Research works

Neurogenic bladder in the multiple sclerosis population: A systematic review and meta-analysis of prevalence and a proposed evaluation algorithm

BACKGROUND: Neurogenic bladder (NGB) is one of the most common and debilitating manifestations of multiple sclerosis (MS), substantially impairing quality of life and increasing the risk of secondary complications. OBJECTIVE: To determine the pooled prevalence of NGB and its subt...

Congenital/primary clival meningocele: A systematic review and surgical approach based on a new proposed classification

Skull base meningoceles are extremely rare, most commonly resulting from congenital defects in sphenoid bone fusion. Inadequate embryonic fusion between the posterior sphenoid and the occipital bones may result in a transclival meningocele. Given the absence of a formal classific...

The evolution of thyroid cancer diagnostics: Historical milestones and their impact on contemporary clinical practice

Thyroid cancer represents the most prevalent malignancy of the endocrine system, with its incidence exhibiting a significant rise in recent years. Diagnostic methods have undergone profound evolution over the past century, progressing from basic clinical examination to a sophisti...

CMIP6 Historical Evaluation and Future Changes of Climate Extreme Indices at Regional Scale From the US ‐Mexico Border Region to Central America

ABSTRACT This study evaluates seven climate extreme indices (CEIs) of precipitation and temperature and assesses their potential changes in 15 regions of the CORDEX‐CAM domain (from the southwestern United States to Central America) for different periods: historical (1981–2010),...

Surface microbial dynamics and residual diversity in patient rooms with wooden and painted walls

Wood is a biobased material that supports long-term carbon storage; however, its suitability for use in healthcare facility interiors remains insufficiently studied. This study assessed surface microbial dynamics and residual diversity in patient rooms with conventional painted w...

Prevalence of Keshan disease at the township level in China: a cross-sectional study

Keshan disease (KD), an endemic myocardiopathy with unclear etiology, lacks primary preventive measures. This study aimed to assess the prevalence of KD at the township level using spatial epidemiology, elucidate its distribution characteristics for further precision classificati...

A GHz-Gated Dual-Anode InGaAs/InP SPAD Front-End for OAM Cat-Qubit Syndrome Extraction

The OAM cat-qubit encoding developed in a companion note [1] defines an operationalprotocol for extracting the channel’s mode-hopping rate γ from the linear growth of OAMpopulation variance, Var(l) = γz, measured via repeated single-photon counting at the outputports of a telecom...

Patient-physician sex concordance and real-world disparities in cancer treatment practices and outcomes in medical oncology

The impact of sex inequities in healthcare may be magnified in medical oncology, where patients and physicians often navigate life-limiting illnesses and intensive treatments. We examined the associations among patient-physician sex concordance, treatment practices, and cancer ou...

Disarming Pseudomonas aeruginosa: repurposing vardenafil, valsartan, and olmesartan as anti-virulence and antibiofilm agents

Abstract The rapid emergence of antibiotic resistance represents a critical global health challenge, particularly in biofilm-associated infections caused by Pseudomonas aeruginosa ( P. aeruginosa ). Quorum sensing plays a pivotal role in regulating bacterial virulence and biofilm...

PEMTCL: A Prompt-Enhanced Multi-Task Contrastive Learning Framework for Fine-Grained Toxic Language Detection

Fine-grained toxic language detection aims to assess the harmfulness, expression style, and attack target of textual content, supporting refined content moderation on online platforms. Most existing methods model each subtask independently, failing to exploit semantic correlation...

Contrasting Soil Chemical and Microbial Responses to Moderate Thinning in a South Swedish Spruce Forest

Abstract Small-scale forest owners frequently implement thinning to enhance stand productivity, improve timber quality, and maintain structural diversity; however, its short-term effects on soil physicochemical and biological properties remain insufficiently understood. This stud...

Examining the role of actual behavioral control in adolescent upcycling behavior

This study was conducted to explore upcycling behaviour using the knowledge, attitude, and practice (KAP) model, incorporating actual behavioural control (ABC) as a moderating variable. While previous studies on upcycling have primarily focused on the industrial sector’s perspect...

A Pterostoma from the Eocene, Anglesea, Victoria, Australia

This palaeobotanical note describes a specimen of Pterostoma that was recovered from Eocene coal measures within the open cast Anglesea coal mine, Victoria, Australia. The specimen is significant as it clearly shows venation.

The postsynaptic scaffolding protein SAPAP3 shapes mitochondrial activity: the case of Huntington’s disease

Abstract Postsynaptic scaffolding protein SAP90/PSD95-associated protein 3 (SAPAP3) modulates cortico-striatal signalling and regulates the maintenance of synaptic structure. Notably, SAPAP3 defects have been reported in several human psychiatric disorders that share pathophysiol...

Transition MetalSulfides Supported on SulfonatedCNT-Chitosan Derived Carbon Aerogel for Efficient Electrooxidationof 5-Hydroxymethylfurfural to 2,5-Furandicarboxylic Acid

Abstract In this study, we present a straightforward synthesis strategy to prepare transition metal sulfide electrocatalysts supported on sulfonated carbon nanotube-chitosan-derived carbon aerogel. Highly dispersed Ni3S2@CNT, Cu7S4@CNT, and Co4S3@CNT were successfully fabricated...

Validation of STARZ scoring in very low birth weight (VLBW) neonates in the United States

Abstract Background Acute kidney injury (AKI) is a significant complication in very low birth weight (VLBW) neonates, associated with increased morbidity, mortality, and prolonged hospitalization. Early identification of at-risk infants enables timely interventions. The STARZ sco...

Nano-enhanced PCM-assisted solar stills: A systematic review of performance, economics, and sustainability

Abstract Freshwater scarcity is an escalating global challenge, particularly in arid, remote, and off-grid regions where conventional desalination technologies remain energy-intensive and costly. Solar stills provide a simple and sustainable desalination option; however, their br...

Clinical outcomes of linear accelerator-based stereotactic radiosurgery for trigeminal neuralgia

Background: Trigeminal neuralgia (TN) is a severely disabling facial pain disorder. When medical treatment fails, stereotactic radiosurgery (SRS) is an established option. The Gamma Knife is widely used but not always available. This study assessed the efficacy and safety of line...

Mitochondrial subpopulations in oocytes and cumulus cells exhibit distinct age-associated changes and selective plasticity in response to NMN supplementation

Abstract Background Mitochondrial dysfunction is a leading contributor to the decline in oocyte quality associated with maternal aging. Prior investigations of mitochondrial function in the ovarian follicle have largely treated the mitochondrial pool as a homogeneous population,...

Two-year efficacy and safety outcomes of the Paul Glaucoma Implant compared to the Ahmed Glaucoma Valve

PURPOSE: To compare efficacy and safety profiles of the Paul Glaucoma Implant (PGI) and Ahmed Glaucoma Valve (AGV) in the treatment of adults with glaucoma over a 2-year of follow-up period. METHODS: This retrospective, single-center, comparative study included adult patients who...