Research works

“Something is not right”: caregivers’ and educators’ perceptions of developmental concerns in toddlers at elevated likelihood of autism

The pre-diagnostic period before an autism diagnosis is a critical yet underexplored phase for families and educators. This study aimed to explore how family caregivers and educators experience the pre-diagnostic period of toddlers at elevated likelihood of autism, focusing on pe...

Optical appearance of the Kerr–Bertotti–Robinson black hole with a magnetically driven synchrotron emissivity model

Abstract We investigate the optical appearance of a Kerr–Bertotti–Robinson (Kerr-BR) black hole illuminated by a geometrically and optically thin accretion disk. Instead of using a phenomenological power-law emissivity, we adopt a magnetically driven synchrotron emissivity proxy...

Issues in the clinical assessment and management of people living with motor neurone disease (MND): a survey of Australian healthcare professionals

Objective: To inform the development of the Australian MND Guideline, this study aimed to identify challenges Australian healthcare professionals (HCPs) face in the clinical assessment and management of people living with MND (plwMND) including where practice varies from evidence...

Geographic Access to Care and Mortality in Cardiogenic Shock: A Nationwide Cohort Analysis

IMPORTANCE: Timely access to advanced care is critical for patients with cardiogenic shock (CS), yet the impact of regional disparities in hospital arrival time on mortality remains unclear. OBJECTIVES: To investigate whether regional disparities in hospital arrival time are asso...

Broad graph convolutional network: a novel graph convolutional network paradigm without hidden layer

Abstract Graph convolutional networks (GCNs) have shown promising performance in real-world applications involving graph-structured data. To enhance the model’s ability to integrate information from neighbor nodes, GCNs typically expand the receptive field by stacking more layers...

Severe multi-site abscesses and necrotizing fasciitis in a young patient with diabetes

Introduction: Multifocal abscesses in young patients are uncommon and may signal underlying genetic or immune defects. Case presentation: A 20-year-old woman with maternal diabetes and consanguinity presented with hip pain and fever after a minor fall. Examination revealed short...

The impact of Solution Focused Practice on workplace wellbeing: a systematic review

Solution Focused Practice is a collaborative approach that focuses on resources and what is already working to support people in reaching preferred futures. It has expanded from its original roots in therapy to areas such as coaching and consulting and is often used in a range of...

A Conceptual Trauma-Informed and Ecological Framework for Integrating Caregivers into Healthcare Oncology Care Settings

Caregivers play a central role across the cancer trajectory, yet their needs often remain insufficiently recognized within routine oncology workflows. This conceptual manuscript proposes a trauma-informed, ecological, and interprofessional model designed to support the systematic...

Mapping basal ganglia circuitry in altered states of consciousness: from pathology to pharmacology

The precise neuromodulatory mechanisms underlying consciousness and its disorders, despite growing evidence in both animals and humans, remain poorly understood at the subcortical level. The basal ganglia, a key component of the cortico-basal ganglia-thalamo-cortical loop, are kn...

Water-Saving Attitudes in Residential Gardens: Exploring Climate Change Exposure, Risk Perception, Belief, and Environmental Efficacy

Abstract As climate change intensifies, understanding the psychological and contextual factors that shape water-saving attitudes in residential gardening is increasingly important, particularly in arid and semi-arid countries such as Iran. This study examines how climate-related...

An unexpected pleomorph: a case report of a rare back lipoma in a female

Pleomorphic lipomas are rare, benign adipocytic neoplasms most commonly arising in the subcutaneous tissues of the posterior neck, upper back, and shoulders. They show a strong predilection for middle-aged to elderly men; however, occasional cases have been reported in women and...

The skin of sorrow. The controversies between protected areas and tourism in a context of glacial retreat: Grande Motte (Tignes) and Girose (La Grave), France

The aim of this article is to identify the sources and drivers of conflict and conciliation in the case of two glacier redevelopment projects, drawn up in response to operating difficulties caused by climate change–driven glacial retreat and the declining popularity of summer ski...

From propofol to cipepofol (Cypsedo®), a new intravenous general anesthetic approved for adults undergoing surgery

Propofol ( 1 ) remains the gold standard intravenous general anesthetic despite such drawbacks as injection pain, respiratory depression, and cardiovascular instability. The newly FDA-approved cipepofol (Cypsedo ® , 2 ) is a chiral analog incorporating a cyclopropyl ring to enhan...

Community metabolism in dynamic redox landscapes

Microbial communities are fundamentally shaped by the diverse metabolic processes through which microbes extract energy from the chemical and light-driven potential gradients in their environment. Thus, predicting microbial community dynamics requires a quantitative framework gro...

Adherence and Healthcare Costs Associated with Single-vs Free-Pill Combination of Perindopril-Based Antihypertensive Medications: An 11-Year Follow-Up, Real-World Evidence

BACKGROUND: Short-term studies have demonstrated that single-pill combinations (SPCs) improve adherence, reduce hypertension-related complications, and lower costs; however, long-term benefits remain unclear. This study compared adherence, healthcare resource utilization (HCRU),...

Estimating the technical efficiency of offshore fisheries in Sri Lanka and evaluating the impact of digital technology

As marine resources decline rapidly, integrating digital technologies with traditional fishing practices has become essential for improving resource efficiency and achieving sustainable economic outcomes. This study estimates the technical efficiency of Sri Lanka's inboard multid...

Towards standoff concealed object detection using false-color near-infrared imaging and deep learning: A preliminary study on detecting the presence of metal and PVC pipes under clothing

Detecting concealed hazardous objects beneath clothing is crucial for security; however, existing sensing modalities may pose safety, privacy, or operational limitations. Millimeter wave (MMW) and terahertz (THz) imaging systems are effective at close range, but suffer from reduc...

General Movement Assessment in infancy and later cognitive outcomes: A systematic review and meta‐analysis

The General Movements Assessment (GMA) is a brief assessment of how babies move in the first months of life. It is commonly used to help identify infants at risk of neurodevelopmental conditions such as cerebral palsy. Researchers and clinicians have increasingly wondered whether...

Observed CTIT onset timing is associated with platelet surveillance schedules in a real-world cohort

Chemotherapy-induced thrombocytopenia (CTIT) is detected through platelet testing, so routine-care estimates of onset and recovery may depend on surveillance schedules. We characterized within-cycle timing and assessed whether apparent differences among drug categories persisted...

Evaluating raw versus body-weight–normalized McGill core endurance composite scores in recreational weightlifters: implications for strength and functional performance

The effectiveness of using McGill trunk endurance scores as raw values or body-weight-normalized metrics remains uncertain for evaluating weight classes, especially given the increasing number of recreational weightlifters. The study compared the raw McGill composite score with t...