shown in the correct location.

Procrastination among US college students: Prevalence and impact relative to common health and life issues

Procrastination is unnecessary delay that can cause various problems. There are uncertainties around how common exactly it is among students, how much it affects them, and how its prevalence and impact compare to those of other issues that students regularly face. Accordingly, th...

Prediction of prognosis and treatment effect of cervical cancer by immunogenic cell death-related genes

Background Immunogenic cell death (ICD) is a potential mechanism that mediates adaptive immune responses during anticancer therapy. However, expression patterns and clinical implications of ICD related genes in cervical squamous cell carcinoma and endocervical adenocarcinoma (CES...

A comparative analysis of graph neural networks through similarity-based information propagation across diverse network structures

Abstract Information propagation over graph-structured data depends critically on the quality of node representations learned by graph neural networks (GNNs). However, how different GNN architectures organize embedding spaces and how these representations influence downstream pro...

Epigenetic insights into extreme longevity in the world’s oldest terrestrial animal, Jonathan

Aldabra giant tortoises ( Aldabrachelys gigantea ) are exceptionally long-lived. We sequenced the genome and methylome of Jonathan, a 194-year-old Aldabra, to explore the molecular basis of his longevity. Relative to other giant tortoises ( A. gigantea and Chelonoidis abingdonii...

Reliability of machine learning methods for prediction of critical heat flux: an OECD/NEA benchmark study

Abstract Critical heat flux (CHF) prediction is a primary thermal-hydraulic requirement for water-cooled reactors. Machine-learning studies on the OECD/NEA Phase-1 benchmark report high in-distribution accuracy, but reliability under distribution shift is poorly characterised. Fo...

Cryptanalysis of multiparty key exchange protocols over a modified supertropical semiring

We present a cryptanalysis of a multiparty key exchange protocol over a modified supertropical semiring, as proposed in a recent work of R. Ponmaheshkumar, J. Ramalingam, and R. Perumal. Building on the established methods for solving linear systems A⊗x=b over the tropical semiri...

Evolution of dipole–dipole dynamics in cold ammonia collisions

Cold polar molecules offer fascinating prospects for ultracold chemistry and quantum physics. However, their inherent collision properties remain largely unknown, as it seems fundamentally impossible to reach sufficiently low energies by merging two beams of molecules with substa...

BioForge: A Fast and Safe Macromolecular Structure Preparation Library in Rust

Abstract Summary BioForge is the first macromolecular structure preparation library for Rust, complementing sequence-analysis libraries such as Rust-Bio with cleaning, geometry-based missing-atom repair, protonation, and solvation as a force-field-agnostic preprocessing stage. Ac...

Effects of Mineralogical Inhomogeneity on Aggregate Dust Optical Properties and Lidar Observables

Abstract Dust aerosols comprise irregular grains and aggregates with various mineralogical mixtures. However, most optical models use effective refractive indices to represent particles. This study develops an inhomogeneous aggregate model assigning mineral‐dependent refractive i...

Ways of improvement of struggling School Children in Nepali Subject: An Action Research

Sometimes, young children find it difficult to learn Nepali concepts, leading to a situation where their grades start falling, especially in public schools in the Kathmandu valley. This paper tells us about the possible reasons behind students' struggles in subjects like Nepali a...

Animal-Assisted Interventions in Custodial Settings: A Systematic Review of Psychological Wellbeing Outcomes

The use of animal-assisted interventions (AAIs) to support incarcerated individuals’ psychological wellbeing has expanded rapidly in recent years. However, research in custodial settings remains limited and is largely characterized by methodologically weak study designs that rely...

Detecting clear-air turbulence via beam broadening in a Rayleigh-scattering lidar system

The volume of clear-air turbulence (CAT) in the atmosphere at flight cruising altitudes is increasing rapidly, posing a growing problem for civil aviation and resulting in reduced confidence in aviation safety. There are limited remote detection capabilities for CAT, since clear...

Game theory driven multi-agent framework mitigates language model hallucination

The application of lightweight Large Language Models in rule-based scientific domains remains severely limited by their tendency to mimic linguistic patterns rather than reproduce axiomatic reasoning, causing frequent hallucinations. Here, we show that G-Frame, an adaptive multi-...

Signatures of photospheric convection throughout the solar atmosphere: the EVE Sun-as-a-star mHz continuum

Abstract Convectively driven motions in the solar photosphere can generate broadband Doppler variability across the chromosphere, transition region and corona. Here we investigate this variability using “Sun-as-a-Star” observations from the Extreme Ultraviolet Variability Experim...

Shape analysis in Schauder spaces of the energy of heat problems in perturbed annular domains

This paper is devoted to the shape analysis of the energy of a caloric family of Schauder functions defined on a bounded perforated domain $Ω^o \setminus \overline{Ω^i[ϕ]}$ of $\mathbb{R}^n$, where the outer boundary is fixed, and the inner boundary is obtained by a $C^{1,α}$-per...

Exact analytical solutions for the piston effect in supercritical fluids under post-acoustic approximation — Short-time asymptotics, thermal penetration depth and comparison with the Spacelab D-2 experiments

Near the liquid–vapor critical point, fluids become highly compressible, giving rise to a special, strongly coupled thermo-mechanical process: the piston effect. In this phenomenon, a thin thermal boundary layer develops near a heated wall; owing to strong thermal expansion, this...

From “More Is Different” to Algorithmic Emergence: Regularity, Compression, and the Limits of Discovery

Scientific discovery seeks regularities that support explanation and prediction. Compression makes their reuse explicit: shared structure is described once, while parameters specify individual cases. A model can, therefore, pay for itself through repeated use even when its descri...

Aziridination-Based Crosslinking Enables Site-Resolved Elucidation of Lipid Binding and Protein Conformational Changes

Abstract Lipid–protein interactions play critical roles in cellular function, yet their site-resolved characterization remains challenging due to the dynamic nature of lipid binding and the limited availability of chemoselective strategies for covalently capturing native lipid–pr...