Research works

A 256-year daily rainfall record reveals multiscale rainy-season variability and emerging hydroclimatic hazard over northern East Asia

Monsoon rainy seasons shape water supply and flood hazard across northern East Asia, but their long-term variability remains poorly understood because few daily rainfall records extend beyond the instrumental era. Here, we reconstruct rainy-season onset, retreat, and duration fro...

Concurrent synchronization and covariation in upper extremity joint angles during a reciprocal aiming task

Abstract The ecological-dynamical approach holds that movement is self-organized, implying a circular causality between the kinematics of the end-effector and the coordination of degrees of freedom (DOF) into synergies. Yet, how this circular causality manifests itself in redunda...

Physics-enhanced deep learning for dual-branch single-pixel vision via highly scattering media

Single-pixel imaging (SPI) offers sensitivity for optical sensing, but dynamic scattering media severely degrade the captured 1D bucket signals, causing traditional image reconstruction algorithms to fail and hindering target recognition. To overcome the resulting sim-to-real gap...

Overcoming Intra-Articular Delivery Barriers in Cartilage Regeneration: Emerging Controlled-Release Strategies

Articular cartilage has a limited capacity for self-repair due to its avascular nature, dense extracellular matrix, and low cellularity. Current treatments for cartilage injury and osteoarthritis (OA) often provide temporary symptom relief but do not restore native tissue structu...

Probing the Synthetic Landscape of Thorium 2-Aminoterephthalic Acid MOFs: Implications for MOF Characteristics and Iodine Adsorption

Abstract A systematic multiparametric investigation was performed to elucidate the synthesis−structure−property relationship of a UiO-66-type thorium-based 2-aminoterephthalate metal−organic framework (Th-ABDC) for iodine capture. The effects of synthesis temperature (100, 125, 1...

A digital system for assessing psychoemotional stress, mental and cognitive abilities in personnel engaged in high-stress professional activities (medical staff)

Objective. To create a digital model of professional burnout syndrome (PBS) and dynamics of its main manifestations in healthcare workers undergoing combined physiotherapy. Material and methods. The study enrolled 50 healthcare workers (25 ones with PBS and 25 somatically healthy...

ZC3H14 phosphorylation is required for nuclear speckle assembly during zygotic splicing activation in mice

Abstract Following zygotic genome activation (ZGA) in embryos, nuclear speckles, which are subnuclear domains where pre-mRNA undergoes splicing, are reassembled in a process called zygotic splicing activation (ZSA). ZSA is vital for early development, but its regulation is poorly...

Glass Transition of Chiral Hybrid Metal Halides for Self‐Supported 3D Printing

ABSTRACT Hybrid metal halides (HMHs) have emerged as promising functional materials owing to their versatile structural tunability and outstanding optoelectronic properties. In particular, chiral HMHs could be endowed with fascinating chiroptoelectronic properties such as circula...

Long-term immunological impairment after early thymectomy in congenital heart disease

Abstract Early thymectomy during congenital heart disease repair may impair thymic output, but long-term effects across age groups remain incompletely defined. We evaluated T-cell receptor excision circles (TRECs) and a comprehensive panel of lymphocyte subsets in 20 adults (mean...

UAV-based super-resolution instance segmentation enables ecological monitoring of sea cucumbers in shallow coral reef habitats

Accurate monitoring of sea cucumbers from UAV imagery remains challenging because submerged individuals often exhibit low contrast, camouflage against coral-rubble backgrounds, and weak boundary information under water-surface disturbance. In particular, key visual cues such as b...

Latexin deletion in the bone marrow niche suppresses leukemia via LIFR downregulation and immune activation

Acute myeloid leukemia (AML) is the most common adult leukemia diagnosis. Bone marrow (BM) niche significantly influences the initiation and progression of AML. However, our knowledge about the effect of leukemic niche on leukemia stem cells (LSC) and leukemogenesis is limited. I...

Clinical and ecological significance of bacterial dormancy in human pathogens

SUMMARY Bacteria can enter a transient state of reduced metabolic activity to survive temporary unfavorable conditions. This phenomenon, sometimes referred to as dormancy, growth arrest, or quiescence, enables pathogen survival inside and outside of their host, with major clinica...

Zinc and diabetes-related sarcopenia: molecular insights into muscle atrophy in diabetes

Previous reviews have discussed the pathophysiology of diabetic sarcopenia, but none have made any mention of the role of zinc (Zn). This review highlights the emerging role of Zn and Zn-related proteins as potentially important regulators of skeletal muscle mass and function, ad...

Invasive Pneumococcal Disease in Children: A Retrospective Three-Center Study in Zhejiang Province, China (2010–2024)

Invasive pneumococcal diseases (IPD) are among the leading causes of global child mortality. Pneumococcal conjugate vaccines provide direct protection against IPD caused by serotypes included in the vaccine. To investigate the clinical characteristics, serotypes, and antibiotic r...

The relationship between land consolidation and neighboring housing prices – application of quantile regression

Purpose This study aims to use the hedonic price method to explore the relationship between land consolidation and neighboring housing prices. Design/methodology/approach Beginning in the 1980s, with the goal of expediting the city’s development, the Kaohsiung City Government beg...

Visible-Light-Promoted Formal [4 + 3] Radical Annulation of Vinyldiazos: Access to Fluorinated Cyclohepta[ b ]indoles

Abstract Cyclohepta[b]indoles are important nitrogen-containing heterocycles, yet their efficient synthesis remains challenging. Herein, we report a visible-light-promoted formal [4 + 3] cyclization of 3-difluorobromoacetylindoles with vinyldiazos through a photoredox cascade rad...

Codonopsis tangshen Attenuates Age-Related Pulmonary Fibrosis through Senescence and Gut–Lung Axis Modulation

Background: Cellular senescence is a critical driver of chronic inflammation, tissue remodeling, and progressive fibrosis during the aging process. Codonopsis tangshen Oliv. is a widely used medicinal and edible homologous plant in traditional Chinese medicine; however, its pharm...

Damage identification and model updating using bridge displacement under moving vehicles with uncertain weight

Bridge damage incurred during long-term service leads to discrepancies between the physical structure and its digital twin finite element (FE) model, necessitating regular model updates to ensure reliable health monitoring. Traditional methods typically adopt a two-step framework...

A dual-channel deep learning framework integrating preoperative and intraoperative multi-phase data for predicting post-ablation recurrence in atrial fibrillation

Predicting atrial fibrillation (AF) recurrence after catheter ablation is essential for optimizing postoperative management. This study developed the Ablation-Clinical Fusion Transformer (ACFT), a dual-channel framework integrating structured intraoperative ablation sequences wit...

From inequality to oligarchy: Commentary on The Greatest of All Plagues

David Lay Williams's The Greatest of All Plagues is a pathbreaking contribution to political theory. Spanning seven canonical thinkers, from Plato to Marx, the book maintains remarkable cohesiveness, showing that, despite their ideological differences, these thinkers converged in...