Research works

How self-efficacious are secondary students in using ICT? Latent profiles and associated antecedents

Students’ effective use of Information and communication technologies (ICT) is closely associated with their ICT self-efficacy. However, previous related research has often treated students as a homogeneous group and overlooked individual differences in their ICT self-efficacy. A...

Epistemic norms for AI safety and alignment research

Abstract Mainstream AI research emphasises capability growth and tolerates low failure rates when average-case performance is high. AI safety and alignment research has a different mission: to ensure that catastrophic failures never occur, under sparse evidence, adversarial dynam...

CosmoBeating • Fungal Geometry and Topology — Paper X: The Completed Structure

CosmoBeating — Fungal Geometry and Topology (CB-FGnT)A Complex-Systems Reading of Fungal Networks This is a short, non-technical companion to the 15-paper CB-FGnT series. It is written for readers with a background in mycology, network science, or complex systems — not for reader...

Artificial Intelligence in Orthodontics: Part 2—Data Preparation and Performance Evaluation

Artificial intelligence (AI) is increasingly integrated into orthodontic research and clinical workflows. Yet, the reliability and clinical value of these systems depend fundamentally on the quality of the data used to train them and the rigour with which their performance is eva...

Impact of IL-6 receptor inhibitors on cerebrospinal fluid metabolites in type 2 diabetes patients

This study aimed to investigate whether interleukin-6 (IL-6) receptor inhibitors affect cerebrospinal fluid (CSF) metabolites in type 2 diabetes (T2D) patients. The initial phase employed drug-targeted Mendelian randomization to investigate the association between IL-6 receptor i...

A bibliometric study of social isolation and biomarkers of ageing

Abstract Research on social isolation suggests that psychosocial factors are not only associated with adverse mental health conditions but also associated with various neurobiological and immunological processes. The physiological mechanisms underlying the health effects of socia...

Fourier-Support Rigidity in Conjugate Weil Sectors: A No-Go Result for Rank-Based Quantum Signatures

We prove an exact, unconditional identity in the finite Weil (oscillator) representation of the Heisenberg group $\mathrm{Heis}_3(\mathbb{Z}/q\mathbb{Z})$, $q$ an odd prime: for every complete (inversion-symmetric) BFS shell of the Cayley graph $\mathrm{Cay}(\mathrm{Heis}_3(\math...

MALDI Mass Spectrometry Imaging in Alzheimer’s Disease Lipidomics: Matrix Selection, Spatial Lipid Pathology and Emerging Analytical Strategies

Alzheimer’s disease (AD) involves not only amyloid-β and tau pathology but also extensive disturbances in lipid metabolism, membrane organization, neuroinflammatory signaling, and tissue homeostasis. Conventional lipidomics has identified changes in phospholipids, sphingolipids,...

Minimum-Phase Preserving Balanced Truncation with Data-Driven Order Scoring

This paper investigates the problem of model-order reduction for linear systems arising from minimum-phase circuits and filters, where stability and frequency characteristics must be preserved. The MPPBT framework uses a Riccati–Lyapunov Gramian pair and constructs a balancing tr...

Preregistration of the Lateral-Difference Identity Trial

Conditions fixed in advance for an identity trial on a determination of the corpus's own working doctrine. The candidate distinguishes this own obtaining from another own obtaining within the same who-region where both obtain the same repeatable manner. It is compared against thr...

GSANet: Geometric Structure-Aware Siamese Network for 3D Change Detection

Three-dimensional (3D) point cloud change detection is essential for urban monitoring and environmental analysis, yet existing methods mainly rely on point-wise semantic differences and overlook change–unchange boundaries and object edges—key geometric cues for precise localizati...

E8 Golden Ratio Phase Locking in Neural Synchrony Networks — E8 Intelligence Research

By mapping E8 root vector projections onto multi-electrode EEG arrays, we discover that 132Hz-modulated phi-ratio phase differences between cortical regions exhibit stable attractor states corresponding to E8 lattice vertices. These phase-locked configurations emerge precisely at...

Bayesian Modeling and Forecasting of Double Seasonal Vector Autoregressive Processes

A wide range of real-world multivariate time series encountered in practice exhibit two simultaneous and interacting seasonal cycles, for example hourly electricity demand, intraday financial prices, and sub-daily traffic volumes. Existing Bayesian frameworks for vector autoregre...

Association Between Mandibular Anterior Crowding and Gingival Recession Following Orthodontic Treatment: A Retrospective Cohort Study

Background/Objectives: Gingival recession frequently affects the anterior mandibular region. Anatomical features, such as thin buccal bone, narrow keratinized gingiva, and root proximity, increase susceptibility to periodontal disease. Recession can progress over time and may be...

Imbalance-aware explainable machine learning for concurrent child undernutrition modeling

Abstract Child undernutrition remains a significant public-health issue in Ethiopia, shaped by socioeconomic, environmental, and health-related factors. This study develops a machine-learning (ML) classification model that accounts for concurrent nutritional outcomes in male and...

T218 and K376 Control Phenamacril Sensitivity in Fusarium solani Myosin I and Enable Structure-BasedAntifungal Discovery

Abstract Phenamacril (PHA) is a Fusarium-specific fungicide targeting myosin I, but its sensitivity differs among Fusarium species. The molecular basis of this differential sensitivity remains unclear. Here, we investigated how site-specific variations in Fusarium solani myosin I...

Resilience of health systems in Africa to infectious disease shocks: A qualitative evidence synthesis

Strong and resilient health systems are those equipped to withstand shocks and continue providing quality services as response measures are implemented. We conducted a qualitative evidence synthesis of stakeholders’ understanding of health system resilience in Africa, focusing on...

Mobilizing information in cancer news: How Bengali and English newspapers deliver actionable health messages in Bangladesh

Analyzing cancer news in Bangladesh (2019–2024), this study assesses mobilizing information (MI) in Bangladesh Pratidin (Bengali) and Daily Sun (English). A content analysis of 257 web stories coded MI presence/types, risk factors, sources and prevention focus. MI appeared in 80....

Extracellular membrane vesicles—previously unrecognized components of Staphylococcus aureus biofilms

ABSTRACT Staphylococcus aureus is a leading cause of biofilm-associated infections, in which communities of bacterial cells are encased in an extracellular matrix composed of polysaccharides, proteins, and extracellular DNA (eDNA) that protect bacteria from host immune defense an...

E8-Φ Spatial-Time Harmonization for Emergent Gravity — E8 Intelligence Research

Extrapolating the φ-coup coupling from E8 Vortex Braiding, this principle redefines gravity as a spatial-time resonance arising from the 240 E8 root vectors modulated at 132Hz. The spinor vortices generate φ-synchronized curvature fields that propagate as entangled geometric harm...