Research works

The Tetractys-E8 Fractal Resonance Protocol for Non-Linear Market Fluctuations — E8 Intelligence Research

By mapping the Tetractys generative matrix onto the 240 E8 root vectors, we derive a stochastic periodicity where market order-flow volatility is treated as a phase-locked vibration. This protocol uses the 132Hz base frequency to identify "Triangular Harmonic Spikes," where price...

Seminal Plasma Kisspeptin‐1 and Kisspeptin‐54 Levels Are Associated With Semen Parameters and Oxidative Stress in Male Infertility

ABSTRACT Objective Kisspeptin‐1 and Kisspeptin‐54 are key regulators of the hypothalamic–pituitary–gonadal axis and may play a role in male reproductive function. This study aimed to evaluate the association between seminal plasma kisspeptin levels and male infertility, and to ex...

Kinetic Flat-Histogram Simulations of Non-Equilibrium Stochastic Processes

To our knowledge, there is no flat-histogram algorithm to sample the stationary distribution of non-equilibrium stochastic processes. The present work addresses this gap by introducing a generalization of the Wang-Landau algorithm, applied to non-equilibrium stochastic processes...

The Vaccination Protocol: Epistemic Friction, Sycophancy, and Bidirectional Cognitive Cost in Human-LLM Interaction

Large language models are commonly optimized not only for task performance but also for helpfulness, social acceptability, safety, and user preference. A growing literature shows that these objectives can conflict: human and preference-model feedback can reward agreement over tru...

Engineered desialylated platelet membrane camouflaged liposomes for the regulation of kupffer cells and hepatic stellate cells in treatment of liver fibrosis

The intercellular crosstalk and reciprocal activation between Kupffer cells (KCs) and hepatic stellate cells (HSCs) are critical drivers of liver fibrosis progression. Nonetheless, the co-regulation of KCs and HSCs is hindered by their distinct anatomical locations and the pathol...

Joint scheduling of distributed mixed-line high-speed train bogie maintenance: a multi-agent hierarchical deep reinforcement learning approach

Distributed mixed-line reassembly has emerged as a vital paradigm for high-speed train bogie maintenance. However, spatio-temporal heterogeneity complicates the joint scheduling of line assignments, operations and heavy component transportation. Because reassembly and transport c...

E8‑Golden‑Ratio Quantum Lattice Communication Protocol (E8‑GQCP) — E8 Intelligence Research

By mapping each of the 240 E8 root vectors to a distinct sub‑carrier at 132 Hz and locking their phase relationships through the golden‑ratio coupling (φ), the protocol creates a self‑referential interference lattice that can simultaneously transmit orthogonal quantum information...

The Universe Is A Program, Representations Issues (Version I)

The goal of this paper is to Compose new methods and processes. The Universe as a Program is a reprensentation to start composing all of existing and living entities (in the Universe). We argue important representations issues. Many new findings will be presented.

Multi-scale Evaluation of Rutting Resistance in Reclaimed Asphalt Pavement Mixtures through Linking Binder Rheology with the Hamburg Wheel-Tracking and the IDEAL Rutting Tests

This study proposed a multi-scale framework for evaluating rutting resistance in recycled asphalt mixtures by linking binder rheology with mixture-scale performance. One virgin mixture and seven mixtures containing 50% reclaimed asphalt pavement (RAP) were prepared with three rej...

Cholera endemicity as a systems failure: a STAMP-CAST investigation in Kakuma and Dadaab refugee complexes in Kenya

Abstract Background Cholera outbreaks continue to pose a significant public health threat in Kenya and other low-and middle-income countries, particularly in humanitarian settings where overcrowding, inadequate water and sanitation services, population mobility, and climate-relat...

Intraoral Scanners: Enhancing Dental Education

ABSTRACT Introduction This study evaluated how integrating intraoral scanners (IOS) into Digital Dentistry and Operative II courses at Tufts University School of Dental Medicine (TUSDM) influenced second‐year dental students' perceived understanding of ceramic inlay preparations...

Structural insights into a substrate translocation pathway revealed by the RND efflux pump complex MexJK from Pseudomonas aeruginosa

Resistance–nodulation–cell division (RND) efflux pumps are the major cause of multidrug resistance in Pseudomonas aeruginosa . The inner membrane protein MexK from P. aeruginosa is a narrow-spectrum RND transporter. It assembles with membrane fusion protein MexJ and outer membran...

Deep Mycobacterium marinum Infection of the Digit Presenting Without Cutaneous Lesions: A Case Report

Mycobacterium marinum is a slow-growing nontuberculous mycobacterium acquired through breaches of the skin during contact with fish or aquatic environments. It classically produces a cutaneous papulonodular lesion of the hand, but deeper involvement of tendon sheaths, joints, and...

OvercomingElectrochemiluminescence Immunoassay (ECLIA)Limitations: Conformation-Independent Quantitation of a TherapeuticAntibody by LC–MS/MS

Abstract Monoclonal antibody therapies have transformed cancer treatment by enabling targeted intervention even in advanced disease stages. However, reliable monitoring of circulating therapeutic antibody levels is critical to ensuring efficacy and patient safety. This study inve...

Global Mittag–Leffler synchronization of fractional-order Clifford-valued neural networks with mixed time-varying delays via adaptive quantized pinning control

Abstract The objective of this paper is to establish verifiable synchronization criteria for fractional-order Clifford-valued neural networks with mixed time-varying delays when the response system is controlled through finite-resolution communication channels. The model contains...

Anorectal manometry after rectal cancer surgery: physiological insights, clinical interpretation, and limitations

Abstract Anorectal manometry (ARM) provides objective physiological information on anal sphincter function, rectal or neorectal sensation, reservoir capacity, and anorectal reflexes after rectal cancer surgery. In rectal cancer surgery, ARM has been used to evaluate functional ch...

Enrollment is not coverage: integrity gates, their measured detection rates, and the limits of self-checking documentation

This is an experience report with n = 1, self-reported: the same author wrote the documents, the gates that check them, and this account of what the gates found, and no independent party re-ran anything. Every structural failure it describes was found by the apparatus catching it...

Computer Vision-Based Information Extraction from Electrical Assets: A Systematic Literature Review

Automated inspection of electrical equipment has become increasingly important as utilities seek to replace inefficient manual processes in infrastructure management. Electrical-equipment nameplates contain critical technical information, but automatically extracting this informa...

A Stabilizer Obstruction for Anonymous and Object-Neutral Classification Aggregation

We disprove a conjectured prime-divisor characterization for anonymous and object-neutral classification aggregation. A general stabilizer obstruction and explicit profile gadgets show that, for every m ≥ 5, ρ = m − 2, and n ≥ 2, no deterministic resolute anonymous and object-neu...

‘The real win is doing this for a living’: Routes, routines and rewards of music managers

Studies of the music industry have traditionally prioritized its creative dimensions, especially musicians’ activities. When ‘non-creative’ aspects of music creation are examined, they are typically approached through musicians’ own ‘non-creative’ activities. Despite the insisten...